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    ATP13A1 ATPase 13A1 [ Homo sapiens (human) ]

    Gene ID: 57130, updated on 12-Oct-2019

    Summary

    Official Symbol
    ATP13A1provided by HGNC
    Official Full Name
    ATPase 13A1provided by HGNC
    Primary source
    HGNC:HGNC:24215
    See related
    Ensembl:ENSG00000105726
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ATP13A; CGI-152
    Expression
    Ubiquitous expression in spleen (RPKM 18.6), testis (RPKM 14.9) and 25 other tissues See more
    Orthologs

    Genomic context

    See ATP13A1 in Genome Data Viewer
    Location:
    19p13.11
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    109.20190905 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (19645198..19663676, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (19756007..19774512, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene lysophosphatidic acid receptor 2 Neighboring gene GEM interacting protein Neighboring gene conserved acetylation island sequence C14 enhancer Neighboring gene zinc finger protein 101 Neighboring gene zinc finger protein 14

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ31858, FLJ41786, FLJ43873, FLJ90317, KIAA1825, DKFZp761L1623

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    manganese-transporting ATPase activity TAS
    Traceable Author Statement
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    cellular calcium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ion transmembrane transport TAS
    Traceable Author Statement
    more info
     
    manganese ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum membrane TAS
    Traceable Author Statement
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane HDA PubMed 

    General protein information

    Preferred Names
    manganese-transporting ATPase 13A1
    Names
    ATPase type 13A1
    cation transporting ATPase
    probable cation-transporting ATPase 13A1
    NP_065143.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020410.3NP_065143.2  manganese-transporting ATPase 13A1

      See identical proteins and their annotated locations for NP_065143.2

      Status: VALIDATED

      Source sequence(s)
      AB058728, BC009302, DA103408
      Consensus CDS
      CCDS32970.2
      UniProtKB/Swiss-Prot
      Q9HD20
      UniProtKB/TrEMBL
      A0A024R7N2
      Related
      ENSP00000349877.6, ENST00000357324.11
      Conserved Domains (5) summary
      COG4087
      Location:831884
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01657
      Location:851173
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:298510
      E1-E2_ATPase; E1-E2 ATPase
      pfam12710
      Location:643873
      HAD; haloacid dehalogenase-like hydrolase
      pfam13246
      Location:584667
      Cation_ATPase; Cation transport ATPase (P-type)

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

      Range
      19645198..19663676 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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