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    ZNF705D zinc finger protein 705D [ Homo sapiens (human) ]

    Gene ID: 728957, updated on 15-Jun-2019

    Summary

    Official Symbol
    ZNF705Dprovided by HGNC
    Official Full Name
    zinc finger protein 705Dprovided by HGNC
    Primary source
    HGNC:HGNC:33202
    See related
    Ensembl:ENSG00000215343
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ZNF705C
    Annotation information
    Annotation category: spans an assembly gap
    Expression
    Low expression observed in reference dataset See more
    Orthologs

    Genomic context

    See ZNF705D in Genome Data Viewer
    Location:
    8p23.1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 8 NC_000008.11 (12089338..12115516)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (11946847..11973025)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene defensin beta 130B Neighboring gene RNA, 5S ribosomal pseudogene 253 Neighboring gene defensin beta 108D (pseudogene) Neighboring gene family with sequence similarity 66 member D Neighboring gene ubiquitin specific peptidase 17-like family member 2 pseudogene Neighboring gene ubiquitin specific peptidase 17 like family member 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Gene Expression, organism-specific biosystem (from REACTOME)
      Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
    • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
      Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...

    General gene information

    Markers

    Homology

    Clone Names

    • MGC131746

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity, RNA polymerase II-specific ISA
    Inferred from Sequence Alignment
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    zinc finger protein 705D
    Names
    putative zinc finger protein 705C
    zinc finger protein 705C

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039615.3NP_001034704.2  zinc finger protein 705D

      See identical proteins and their annotated locations for NP_001034704.2

      Status: VALIDATED

      Source sequence(s)
      AC130366
      Consensus CDS
      CCDS43712.1
      UniProtKB/Swiss-Prot
      P0CH99
      Related
      ENSP00000382957.3, ENST00000400085.7
      Conserved Domains (5) summary
      smart00349
      Location:766
      KRAB; krueppel associated box
      COG5048
      Location:116300
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:174194
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:746
      KRAB; KRAB box
      pfam13465
      Location:214239
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

      Range
      12089338..12115516
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011543832.2XP_011542134.1  zinc finger protein 705D isoform X1

      See identical proteins and their annotated locations for XP_011542134.1

      UniProtKB/Swiss-Prot
      P0CH99
      Related
      ENSP00000445477.2, ENST00000400078.3
      Conserved Domains (5) summary
      smart00349
      Location:766
      KRAB; krueppel associated box
      COG5048
      Location:116300
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:174194
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:746
      KRAB; KRAB box
      pfam13465
      Location:214239
      zf-H2C2_2; Zinc-finger double domain
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