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    SETD5 SET domain containing 5 [ Homo sapiens (human) ]

    Gene ID: 55209, updated on 17-Jun-2024

    Summary

    Official Symbol
    SETD5provided by HGNC
    Official Full Name
    SET domain containing 5provided by HGNC
    Primary source
    HGNC:HGNC:25566
    See related
    Ensembl:ENSG00000168137 MIM:615743; AllianceGenome:HGNC:25566
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MRD23; SETD5A
    Summary
    This function of this gene has yet to be determined but based on sequence similarity to other SET domain proteins it may function as a histone methyltransferase. Mutations in this gene have been associated with an autosomal dominant form of intellectual disability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017]
    Expression
    Ubiquitous expression in brain (RPKM 9.1), thyroid (RPKM 9.1) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See SETD5 in Genome Data Viewer
    Location:
    3p25.3
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (9397615..9478154)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (9389553..9470070)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (9439299..9519838)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene SLIT-ROBO Rho GTPase activating protein 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19399 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19400 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19401 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19402 Neighboring gene phosphoglycerate mutase 1 pseudogene 4 Neighboring gene THUMPD3 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14033 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19403 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr3:9444537-9445037 Neighboring gene Sharpr-MPRA regulatory region 11896 Neighboring gene THUMP domain containing 3 Neighboring gene MPRA-validated peak4533 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:9543010-9543735 Neighboring gene Sharpr-MPRA regulatory region 15302 Neighboring gene LHFPL tetraspan subfamily member 4 Neighboring gene uncharacterized LOC105376949

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    Intellectual disability-facial dysmorphism syndrome due to SETD5 haploinsufficiency
    MedGen: C3810406 OMIM: 615761 GeneReviews: Not available
    Compare labs

    Copy number response

    Description
    Copy number response
    Triplosensitivity

    No evidence available (Last evaluated 2014-11-06)

    ClinGen Genome Curation Page
    Haploinsufficency

    Sufficient evidence for dosage pathogenicity (Last evaluated 2014-11-06)

    ClinGen Genome Curation PagePubMed

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ10707, KIAA1757, DKFZp686J18276

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables histone H3K36 methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables histone H3K36 trimethyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3K9 methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables histone H3K9 monomethyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3K9me2 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables methylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cognition ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of transcription by RNA polymerase III IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of DNA-templated transcription elongation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of chromatin organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of synapse assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of Rpd3L-Expanded complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Set3 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of chromatin ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of euchromatin ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    histone-lysine N-methyltransferase SETD5
    Names
    SET domain-containing protein 5
    NP_001073986.1
    NP_001278972.1
    NP_001336380.1
    XP_005265358.1
    XP_011532224.1
    XP_011532230.1
    XP_011532235.1
    XP_016862260.1
    XP_016862263.1
    XP_047304422.1
    XP_047304423.1
    XP_047304424.1
    XP_047304425.1
    XP_047304426.1
    XP_047304427.1
    XP_047304428.1
    XP_047304429.1
    XP_047304430.1
    XP_047304431.1
    XP_047304432.1
    XP_047304433.1
    XP_047304434.1
    XP_047304435.1
    XP_047304436.1
    XP_047304437.1
    XP_047304438.1
    XP_047304439.1
    XP_047304440.1
    XP_047304441.1
    XP_047304442.1
    XP_047304443.1
    XP_047304444.1
    XP_047304445.1
    XP_047304446.1
    XP_047304447.1
    XP_047304448.1
    XP_047304449.1
    XP_047304450.1
    XP_047304451.1
    XP_047304452.1
    XP_047304453.1
    XP_047304454.1
    XP_047304455.1
    XP_047304456.1
    XP_047304457.1
    XP_047304458.1
    XP_047304459.1
    XP_047304460.1
    XP_047304461.1
    XP_047304462.1
    XP_047304463.1
    XP_047304464.1
    XP_054203082.1
    XP_054203083.1
    XP_054203084.1
    XP_054203085.1
    XP_054203086.1
    XP_054203087.1
    XP_054203088.1
    XP_054203089.1
    XP_054203090.1
    XP_054203091.1
    XP_054203092.1
    XP_054203093.1
    XP_054203094.1
    XP_054203095.1
    XP_054203096.1
    XP_054203097.1
    XP_054203098.1
    XP_054203099.1
    XP_054203100.1
    XP_054203101.1
    XP_054203102.1
    XP_054203103.1
    XP_054203104.1
    XP_054203105.1
    XP_054203106.1
    XP_054203107.1
    XP_054203108.1
    XP_054203109.1
    XP_054203110.1
    XP_054203111.1
    XP_054203112.1
    XP_054203113.1
    XP_054203114.1
    XP_054203115.1
    XP_054203116.1
    XP_054203117.1
    XP_054203118.1
    XP_054203119.1
    XP_054203120.1
    XP_054203121.1
    XP_054203122.1
    XP_054203123.1
    XP_054203124.1
    XP_054203125.1
    XP_054203126.1
    XP_054203127.1
    XP_054203128.1
    XP_054203129.1
    XP_054203130.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_034132.1 RefSeqGene

