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    MT1HL1 metallothionein 1H like 1 [ Homo sapiens (human) ]

    Gene ID: 645745, updated on 17-Jun-2019

    Summary

    Official Symbol
    MT1HL1provided by HGNC
    Official Full Name
    metallothionein 1H like 1provided by HGNC
    Primary source
    HGNC:HGNC:31864
    See related
    Ensembl:ENSG00000244020
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MT1P2
    Summary
    This gene is a retrotransposed gene, compared to MT1H (GeneID:4496). This retrogene is transcribed. It retains a full-length CDS, and is assumed to be translated. Compared to the MT1H product, this protein product differs at three internal amino acids, two of which are at metal-binding sites. [provided by RefSeq, Mar 2013]
    Orthologs

    Genomic context

    See MT1HL1 in Genome Data Viewer
    Location:
    1q43
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (237004103..237004441, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (237167403..237167718, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107985368 Neighboring gene VISTA enhancer hs2137 Neighboring gene VISTA enhancer hs2138 Neighboring gene ribosomal protein L35 pseudogene 1 Neighboring gene ryanodine receptor 2 Neighboring gene RN7SK pseudogene 195

    Genomic regions, transcripts, and products

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Mineral absorption, organism-specific biosystem (from KEGG)
      Mineral absorption, organism-specific biosystemMinerals are one of the five fundamental groups of nutrients needed to sustain life. Of the minerals, calcium plays innumerable roles in our bodies, serving as a main component of bone as well as an ...
    • Mineral absorption, conserved biosystem (from KEGG)
      Mineral absorption, conserved biosystemMinerals are one of the five fundamental groups of nutrients needed to sustain life. Of the minerals, calcium plays innumerable roles in our bodies, serving as a main component of bone as well as an ...

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    metal ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    cellular response to cadmium ion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular response to copper ion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular response to zinc ion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular zinc ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    detoxification of copper ion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    metallothionein 1H-like protein 1
    Names
    MT-1H-like protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001276687.2NP_001263616.1  metallothionein 1H-like protein 1

      See identical proteins and their annotated locations for NP_001263616.1

      Status: VALIDATED

      Source sequence(s)
      AF333388, AL359259
      Consensus CDS
      CCDS31068.1
      UniProtKB/Swiss-Prot
      P0DM35
      Related
      ENSP00000476141.1, ENST00000464121.2
      Conserved Domains (1) summary
      pfam00131
      Location:561
      Metallothio; Metallothionein

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      237004103..237004441 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_007037.2: Suppressed sequence

      Description
      NG_007037.2: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein and is not a pseudogene.
    2. NM_001039954.2: Suppressed sequence

      Description
      NM_001039954.2: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
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