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    FUT10 fucosyltransferase 10 [ Homo sapiens (human) ]

    Gene ID: 84750, updated on 17-Jun-2019

    Summary

    Official Symbol
    FUT10provided by HGNC
    Official Full Name
    fucosyltransferase 10provided by HGNC
    Primary source
    HGNC:HGNC:19234
    See related
    Ensembl:ENSG00000172728 MIM:616931
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FUCTX
    Expression
    Ubiquitous expression in ovary (RPKM 2.0), placenta (RPKM 1.5) and 25 other tissues See more
    Orthologs

    Genomic context

    See FUT10 in Genome Data Viewer
    Location:
    8p12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (33308102..33473146, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (33228057..33330664, complement)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379362 Neighboring gene MT-ND2 pseudogene 32 Neighboring gene RAN pseudogene 9 Neighboring gene RNA, U6 small nuclear 528, pseudogene Neighboring gene RNA binding motif protein 4 pseudogene Neighboring gene small nucleolar RNA, C/D box 13 Neighboring gene MAK16 homolog Neighboring gene TELO2 interacting protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC11141

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    alpha-(1->3)-fucosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    alpha-(1->3)-fucosyltransferase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    L-fucose catabolic process NAS
    Non-traceable Author Statement
    more info
    PubMed 
    cerebral cortex radially oriented cell migration IEA
    Inferred from Electronic Annotation
    more info
     
    fertilization NAS
    Non-traceable Author Statement
    more info
    PubMed 
    fucosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    hemopoiesis NAS
    Non-traceable Author Statement
    more info
    PubMed 
    nervous system development NAS
    Non-traceable Author Statement
    more info
    PubMed 
    neuronal stem cell population maintenance IEA
    Inferred from Electronic Annotation
    more info
     
    protein folding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
     
    protein glycosylation TAS
    Traceable Author Statement
    more info
    PubMed 
    protein targeting NAS
    Non-traceable Author Statement
    more info
    PubMed 
    wound healing NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    Golgi apparatus IDA
    Inferred from Direct Assay
    more info
     
    Golgi apparatus TAS
    Traceable Author Statement
    more info
    PubMed 
    Golgi cisterna membrane IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleoplasm IDA
    Inferred from Direct Assay
    more info
     

    General protein information

    Preferred Names
    alpha-(1,3)-fucosyltransferase 10
    Names
    alpha (1,3) fucosyltransferase
    alpha 1,3-fucosyl transferase
    fuc-TX
    fucT-X
    fucosyltransferase X
    galactoside 3-L-fucosyltransferase 10
    NP_116053.3
    XP_011542978.1
    XP_011542979.1
    XP_011542980.1
    XP_011542981.1
    XP_011542982.1
    XP_011542983.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_032664.3NP_116053.3  alpha-(1,3)-fucosyltransferase 10

      See identical proteins and their annotated locations for NP_116053.3

      Status: VALIDATED

      Source sequence(s)
      AJ582015, BC063462
      Consensus CDS
      CCDS6088.1
      UniProtKB/Swiss-Prot
      Q6P4F1
      Related
      ENSP00000332757.5, ENST00000327671.9
      Conserved Domains (2) summary
      pfam00852
      Location:219354
      Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
      pfam17039
      Location:83177
      Glyco_tran_10_N; Fucosyltransferase, N-terminal

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

      Range
      33308102..33473146 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011544676.3XP_011542978.1  alpha-(1,3)-fucosyltransferase 10 isoform X1

      Conserved Domains (2) summary
      pfam00852
      Location:261396
      Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
      pfam17039
      Location:125219
      Glyco_tran_10_N; Fucosyltransferase, N-terminal
    2. XM_011544678.2XP_011542980.1  alpha-(1,3)-fucosyltransferase 10 isoform X3

      Conserved Domains (2) summary
      pfam00852
      Location:191326
      Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
      pfam17039
      Location:55149
      Glyco_tran_10_N; Fucosyltransferase, N-terminal
    3. XM_011544677.3XP_011542979.1  alpha-(1,3)-fucosyltransferase 10 isoform X2

      Conserved Domains (2) summary
      pfam00852
      Location:219354
      Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
      pfam17039
      Location:83177
      Glyco_tran_10_N; Fucosyltransferase, N-terminal
    4. XM_011544681.3XP_011542983.1  alpha-(1,3)-fucosyltransferase 10 isoform X6

      Conserved Domains (2) summary
      pfam00852
      Location:261396
      Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
      pfam17039
      Location:125219
      Glyco_tran_10_N; Fucosyltransferase, N-terminal
    5. XM_011544679.3XP_011542981.1  alpha-(1,3)-fucosyltransferase 10 isoform X4

      Conserved Domains (2) summary
      pfam00852
      Location:261396
      Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
      pfam17039
      Location:125219
      Glyco_tran_10_N; Fucosyltransferase, N-terminal
    6. XM_011544680.3XP_011542982.1  alpha-(1,3)-fucosyltransferase 10 isoform X5

      Conserved Domains (2) summary
      pfam00852
      Location:261396
      Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
      pfam17039
      Location:125219
      Glyco_tran_10_N; Fucosyltransferase, N-terminal
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