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    ZNF576 zinc finger protein 576 [ Homo sapiens (human) ]

    Gene ID: 79177, updated on 17-Jun-2019

    Summary

    Official Symbol
    ZNF576provided by HGNC
    Official Full Name
    zinc finger protein 576provided by HGNC
    Primary source
    HGNC:HGNC:28357
    See related
    Ensembl:ENSG00000124444
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Ubiquitous expression in prostate (RPKM 1.5), fat (RPKM 1.4) and 25 other tissues See more
    Orthologs

    Genomic context

    See ZNF576 in Genome Data Viewer
    Location:
    19q13.31
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (43596392..43601157)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (44100544..44104587)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene X-ray repair cross complementing 1 Neighboring gene phospholipase A2 inhibitor and LY6/PLAUR domain containing Neighboring gene immunity related GTPase Q Neighboring gene zinc finger protein 428 Neighboring gene uncharacterized LOC105372411 Neighboring gene serine/arginine repetitive matrix 5 Neighboring gene cell adhesion molecule 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Potential readthrough

    Included gene: SRRM5

    Homology

    Clone Names

    • MGC2508, FLJ22700, FLJ56397

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity, RNA polymerase II-specific ISA
    Inferred from Sequence Alignment
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145347.2NP_001138819.1  zinc finger protein 576

      See identical proteins and their annotated locations for NP_001138819.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC006276, BC002981, BP358040
      Consensus CDS
      CCDS12625.1
      UniProtKB/Swiss-Prot
      Q9H609
      UniProtKB/TrEMBL
      A0A024R0T0
      Related
      ENSP00000337852.4, ENST00000336564.4
      Conserved Domains (2) summary
      sd00017
      Location:7393
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:112134
      zf-C2H2; Zinc finger, C2H2 type
    2. NM_024327.2NP_077303.1  zinc finger protein 576

      See identical proteins and their annotated locations for NP_077303.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC006276, AK026353
      Consensus CDS
      CCDS12625.1
      UniProtKB/Swiss-Prot
      Q9H609
      UniProtKB/TrEMBL
      A0A024R0T0
      Related
      ENSP00000375827.2, ENST00000391965.6
      Conserved Domains (2) summary
      sd00017
      Location:7393
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:112134
      zf-C2H2; Zinc finger, C2H2 type

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

      Range
      43596392..43601157
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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