Format

Send to:

Choose Destination
    • Showing Current items.

    Mitd1 MIT, microtubule interacting and transport, domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 69028, updated on 31-Jan-2019

    Summary

    Official Symbol
    Mitd1provided by MGI
    Official Full Name
    MIT, microtubule interacting and transport, domain containing 1provided by MGI
    Primary source
    MGI:MGI:1916278
    See related
    Ensembl:ENSMUSG00000026088
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1500032H18Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 6.1), liver E14 (RPKM 4.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Mitd1 in Genome Data Viewer
    Location:
    1; 1 B
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (37878888..37890442, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (37935735..37947256, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene testis specific 10 Neighboring gene lipoyltransferase 1 Neighboring gene mitochondrial ribosomal protein L30 Neighboring gene lysozyme G-like 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    phosphatidylinositol binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    midbody abscission ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    endosome IEA
    Inferred from Electronic Annotation
    more info
     
    extrinsic component of membrane ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    midbody ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with midbody ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    MIT domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356262.1NP_001343191.1  MIT domain-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      AC119189
      Conserved Domains (2) summary
      cd02683
      Location:1086
      MIT_1; MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in proteins with unknown function, co-occuring with an as yet undescribed domain. The molecular function of the MIT domain is unclear.
      pfam16565
      Location:100242
      MIT_C; Phospholipase D-like domain at C-terminus of MIT
    2. NM_026913.3NP_081189.1  MIT domain-containing protein 1

      See identical proteins and their annotated locations for NP_081189.1

      Status: VALIDATED

      Source sequence(s)
      AC119189
      Consensus CDS
      CCDS35542.1
      UniProtKB/Swiss-Prot
      Q8VDV8
      Related
      ENSMUSP00000027257.8, ENSMUST00000027257.9
      Conserved Domains (2) summary
      cd02683
      Location:1086
      MIT_1; MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in proteins with unknown function, co-occuring with an as yet undescribed domain. The molecular function of the MIT domain is unclear.
      pfam16565
      Location:100242
      MIT_C; Phospholipase D-like domain at C-terminus of MIT

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      37878888..37890442 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017322349.1XP_017177838.1  MIT domain-containing protein 1 isoform X2

    2. XM_011238588.2XP_011236890.1  MIT domain-containing protein 1 isoform X1

      Conserved Domains (2) summary
      cd02683
      Location:1086
      MIT_1; MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in proteins with unknown function, co-occuring with an as yet undescribed domain. The molecular function of the MIT domain is unclear.
      cl02780
      Location:100199
      MIT_C; MIT_C; domain found C-terminal to MIT (contained within Microtubule Interacting and Trafficking molecules) domains, as well as in some bacterial proteins. The function of this domain is unknown.

    RNA

    1. XR_001785585.1 RNA Sequence

    Support Center