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    IGFLR1 IGF like family receptor 1 [ Homo sapiens (human) ]

    Gene ID: 79713, updated on 17-Jun-2019

    Summary

    Official Symbol
    IGFLR1provided by HGNC
    Official Full Name
    IGF like family receptor 1provided by HGNC
    Primary source
    HGNC:HGNC:23620
    See related
    Ensembl:ENSG00000126246 MIM:614143
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TMEM149
    Expression
    Broad expression in lymph node (RPKM 16.7), spleen (RPKM 14.5) and 24 other tissues See more
    Orthologs

    Genomic context

    See IGFLR1 in Genome Data Viewer
    Location:
    19q13.12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (35738801..35742452, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (36229957..36234075, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene thymidylate synthetase pseudogene 2 Neighboring gene zinc finger and BTB domain containing 32 Neighboring gene lysine methyltransferase 2B Neighboring gene U2 small nuclear RNA auxiliary factor 1 like 4 Neighboring gene presenilin enhancer, gamma-secretase subunit

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ22573

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    IGF-like family receptor 1
    Names
    transmembrane protein 149

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001346003.2NP_001332932.1  IGF-like family receptor 1 isoform b precursor

      Status: VALIDATED

      Source sequence(s)
      AD000671
      Consensus CDS
      CCDS86752.1
      UniProtKB/TrEMBL
      K7EL86
      Related
      ENSP00000465962.1, ENST00000588992.5
    2. NM_001346004.2NP_001332933.1  IGF-like family receptor 1 isoform c precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3), as well as variant 4, encodes isoform c.
      Source sequence(s)
      AD000671
      Consensus CDS
      CCDS86751.1
      UniProtKB/Swiss-Prot
      Q9H665
      Related
      ENSP00000467750.1, ENST00000592889.1
    3. NM_001346005.2NP_001332934.1  IGF-like family receptor 1 isoform c precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4), as well as variant 3, encodes isoform c.
      Source sequence(s)
      AD000671
      Consensus CDS
      CCDS86751.1
      UniProtKB/Swiss-Prot
      Q9H665
    4. NM_001346006.2NP_001332935.1  IGF-like family receptor 1 isoform d precursor

      Status: VALIDATED

      Source sequence(s)
      AD000671
    5. NM_024660.4NP_078936.1  IGF-like family receptor 1 isoform a precursor

      See identical proteins and their annotated locations for NP_078936.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
      Source sequence(s)
      AD000671, AK026226, BU621457
      Consensus CDS
      CCDS12472.1
      UniProtKB/Swiss-Prot
      Q9H665
      Related
      ENSP00000246532.1, ENST00000246532.6

    RNA

    1. NR_144338.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AD000671, AK026226, BC144205, BU621457
    2. NR_144339.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AD000671
    3. NR_144340.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AD000671
    4. NR_144341.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AD000671
    5. NR_144342.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AD000671

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

      Range
      35738801..35742452 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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