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    ZMYM1 zinc finger MYM-type containing 1 [ Homo sapiens (human) ]

    Gene ID: 79830, updated on 2-Oct-2018

    Summary

    Official Symbol
    ZMYM1provided by HGNC
    Official Full Name
    zinc finger MYM-type containing 1provided by HGNC
    Primary source
    HGNC:HGNC:26253
    See related
    Ensembl:ENSG00000197056 Vega:OTTHUMG00000004374
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MYM
    Expression
    Ubiquitous expression in testis (RPKM 3.0), ovary (RPKM 2.8) and 25 other tissues See more
    Orthologs

    Genomic context

    See ZMYM1 in Genome Data Viewer
    Location:
    1p34.3
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 1 NC_000001.11 (35059786..35116458)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (35525387..35581460)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene zinc finger MYM-type containing 6 Neighboring gene ribosomal protein L12 pseudogene 45 Neighboring gene EF-hand calcium binding domain 14 pseudogene 1 Neighboring gene uncharacterized LOC105378644

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ23151, FLJ43753

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of cell morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    zinc finger MYM-type protein 1
    Names
    zinc finger, MYM domain containing 1
    zinc finger, MYM-type 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001289088.1NP_001276017.1  zinc finger MYM-type protein 1 isoform a

      See identical proteins and their annotated locations for NP_001276017.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1, 4, and 5 encode the same protein (isoform a).
      Source sequence(s)
      AK026804, AK125741, BC037313, BX537537
      Consensus CDS
      CCDS41302.1
      UniProtKB/Swiss-Prot
      Q5SVZ6
      UniProtKB/TrEMBL
      A0A1B0GXA6, Q9H5R2
      Related
      ENSP00000482579.1, ENST00000611874.4
      Conserved Domains (5) summary
      smart00597
      Location:452531
      ZnF_TTF; zinc finger in transposases and transcription factors
      smart00746
      Location:135175
      TRASH; metallochaperone-like domain
      pfam05699
      Location:10291118
      Dimer_Tnp_hAT; hAT family C-terminal dimerization region
      pfam06467
      Location:83121
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam14291
      Location:496728
      DUF4371; Domain of unknown function (DUF4371)
    2. NM_001289089.1NP_001276018.1  zinc finger MYM-type protein 1 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (c) has a shorter N-terminus than isoform a.
      Source sequence(s)
      AK026804, AK299779, BC037313, BX537537
      UniProtKB/Swiss-Prot
      Q5SVZ6
      UniProtKB/TrEMBL
      B4DSJ9, Q9H5R2
      Conserved Domains (4) summary
      smart00597
      Location:433512
      ZnF_TTF; zinc finger in transposases and transcription factors
      pfam05699
      Location:10101099
      Dimer_Tnp_hAT; hAT family C-terminal dimerization region
      pfam06467
      Location:130171
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam14291
      Location:477709
      DUF4371; Domain of unknown function (DUF4371)
    3. NM_001289090.1NP_001276019.1  zinc finger MYM-type protein 1 isoform a

