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    TCP11L1 t-complex 11 like 1 [ Homo sapiens (human) ]

    Gene ID: 55346, updated on 17-Jun-2024

    Summary

    Official Symbol
    TCP11L1provided by HGNC
    Official Full Name
    t-complex 11 like 1provided by HGNC
    Primary source
    HGNC:HGNC:25655
    See related
    Ensembl:ENSG00000176148 AllianceGenome:HGNC:25655
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    dJ85M6.3
    Summary
    Predicted to be involved in signal transduction. Located in microtubule. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in brain (RPKM 7.3), small intestine (RPKM 3.3) and 25 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See TCP11L1 in Genome Data Viewer
    Location:
    11p13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (33039572..33073563)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (33175146..33209116)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (33061118..33095109)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene glutamine and serine rich 1 Neighboring gene uncharacterized LOC105376615 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:33022947-33023448 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4569 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4570 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3229 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3230 Neighboring gene DEP domain containing 7 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:33060521-33061068 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3231 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4572 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:33071407-33071907 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:33082368-33083567 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:33089797-33090298 Neighboring gene long intergenic non-protein coding RNA 294 Neighboring gene phosphatidylinositol glycan anchor biosynthesis class C pseudogene 1 Neighboring gene cleavage stimulation factor subunit 3 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:33181388-33182255 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4574

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ11336, FLJ11386

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in microtubule IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    T-complex protein 11-like protein 1
    Names
    t-complex 11, testis-specific-like 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145541.1NP_001139013.1  T-complex protein 11-like protein 1

      See identical proteins and their annotated locations for NP_001139013.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC131263, AK002198, BP281502, DA340843
      Consensus CDS
      CCDS7882.1
      UniProtKB/Swiss-Prot
      D3DR01, Q8IVX4, Q9NUJ3
      UniProtKB/TrEMBL
      B3KQZ4
      Related
      ENSP00000395070.1, ENST00000432887.5
      Conserved Domains (1) summary
      pfam05794
      Location:78502
      Tcp11; T-complex protein 11
    2. NM_018393.4NP_060863.3  T-complex protein 11-like protein 1

      See identical proteins and their annotated locations for NP_060863.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC131263, AK090646, BP281502, DA088926
      Consensus CDS
      CCDS7882.1
      UniProtKB/Swiss-Prot
      D3DR01, Q8IVX4, Q9NUJ3
      UniProtKB/TrEMBL
      B3KQZ4
      Related
      ENSP00000335595.4, ENST00000334274.9
      Conserved Domains (1) summary
      pfam05794
      Location:78502
      Tcp11; T-complex protein 11

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      33039572..33073563
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011520207.3XP_011518509.1  T-complex protein 11-like protein 1 isoform X2

      See identical proteins and their annotated locations for XP_011518509.1

      UniProtKB/Swiss-Prot
      D3DR01, Q8IVX4, Q9NUJ3
      UniProtKB/TrEMBL
      B3KQZ4
      Related
      ENSP00000433067.1, ENST00000531632.6
      Conserved Domains (1) summary
      pfam05794
      Location:78502
      Tcp11; T-complex protein 11
    2. XM_017017989.3XP_016873478.1  T-complex protein 11-like protein 1 isoform X1

      UniProtKB/TrEMBL
      B3KQZ4
      Conserved Domains (1) summary
      pfam05794
      Location:78505
      Tcp11; T-complex protein 11
    3. XM_047427237.1XP_047283193.1  T-complex protein 11-like protein 1 isoform X4

    4. XM_011520205.3XP_011518507.1  T-complex protein 11-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011518507.1

      UniProtKB/TrEMBL
      B3KQZ4
      Conserved Domains (1) summary
      pfam05794
      Location:78505
      Tcp11; T-complex protein 11
    5. XM_017017990.2XP_016873479.1  T-complex protein 11-like protein 1 isoform X2

      UniProtKB/Swiss-Prot
      D3DR01, Q8IVX4, Q9NUJ3
      UniProtKB/TrEMBL
      B3KQZ4
      Conserved Domains (1) summary
      pfam05794
      Location:78502
      Tcp11; T-complex protein 11
    6. XM_011520206.3XP_011518508.1  T-complex protein 11-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011518508.1

      UniProtKB/TrEMBL
      B3KQZ4
      Conserved Domains (1) summary
      pfam05794
      Location:78505
      Tcp11; T-complex protein 11
    7. XM_011520204.3XP_011518506.1  T-complex protein 11-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011518506.1

      UniProtKB/TrEMBL
      B3KQZ4
      Conserved Domains (1) summary
      pfam05794
      Location:78505
      Tcp11; T-complex protein 11
    8. XM_047427236.1XP_047283192.1  T-complex protein 11-like protein 1 isoform X3

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      33175146..33209116
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054369299.1XP_054225274.1  T-complex protein 11-like protein 1 isoform X1

      UniProtKB/TrEMBL
      B3KQZ4
    2. XM_054369307.1XP_054225282.1  T-complex protein 11-like protein 1 isoform X4

    3. XM_054369304.1XP_054225279.1  T-complex protein 11-like protein 1 isoform X2

      UniProtKB/TrEMBL
      B3KQZ4
    4. XM_054369303.1XP_054225278.1  T-complex protein 11-like protein 1 isoform X2

      UniProtKB/TrEMBL
      B3KQZ4
    5. XM_054369300.1XP_054225275.1  T-complex protein 11-like protein 1 isoform X1

      UniProtKB/TrEMBL
      B3KQZ4
    6. XM_054369301.1XP_054225276.1  T-complex protein 11-like protein 1 isoform X1

      UniProtKB/TrEMBL
      B3KQZ4
    7. XM_054369302.1XP_054225277.1  T-complex protein 11-like protein 1 isoform X1

      UniProtKB/TrEMBL
      B3KQZ4
    8. XM_054369305.1XP_054225280.1  T-complex protein 11-like protein 1 isoform X5

      UniProtKB/TrEMBL
      B3KQZ4
    9. XM_054369306.1XP_054225281.1  T-complex protein 11-like protein 1 isoform X3