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    Arhgef10l Rho guanine nucleotide exchange factor 10 like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 684811, updated on 18-Apr-2019

    Summary

    Official Symbol
    Arhgef10lprovided by RGD
    Official Full Name
    Rho guanine nucleotide exchange factor 10 likeprovided by RGD
    Primary source
    RGD:1585585
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Kidney (RPKM 118.1), Muscle (RPKM 104.7) and 9 other tissues See more

    Genomic context

    See Arhgef10l in Genome Data Viewer
    Location:
    5q36
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (159018373..159089383, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 5 NC_005104.3 (162726280..162827970, complement)

    Chromosome 5 - NC_005104.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108351052 Neighboring gene kelch domain containing 7A Neighboring gene uncharacterized LOC102547437 Neighboring gene immunoglobin superfamily, member 21 Neighboring gene rho guanine nucleotide exchange factor 10-like protein Neighboring gene regulator of chromosome condensation 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    GTPase activator activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Rho guanyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    guanyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    SREBP signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    SREBP signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of stress fiber assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of stress fiber assembly ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    rho guanine nucleotide exchange factor 10-like protein
    Names
    Rho guanine nucleotide exchange factor (GEF) 10-like

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005104.4 Reference Rnor_6.0 Primary Assembly

      Range
      159018373..159089383 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017593863.1XP_017449352.1  rho guanine nucleotide exchange factor 10-like protein isoform X1

    Alternate Rn_Celera

    Genomic

    1. AC_000073.1 Alternate Rn_Celera

      Range
      151154621..151224945 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017603137.1XP_017458626.1  rho guanine nucleotide exchange factor 10-like protein isoform X4

    2. XM_017603136.1XP_017458625.1  rho guanine nucleotide exchange factor 10-like protein isoform X3

    3. XM_017603135.1XP_017458624.1  rho guanine nucleotide exchange factor 10-like protein isoform X2

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