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    DHFRP1 dihydrofolate reductase pseudogene 1 [ Homo sapiens (human) ]

    Gene ID: 573971, updated on 15-Jun-2019

    Summary

    Official Symbol
    DHFRP1provided by HGNC
    Official Full Name
    dihydrofolate reductase pseudogene 1provided by HGNC
    Primary source
    HGNC:HGNC:2862
    Gene type
    pseudo
    RefSeq status
    INFERRED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo

    Genomic context

    See DHFRP1 in Genome Data Viewer
    Location:
    18q11.2
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 18 NC_000018.10 (26167862..26171357, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (23747826..23751321, complement)

    Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene SS18 subunit of BAF chromatin remodeling complex Neighboring gene ribosomal protein S24 pseudogene 18 Neighboring gene proteasome subunit alpha 8 Neighboring gene nucleophosmin 1 pseudogene 2 Neighboring gene TATA-box binding protein associated factor 4b Neighboring gene SINHCAF pseudogene 1

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Markers

    Other Names

    • hDHFR-psi 3

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    NADP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    NADPH binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dihydrofolate reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    dihydrofolate reductase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dihydrofolate reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    dihydrofolate reductase activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    drug binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    folic acid binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    methotrexate binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    sequence-specific mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    translation repressor activity, mRNA regulatory element binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    axon regeneration ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    dihydrofolate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    dihydrofolate metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    folic acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    folic acid metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    folic acid metabolic process TAS
    Traceable Author Statement
    more info
     
    negative regulation of translation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    one-carbon metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    oxidation-reduction process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of nitric-oxide synthase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of removal of superoxide radicals ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of transcription involved in G1/S transition of mitotic cell cycle TAS
    Traceable Author Statement
    more info
     
    response to methotrexate ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    tetrahydrobiopterin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    tetrahydrobiopterin biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    tetrahydrofolate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    tetrahydrofolate biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    tetrahydrofolate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    tetrahydrofolate metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol TAS
    Traceable Author Statement
    more info
     
    mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_005427.7 

      Range
      101..3596
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000018.10 Reference GRCh38.p13 Primary Assembly

      Range
      26167862..26171357 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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