      Range
      4916..85455
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001080517.3NP_001073986.1  histone-lysine N-methyltransferase SETD5 isoform 1

      See identical proteins and their annotated locations for NP_001073986.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AB051544, AC018506, AI243838, AK092046, CR627408
      Consensus CDS
      CCDS46741.1
      UniProtKB/Swiss-Prot
      Q6AI17, Q8WUB6, Q9C0A6, Q9H3X4, Q9H6V7, Q9H7S3, Q9NVI9
      UniProtKB/TrEMBL
      B3KRD6
      Related
      ENSP00000385852.2, ENST00000402198.7
      Conserved Domains (1) summary
      smart00317
      Location:286395
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    2. NM_001292043.2NP_001278972.1  histone-lysine N-methyltransferase SETD5 isoform 2

      See identical proteins and their annotated locations for NP_001278972.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) contains an alternate 5' exon structure and initiates translation at a downstream start codon, compared to variant 1. The encoded protein (isoform 2) has a shorter N-terminus, compared to isoform 1. Variants 2 and 3 both encode the same isoform (2).
      Source sequence(s)
      AB051544, AC018506, AI243838, AK092046, AW021954, CR627408, DB275141
      UniProtKB/TrEMBL
      B3KRD6
      Conserved Domains (2) summary
      smart00317
      Location:188297
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      cl27032
      Location:336556
      Utp14; Utp14 protein
    3. NM_001349451.2NP_001336380.1  histone-lysine N-methyltransferase SETD5 isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) contains an alternate 5' exon structure and initiates translation at a downstream start codon, compared to variant 1. The encoded protein (isoform 2) has a shorter N-terminus, compared to isoform 1. Variants 2 and 3 both encode the same isoform (2).
      Source sequence(s)
      AC018506
      UniProtKB/TrEMBL
      B3KRD6
      Conserved Domains (2) summary
      smart00317
      Location:188297
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      cl27032
      Location:336556
      Utp14; Utp14 protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

      Range
      9397615..9478154
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047448468.1XP_047304424.1  histone-lysine N-methyltransferase SETD5 isoform X1

      UniProtKB/TrEMBL
      B3KRD6
    2. XM_047448473.1XP_047304429.1  histone-lysine N-methyltransferase SETD5 isoform X2

      UniProtKB/TrEMBL
      B3KRD6
    3. XM_047448482.1XP_047304438.1  histone-lysine N-methyltransferase SETD5 isoform X7

      UniProtKB/TrEMBL
      A0A804HKJ9, B3KRD6
    4. XM_047448487.1XP_047304443.1  histone-lysine N-methyltransferase SETD5 isoform X12

      UniProtKB/TrEMBL
      B3KRD6, E7EWN3
    5. XM_047448489.1XP_047304445.1  histone-lysine N-methyltransferase SETD5 isoform X13

      UniProtKB/TrEMBL
      B3KRD6
    6. XM_047448496.1XP_047304452.1  histone-lysine N-methyltransferase SETD5 isoform X18

      UniProtKB/Swiss-Prot
      Q6AI17, Q8WUB6, Q9C0A6, Q9H3X4, Q9H6V7, Q9H7S3, Q9NVI9
      UniProtKB/TrEMBL
      B3KRD6
    7. XM_047448474.1XP_047304430.1  histone-lysine N-methyltransferase SETD5 isoform X2

