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    Arid5b AT rich interactive domain 5B (MRF1-like) [ Mus musculus (house mouse) ]

    Gene ID: 71371, updated on 31-Jan-2019

    Summary

    Official Symbol
    Arid5bprovided by MGI
    Official Full Name
    AT rich interactive domain 5B (MRF1-like)provided by MGI
    Primary source
    MGI:MGI:2175912
    See related
    Ensembl:ENSMUSG00000019947
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mrf2; Desrt; AI467247; Mrf2beta; Mrf2alpha; 4930580B11; 5430435G07Rik
    Expression
    Ubiquitous expression in lung adult (RPKM 5.8), bladder adult (RPKM 5.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Arid5b in Genome Data Viewer
    Location:
    10; 10 B5.2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (68092523..68278726, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (67558341..67741474, complement)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930521O17 gene Neighboring gene rhotekin 2 Neighboring gene RIKEN cDNA 4930545H06 gene Neighboring gene predicted gene, 32748

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    RNA polymerase II regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    transcription regulatory region DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription regulatory region DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    adipose tissue development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    adrenal gland development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to leukemia inhibitory factor IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    face morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fat cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fat pad development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    female gonad development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fibroblast migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    kidney development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    male gonad development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    muscle organ morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    nitrogen compound metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    platelet-derived growth factor receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of DNA-binding transcription factor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of DNA-binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    post-embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    roof of mouth development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    skeletal system morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    AT-rich interactive domain-containing protein 5B
    Names
    ARID class DNA binding protein
    ARID domain-containing protein 5B
    AT rich interactive domain 5B (Mrf1 like)
    MRF-2
    developmentally and sexually retarded with transient immune abnormalities protein
    modulator recognition factor 2
    modulator recognition factor protein 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023598.2NP_076087.2  AT-rich interactive domain-containing protein 5B

      See identical proteins and their annotated locations for NP_076087.2

      Status: VALIDATED

      Source sequence(s)
      AK029818, AK034633, BY717211, BY720203, CD543091, CN665657
      Consensus CDS
      CCDS35929.1
      UniProtKB/Swiss-Prot
      Q8BM75
      Related
      ENSMUSP00000151227.1, ENSMUST00000219238.1
      Conserved Domains (2) summary
      smart00501
      Location:320412
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      cl02608
      Location:34108
      BAH; BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      68092523..68278726 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006514130.3XP_006514193.1  AT-rich interactive domain-containing protein 5B isoform X2

      Conserved Domains (1) summary
      smart00501
      Location:346430
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
    2. XM_006514129.3XP_006514192.1  AT-rich interactive domain-containing protein 5B isoform X1

      Conserved Domains (1) summary
      smart00501
      Location:346438
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
    3. XM_006514133.2XP_006514196.1  AT-rich interactive domain-containing protein 5B isoform X4

      See identical proteins and their annotated locations for XP_006514196.1

      Conserved Domains (1) summary
      smart00501
      Location:131223
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
    4. XM_006514132.2XP_006514195.1  AT-rich interactive domain-containing protein 5B isoform X4

      See identical proteins and their annotated locations for XP_006514195.1

      Conserved Domains (1) summary
      smart00501
      Location:131223
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
    5. XM_006514131.3XP_006514194.1  AT-rich interactive domain-containing protein 5B isoform X3

      Related
      ENSMUSP00000151665.1, ENSMUST00000218532.1
      Conserved Domains (1) summary
      smart00501
      Location:134226
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
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