      See identical proteins and their annotated locations for NP_001276019.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1, 4, and 5 encode the same protein (isoform a).
      Source sequence(s)
      AK026804, AK299779, BC037313, BX537537
      Consensus CDS
      CCDS41302.1
      UniProtKB/Swiss-Prot
      Q5SVZ6
      UniProtKB/TrEMBL
      B4DSJ9, Q9H5R2
      Related
      ENSP00000362427.1, OTTHUMP00000004598, ENST00000373330.1, OTTHUMT00000012705
      Conserved Domains (5) summary
      smart00597
      Location:452531
      ZnF_TTF; zinc finger in transposases and transcription factors
      smart00746
      Location:135175
      TRASH; metallochaperone-like domain
      pfam05699
      Location:10291118
      Dimer_Tnp_hAT; hAT family C-terminal dimerization region
      pfam06467
      Location:83121
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam14291
      Location:496728
      DUF4371; Domain of unknown function (DUF4371)
    4. NM_001289091.1NP_001276020.1  zinc finger MYM-type protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus than isoform a.
      Source sequence(s)
      AK026804, AK096206, AK299779, BC037313
      UniProtKB/TrEMBL
      B4DSJ9, Q9H5R2
      Conserved Domains (3) summary
      smart00597
      Location:92171
      ZnF_TTF; zinc finger in transposases and transcription factors
      pfam05699
      Location:700758
      Dimer_Tnp_hAT; hAT family C-terminal dimerisation region
      pfam14291
      Location:133367
      DUF4371; Domain of unknown function (DUF4371)
    5. NM_001319955.1NP_001306884.1  zinc finger MYM-type protein 1 isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (d) is shorter at the N-terminus compared to isoform a.
      Source sequence(s)
      AK026804, AK125741, AK299779, BC037313, BX537537, BX648307
      UniProtKB/Swiss-Prot
      Q5SVZ6
      UniProtKB/TrEMBL
      A0A1B0GXA6, B4DSJ9, Q9H5R2
      Conserved Domains (5) summary
      smart00597
      Location:377456
      ZnF_TTF; zinc finger in transposases and transcription factors
      smart00746
      Location:60100
      TRASH; metallochaperone-like domain
      pfam05699
      Location:9541043
      Dimer_Tnp_hAT; hAT family C-terminal dimerization region
      pfam06467
      Location:846
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam14291
      Location:421653
      DUF4371; Domain of unknown function (DUF4371)
    6. NM_024772.4NP_079048.3  zinc finger MYM-type protein 1 isoform a

      See identical proteins and their annotated locations for NP_079048.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 1. Variants 1, 4, and 5 encode the same protein (isoform a).
      Source sequence(s)
      AK026804, AK299779, BC037313, BX537537
      Consensus CDS
      CCDS41302.1
      UniProtKB/Swiss-Prot
      Q5SVZ6
      UniProtKB/TrEMBL
      B4DSJ9, Q9H5R2
      Related
      ENSP00000352920.4, OTTHUMP00000004599, ENST00000359858.8, OTTHUMT00000012706
      Conserved Domains (5) summary
      smart00597
      Location:452531
      ZnF_TTF; zinc finger in transposases and transcription factors
      smart00746
      Location:135175
      TRASH; metallochaperone-like domain
      pfam05699
      Location:10291118
      Dimer_Tnp_hAT; hAT family C-terminal dimerization region
      pfam06467
      Location:83121
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam14291
      Location:496728
      DUF4371; Domain of unknown function (DUF4371)

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p12 Primary Assembly

      Range
      35059786..35116458
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024449828.1XP_024305596.1  zinc finger MYM-type protein 1 isoform X6

      Conserved Domains (3) summary
      smart00597
      Location:261340
      ZnF_TTF; zinc finger in transposases and transcription factors
      pfam05699
      Location:838927
      Dimer_Tnp_hAT; hAT family C-terminal dimerisation region
      pfam14291
      Location:302536
      DUF4371; Domain of unknown function (DUF4371)
    2. XM_017002359.1XP_016857848.1  zinc finger MYM-type protein 1 isoform X5

    3. XM_024449827.1XP_024305595.1  zinc finger MYM-type protein 1 isoform X6

      Conserved Domains (3) summary
      smart00597
      Location:261340
      ZnF_TTF; zinc finger in transposases and transcription factors
      pfam05699
      Location:838927
      Dimer_Tnp_hAT; hAT family C-terminal dimerisation region
      pfam14291
      Location:302536
      DUF4371; Domain of unknown function (DUF4371)
    4. XM_024449824.1XP_024305592.1  zinc finger MYM-type protein 1 isoform X6

      Conserved Domains (3) summary
      smart00597
      Location:261340
      ZnF_TTF; zinc finger in transposases and transcription factors
      pfam05699
      Location:838927
      Dimer_Tnp_hAT; hAT family C-terminal dimerisation region
      pfam14291
      Location:302536
      DUF4371; Domain of unknown function (DUF4371)
    5. XM_024449825.1XP_024305593.1  zinc finger MYM-type protein 1 isoform X6