      UniProtKB/TrEMBL
      B3KRD6
    8. XM_047448481.1XP_047304437.1  histone-lysine N-methyltransferase SETD5 isoform X7

      UniProtKB/TrEMBL
      A0A804HKJ9, B3KRD6
    9. XM_047448479.1XP_047304435.1  histone-lysine N-methyltransferase SETD5 isoform X6

      UniProtKB/TrEMBL
      B3KRD6
    10. XM_047448488.1XP_047304444.1  histone-lysine N-methyltransferase SETD5 isoform X12

      UniProtKB/TrEMBL
      B3KRD6, E7EWN3
    11. XM_047448490.1XP_047304446.1  histone-lysine N-methyltransferase SETD5 isoform X13

      UniProtKB/TrEMBL
      B3KRD6
    12. XM_047448497.1XP_047304453.1  histone-lysine N-methyltransferase SETD5 isoform X18

      UniProtKB/Swiss-Prot
      Q6AI17, Q8WUB6, Q9C0A6, Q9H3X4, Q9H6V7, Q9H7S3, Q9NVI9
      UniProtKB/TrEMBL
      B3KRD6
    13. XM_047448466.1XP_047304422.1  histone-lysine N-methyltransferase SETD5 isoform X1

      UniProtKB/TrEMBL
      B3KRD6
    14. XM_047448477.1XP_047304433.1  histone-lysine N-methyltransferase SETD5 isoform X4

      UniProtKB/TrEMBL
      B3KRD6
    15. XM_047448483.1XP_047304439.1  histone-lysine N-methyltransferase SETD5 isoform X9

      UniProtKB/TrEMBL
      B3KRD6
    16. XM_047448478.1XP_047304434.1  histone-lysine N-methyltransferase SETD5 isoform X5

      UniProtKB/TrEMBL
      B3KRD6
    17. XM_047448486.1XP_047304442.1  histone-lysine N-methyltransferase SETD5 isoform X11

      UniProtKB/TrEMBL
      B3KRD6
    18. XM_047448485.1XP_047304441.1  histone-lysine N-methyltransferase SETD5 isoform X10

      UniProtKB/TrEMBL
      B3KRD6
    19. XM_047448495.1XP_047304451.1  histone-lysine N-methyltransferase SETD5 isoform X17

      UniProtKB/TrEMBL
      B3KRD6
    20. XM_047448476.1XP_047304432.1  histone-lysine N-methyltransferase SETD5 isoform X3

      UniProtKB/TrEMBL
      B3KRD6
    21. XM_011533922.2XP_011532224.1  histone-lysine N-methyltransferase SETD5 isoform X2

      See identical proteins and their annotated locations for XP_011532224.1

      UniProtKB/TrEMBL
      B3KRD6
      Conserved Domains (3) summary
      PLN02217
      Location:13531460
      PLN02217; probable pectinesterase/pectinesterase inhibitor
      COG5644
      Location:466686
      COG5644; U3 small nucleolar RNA-associated protein 14 [Function unknown]
      cd19181
      Location:298447
      SET_SETD5; SET domain (including post-SET domain) found in SET domain-containing protein 5 (SETD5) and similar proteins
    22. XM_047448480.1XP_047304436.1  histone-lysine N-methyltransferase SETD5 isoform X7

      UniProtKB/TrEMBL
      A0A804HKJ9, B3KRD6
      Related
      ENSP00000507956.1, ENST00000682536.1
    23. XM_017006771.2XP_016862260.1  histone-lysine N-methyltransferase SETD5 isoform X6

      UniProtKB/TrEMBL
      B3KRD6
      Conserved Domains (3) summary
      PLN02217
      Location:13401447
      PLN02217; probable pectinesterase/pectinesterase inhibitor
      COG5644
      Location:453673
      COG5644; U3 small nucleolar RNA-associated protein 14 [Function unknown]
      cd19181
      Location:285434
      SET_SETD5; SET domain (including post-SET domain) found in SET domain-containing protein 5 (SETD5) and similar proteins
    24. XM_005265301.2XP_005265358.1  histone-lysine N-methyltransferase SETD5 isoform X12

