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    MEIKIN meiotic kinetochore factor [ Homo sapiens (human) ]

    Gene ID: 728637, updated on 17-Jun-2019

    Summary

    Official Symbol
    MEIKINprovided by HGNC
    Official Full Name
    meiotic kinetochore factorprovided by HGNC
    Primary source
    HGNC:HGNC:51253
    See related
    Ensembl:ENSG00000239642 MIM:616232
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Restricted expression toward testis (RPKM 3.3) See more
    Orthologs

    Genomic context

    See MEIKIN in Genome Data Viewer
    Location:
    5q31.1
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (131806990..131945663, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (131142683..131281391, complement)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene Rap guanine nucleotide exchange factor 6 Neighboring gene folliculin interacting protein 1 Neighboring gene ACTB pseudogene 4 Neighboring gene uncharacterized LOC101927693 Neighboring gene acyl-CoA synthetase long chain family member 6 Neighboring gene uncharacterized LOC105379174 Neighboring gene interleukin 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    General gene information

    Markers

    Potential readthrough

    Included gene: ACSL6

    Homology

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    female meiosis chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    female meiosis chromosome segregation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    homologous chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    homologous chromosome segregation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    male meiosis chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    male meiosis chromosome segregation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    meiotic sister chromatid cohesion involved in meiosis I IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    meiotic sister chromatid cohesion involved in meiosis I ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    meiotic sister chromatid cohesion, centromeric IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    meiotic sister chromatid cohesion, centromeric ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    condensed chromosome kinetochore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    condensed chromosome kinetochore ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    condensed nuclear chromosome, centromeric region IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    condensed nuclear chromosome, centromeric region ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    meiosis-specific kinetochore protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001303622.2NP_001290551.1  meiosis-specific kinetochore protein

      See identical proteins and their annotated locations for NP_001290551.1

      Status: VALIDATED

      Source sequence(s)
      AB987829, BG181951, DB455285
      Consensus CDS
      CCDS75292.2
      UniProtKB/Swiss-Prot
      A0A087WXM9
      Related
      ENSP00000488568.1, ENST00000442687.6

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

      Range
      131806990..131945663 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001278059.1: Suppressed sequence

      Description
      NM_001278059.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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