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    FYTTD1 forty-two-three domain containing 1 [ Homo sapiens (human) ]

    Gene ID: 84248, updated on 17-Jun-2019

    Summary

    Official Symbol
    FYTTD1provided by HGNC
    Official Full Name
    forty-two-three domain containing 1provided by HGNC
    Primary source
    HGNC:HGNC:25407
    See related
    Ensembl:ENSG00000122068 MIM:616933
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    UIF
    Expression
    Ubiquitous expression in testis (RPKM 31.0), esophagus (RPKM 23.1) and 25 other tissues See more
    Orthologs

    Genomic context

    See FYTTD1 in Genome Data Viewer
    Location:
    3q29
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (197749553..197787596)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (197476424..197511317)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene rubicon autophagy regulator Neighboring gene Sharpr-MPRA regulatory region 8415 Neighboring gene Sharpr-MPRA regulatory region 6653 Neighboring gene leucine rich repeats and calponin homology domain containing 3 Neighboring gene uncharacterized LOC105374310 Neighboring gene ribosomal protein L17 pseudogene 18 Neighboring gene RNA, U6 small nuclear 858, pseudogene Neighboring gene IQ motif containing G

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • DKFZp761B1514

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    RNA binding HDA PubMed 
    mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mRNA export from nucleus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    nuclear speck IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear speck IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    UAP56-interacting factor
    Names
    forty-two-three domain-containing protein 1
    protein 40-2-3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011537.2NP_001011537.2  UAP56-interacting factor isoform 2

      See identical proteins and their annotated locations for NP_001011537.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
      Source sequence(s)
      AJ344094, AK303462, H97483
      Consensus CDS
      CCDS43196.2
      UniProtKB/Swiss-Prot
      Q96QD9
      Related
      ENSP00000393746.2, ENST00000415708.6
      Conserved Domains (1) summary
      pfam07078
      Location:9292
      FYTT; Forty-two-three protein
    2. NM_032288.7NP_115664.2  UAP56-interacting factor isoform 1

      See identical proteins and their annotated locations for NP_115664.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AC055764, AJ344094, BC035006, H97483
      Consensus CDS
      CCDS3329.1
      UniProtKB/Swiss-Prot
      Q96QD9
      UniProtKB/TrEMBL
      A0A024R9K4
      Related
      ENSP00000241502.3, ENST00000241502.9
      Conserved Domains (1) summary
      pfam07078
      Location:13318
      FYTT; Forty-two-three protein

    RNA

    1. NR_027840.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has an alternate 5' exon, compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to inhibit the translation of the longest ORF.
      Source sequence(s)
      AJ344094, AK302546, H97483

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

      Range
      197749553..197787596
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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