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    ACBD6 acyl-CoA binding domain containing 6 [ Homo sapiens (human) ]

    Gene ID: 84320, updated on 17-Jun-2019

    Summary

    Official Symbol
    ACBD6provided by HGNC
    Official Full Name
    acyl-CoA binding domain containing 6provided by HGNC
    Primary source
    HGNC:HGNC:23339
    See related
    Ensembl:ENSG00000230124 MIM:616352
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Ubiquitous expression in testis (RPKM 4.9), placenta (RPKM 3.6) and 25 other tissues See more
    Orthologs

    Genomic context

    See ACBD6 in Genome Data Viewer
    Location:
    1q25.2-q25.3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (180269663..180502577, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (180257352..180472022, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371636 Neighboring gene quiescin sulfhydryl oxidase 1 Neighboring gene LIM homeobox 4 Neighboring gene LHX4 antisense RNA 1 Neighboring gene uncharacterized LOC105371637 Neighboring gene voltage dependent anion channel 1 pseudogene 4 Neighboring gene microRNA 3121 Neighboring gene ovarian adenocarcinoma amplified long non-coding RNA Neighboring gene xenotropic and polytropic retrovirus receptor 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Fatty Acyl-CoA Biosynthesis, organism-specific biosystem (from REACTOME)
      Fatty Acyl-CoA Biosynthesis, organism-specific biosystemFatty acyl-CoA biosynthesis involves following steps: -Palmitate synthesis catalyzed by Acetyl-CoA carboxylase and Fatty acid synthase-Conversion of palmitic acid to long chain fatty acids and-Conver...
    • Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem (from REACTOME)
      Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystemThe reactions involved in the metabolism of fatty acids and of the triacylglycerols and ketone bodies derived from them form a closely interrelated, coordinately regulated module that plays a central...
    • Metabolism, organism-specific biosystem (from REACTOME)
      Metabolism, organism-specific biosystemMetabolic processes in human cells generate energy through the oxidation of molecules consumed in the diet and mediate the synthesis of diverse essential molecules not taken in the diet as well as th...
    • Metabolism of lipids and lipoproteins, organism-specific biosystem (from REACTOME)
      Metabolism of lipids and lipoproteins, organism-specific biosystemLipids are hydrophobic but otherwise chemically diverse molecules that play a wide variety of roles in human biology. They include ketone bodies, fatty acids, triacylglycerols, phospholipids and sphi...
    • Triglyceride Biosynthesis, organism-specific biosystem (from REACTOME)
      Triglyceride Biosynthesis, organism-specific biosystemThe overall process of triglyceride (triacylglycerol) biosynthesis consists of four biochemical pathways: fatty acyl-CoA biosynthesis, conversion of fatty acyl-CoA to phosphatidic acid, conversion of...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC2404

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    fatty-acyl-CoA binding IEA
    Inferred from Electronic Annotation
    more info
     
    lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acyl-CoA metabolic process TAS
    Traceable Author Statement
    more info
     
    Component Evidence Code Pubs
    cytosol TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    acyl-CoA-binding domain-containing protein 6
    Names
    acyl-Coenzyme A binding domain containing 6

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_032360.4NP_115736.1  acyl-CoA-binding domain-containing protein 6

      See identical proteins and their annotated locations for NP_115736.1

      Status: VALIDATED

      Source sequence(s)
      AA085012, AK314112, BU170874
      Consensus CDS
      CCDS1339.1
      UniProtKB/Swiss-Prot
      Q9BR61
      UniProtKB/TrEMBL
      A0A024R915, B2RAA8
      Related
      ENSP00000356567.3, ENST00000367595.4
      Conserved Domains (3) summary
      cd00204
      Location:165261
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:191222
      ANK; ANK repeat [structural motif]
      pfam00887
      Location:44123
      ACBP; Acyl CoA binding protein

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      180269663..180502577 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_002957801.1 RNA Sequence

    2. XR_001737485.2 RNA Sequence

    3. XR_001737484.2 RNA Sequence

    4. XR_921977.3 RNA Sequence

    5. XR_921978.3 RNA Sequence

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