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    POLR3GL RNA polymerase III subunit G like [ Homo sapiens (human) ]

    Gene ID: 84265, updated on 17-Jun-2019

    Summary

    Official Symbol
    POLR3GLprovided by HGNC
    Official Full Name
    RNA polymerase III subunit G likeprovided by HGNC
    Primary source
    HGNC:HGNC:28466
    See related
    Ensembl:ENSG00000121851 MIM:617457
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    RPC32HOM; flj32422
    Expression
    Ubiquitous expression in fat (RPKM 24.4), spleen (RPKM 14.6) and 25 other tissues See more
    Orthologs

    Genomic context

    See POLR3GL in Genome Data Viewer
    Location:
    1q21.1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (145959037..145978848)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (145456236..145476081, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene gonadotropin releasing hormone receptor 2 (pseudogene) Neighboring gene RNA binding motif protein 8A Neighboring gene LIX1L antisense RNA 1 Neighboring gene limb and CNS expressed 1 like Neighboring gene conserved acetylation island sequence C12 enhancer Neighboring gene ankyrin repeat domain 34A Neighboring gene POLR3GL-TXNIP intergenic CAGE-defined low expression enhancer Neighboring gene thioredoxin interacting protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC3200, FLJ34890

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    DNA-directed 5'-3' RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    positive regulation of type I interferon production TAS
    Traceable Author Statement
    more info
     
    transcription by RNA polymerase III IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    RNA polymerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA polymerase III complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol TAS
    Traceable Author Statement
    more info
     
    colocalizes_with nuclear chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with nuclear chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleoplasm TAS
    Traceable Author Statement
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    DNA-directed RNA polymerase III subunit RPC7-like
    Names
    DNA-directed RNA polymerase III subunit G-like
    RNA polymerase III 32 kDa beta subunit
    RNA polymerase III subunit C7-like
    RPC32-beta
    RPC32-like protein
    alternative RNA polymerase III subunit 32
    polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
    polymerase (RNA) III subunit G like

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001330685.1NP_001317614.1  DNA-directed RNA polymerase III subunit RPC7-like isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      BC004355, BI914801, CN261802
      Consensus CDS
      CCDS81367.1
      UniProtKB/Swiss-Prot
      Q9BT43
      UniProtKB/TrEMBL
      A6NGX6
      Related
      ENSP00000358319.3, ENST00000369313.7
      Conserved Domains (1) summary
      pfam11705
      Location:16192
      RNA_pol_3_Rpc31; DNA-directed RNA polymerase III subunit Rpc31
    2. NM_032305.3NP_115681.1  DNA-directed RNA polymerase III subunit RPC7-like isoform 1

      See identical proteins and their annotated locations for NP_115681.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      BC004355, BI914801
      Consensus CDS
      CCDS72875.1
      UniProtKB/Swiss-Prot
      Q9BT43
      Related
      ENSP00000358320.1, ENST00000369314.2
      Conserved Domains (1) summary
      pfam11705
      Location:16204
      RNA_pol_3_Rpc31; DNA-directed RNA polymerase III subunit Rpc31

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      145959037..145978848
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005277431.4XP_005277488.1  DNA-directed RNA polymerase III subunit RPC7-like isoform X1

      See identical proteins and their annotated locations for XP_005277488.1

      UniProtKB/Swiss-Prot
      Q9BT43
      Conserved Domains (1) summary
      pfam11705
      Location:16204
      RNA_pol_3_Rpc31; DNA-directed RNA polymerase III subunit Rpc31
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