      Conserved Domains (3) summary
      smart00597
      Location:261340
      ZnF_TTF; zinc finger in transposases and transcription factors
      pfam05699
      Location:838927
      Dimer_Tnp_hAT; hAT family C-terminal dimerisation region
      pfam14291
      Location:302536
      DUF4371; Domain of unknown function (DUF4371)
    6. XM_024449823.1XP_024305591.1  zinc finger MYM-type protein 1 isoform X3

      Conserved Domains (4) summary
      smart00597
      Location:482561
      ZnF_TTF; zinc finger in transposases and transcription factors
      pfam05699
      Location:10591148
      Dimer_Tnp_hAT; hAT family C-terminal dimerisation region
      pfam06467
      Location:161201
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam14291
      Location:523757
      DUF4371; Domain of unknown function (DUF4371)
    7. XM_011542163.3XP_011540465.2  zinc finger MYM-type protein 1 isoform X2

      Conserved Domains (4) summary
      smart00597
      Location:491570
      ZnF_TTF; zinc finger in transposases and transcription factors
      pfam05699
      Location:10681157
      Dimer_Tnp_hAT; hAT family C-terminal dimerisation region
      pfam06467
      Location:182222
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam14291
      Location:532766
      DUF4371; Domain of unknown function (DUF4371)
    8. XM_024449833.1XP_024305601.1  zinc finger MYM-type protein 1 isoform X7

      Conserved Domains (3) summary
      smart00597
      Location:92171
      ZnF_TTF; zinc finger in transposases and transcription factors
      pfam05699
      Location:700758
      Dimer_Tnp_hAT; hAT family C-terminal dimerisation region
      pfam14291
      Location:133367
      DUF4371; Domain of unknown function (DUF4371)
    9. XM_024449822.1XP_024305590.1  zinc finger MYM-type protein 1 isoform X1

      Conserved Domains (4) summary
      smart00597
      Location:503582
      ZnF_TTF; zinc finger in transposases and transcription factors
      pfam05699
      Location:10801169
      Dimer_Tnp_hAT; hAT family C-terminal dimerisation region
      pfam06467
      Location:182222
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam14291
      Location:544778
      DUF4371; Domain of unknown function (DUF4371)
    10. XM_011542165.3XP_011540467.1  zinc finger MYM-type protein 1 isoform X6

      See identical proteins and their annotated locations for XP_011540467.1

      Conserved Domains (3) summary
      smart00597
      Location:261340
      ZnF_TTF; zinc finger in transposases and transcription factors
      pfam05699
      Location:838927
      Dimer_Tnp_hAT; hAT family C-terminal dimerisation region
      pfam14291
      Location:302536
      DUF4371; Domain of unknown function (DUF4371)
    11. XM_017002360.2XP_016857849.1  zinc finger MYM-type protein 1 isoform X6

      Conserved Domains (3) summary
      smart00597
      Location:261340
      ZnF_TTF; zinc finger in transposases and transcription factors
      pfam05699
      Location:838927
      Dimer_Tnp_hAT; hAT family C-terminal dimerisation region
      pfam14291
      Location:302536
      DUF4371; Domain of unknown function (DUF4371)
    12. XM_011542166.3XP_011540468.2  zinc finger MYM-type protein 1 isoform X8

      Related
      ENSP00000394233.1, ENST00000417119.5
      Conserved Domains (1) summary
      pfam06467
      Location:182222
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
    13. XM_017002358.1XP_016857847.1  zinc finger MYM-type protein 1 isoform X4

      Conserved Domains (5) summary
      smart00597
      Location:377456
      ZnF_TTF; zinc finger in transposases and transcription factors
      smart00746
      Location:60100
      TRASH; metallochaperone-like domain
      pfam05699
      Location:9541043
      Dimer_Tnp_hAT; hAT family C-terminal dimerization region
      pfam06467
      Location:846
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam14291
      Location:421653
      DUF4371; Domain of unknown function (DUF4371)
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