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    KRTAP2-2 keratin associated protein 2-2 [ Homo sapiens (human) ]

    Gene ID: 728279, updated on 13-Feb-2019

    Summary

    Official Symbol
    KRTAP2-2provided by HGNC
    Official Full Name
    keratin associated protein 2-2provided by HGNC
    Primary source
    HGNC:HGNC:18905
    See related
    Ensembl:ENSG00000214518
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    KAP2.1; KAP2.2; KRTAP2-1; KRTAP2.1A; KRTAP2.1B

    Genomic context

    See KRTAP2-2 in Genome Data Viewer
    Location:
    17q21.2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 17 NC_000017.11 (41054498..41055211, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (39210750..39211463, complement)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene keratin associated protein 1-1 Neighboring gene keratin associated protein 2-1 Neighboring gene keratin associated protein 2-3 Neighboring gene keratin associated protein 2-4

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Developmental Biology, organism-specific biosystem (from REACTOME)
      Developmental Biology, organism-specific biosystemAs a first step towards capturing the array of processes by which a fertilized egg gives rise to the diverse tissues of the body, examples of three kinds of processes have been annotated. These are a...
    • Keratinization, organism-specific biosystem (from REACTOME)
      Keratinization, organism-specific biosystemKeratins are the major structural protein of vertebrate epidermis, constituting up to 85% of a fully differentiated keratinocyte (Fuchs 1995). Keratins belong to a superfamily of intermediate filamen...

    General protein information

    Preferred Names
    putative keratin-associated protein ENSP00000381495
    Names
    High sulfur keratin-associated protein 2.1
    Keratin-associated protein 2-1
    Keratin-associated protein 2.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033032.2NP_149021.2  putative keratin-associated protein ENSP00000381495

      See identical proteins and their annotated locations for NP_149021.2

      Status: VALIDATED

      Source sequence(s)
      AC100808
      Consensus CDS
      CCDS54122.1
      UniProtKB/Swiss-Prot
      Q9BYT5
      Related
      ENSP00000381494.1, ENST00000398477.1
      Conserved Domains (2) summary
      pfam01500
      Location:2123
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam13885
      Location:58102
      Keratin_B2_2; Keratin, high sulfur B2 protein

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p12 Primary Assembly

      Range
      41054498..41055211 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p12 ALT_REF_LOCI_1

    Genomic

    1. NW_003871091.1 Reference GRCh38.p12 ALT_REF_LOCI_1

      Range
      203891..204709 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017030240.1XP_016885729.1  putative keratin-associated protein ENSP00000381495 isoform X1

      UniProtKB/Swiss-Prot
      Q9BYU5
      Conserved Domains (2) summary
      pfam01500
      Location:2128
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam13885
      Location:73117
      Keratin_B2_2; Keratin, high sulfur B2 protein
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