      UniProtKB/TrEMBL
      B3KRD6, E7EWN3
      Related
      ENSP00000384114.1, ENST00000407969.5
      Conserved Domains (3) summary
      PLN02217
      Location:13211428
      PLN02217; probable pectinesterase/pectinesterase inhibitor
      COG5644
      Location:453673
      COG5644; U3 small nucleolar RNA-associated protein 14 [Function unknown]
      cd19181
      Location:285434
      SET_SETD5; SET domain (including post-SET domain) found in SET domain-containing protein 5 (SETD5) and similar proteins
    25. XM_011533928.2XP_011532230.1  histone-lysine N-methyltransferase SETD5 isoform X8

      UniProtKB/TrEMBL
      B3KRD6
      Conserved Domains (3) summary
      PLN02217
      Location:13341441
      PLN02217; probable pectinesterase/pectinesterase inhibitor
      COG5644
      Location:447667
      COG5644; U3 small nucleolar RNA-associated protein 14 [Function unknown]
      cd19181
      Location:279428
      SET_SETD5; SET domain (including post-SET domain) found in SET domain-containing protein 5 (SETD5) and similar proteins
    26. XM_047448492.1XP_047304448.1  histone-lysine N-methyltransferase SETD5 isoform X15

      UniProtKB/TrEMBL
      B3KRD6
    27. XM_017006774.2XP_016862263.1  histone-lysine N-methyltransferase SETD5 isoform X13

      UniProtKB/TrEMBL
      B3KRD6
      Conserved Domains (3) summary
      PLN02217
      Location:13211428
      PLN02217; probable pectinesterase/pectinesterase inhibitor
      COG5644
      Location:434654
      COG5644; U3 small nucleolar RNA-associated protein 14 [Function unknown]
      cd19181
      Location:266415
      SET_SETD5; SET domain (including post-SET domain) found in SET domain-containing protein 5 (SETD5) and similar proteins
    28. XM_047448500.1XP_047304456.1  histone-lysine N-methyltransferase SETD5 isoform X22

      UniProtKB/TrEMBL
      B3KRD6
    29. XM_047448501.1XP_047304457.1  histone-lysine N-methyltransferase SETD5 isoform X23

      UniProtKB/TrEMBL
      B3KRD6
    30. XM_047448503.1XP_047304459.1  histone-lysine N-methyltransferase SETD5 isoform X25

      UniProtKB/TrEMBL
      B3KRD6
    31. XM_047448504.1XP_047304460.1  histone-lysine N-methyltransferase SETD5 isoform X26

      UniProtKB/TrEMBL
      B3KRD6
    32. XM_047448502.1XP_047304458.1  histone-lysine N-methyltransferase SETD5 isoform X24

      UniProtKB/TrEMBL
      B3KRD6
    33. XM_047448505.1XP_047304461.1  histone-lysine N-methyltransferase SETD5 isoform X27

      UniProtKB/TrEMBL
      B3KRD6
    34. XM_047448506.1XP_047304462.1  histone-lysine N-methyltransferase SETD5 isoform X28

      UniProtKB/TrEMBL
      A0A804HKJ6
      Related
      ENSP00000507953.1, ENST00000684055.1
    35. XM_047448507.1XP_047304463.1  histone-lysine N-methyltransferase SETD5 isoform X29

      UniProtKB/TrEMBL
      A0A804HKJ6
    36. XM_047448508.1XP_047304464.1  histone-lysine N-methyltransferase SETD5 isoform X30

      UniProtKB/TrEMBL
      A0A804HKJ6
    37. XM_047448491.1XP_047304447.1  histone-lysine N-methyltransferase SETD5 isoform X14

      UniProtKB/TrEMBL
      B3KRD6
    38. XM_047448470.1XP_047304426.1  histone-lysine N-methyltransferase SETD5 isoform X1

      UniProtKB/TrEMBL
      B3KRD6
    39. XM_047448469.1XP_047304425.1  histone-lysine N-methyltransferase SETD5 isoform X1

      UniProtKB/TrEMBL
      B3KRD6
    40. XM_047448484.1XP_047304440.1  histone-lysine N-methyltransferase SETD5 isoform X10

      UniProtKB/TrEMBL
      B3KRD6
    41. XM_047448494.1XP_047304450.1  histone-lysine N-methyltransferase SETD5 isoform X16

      UniProtKB/TrEMBL
      B3KRD6
    42. XM_047448498.1XP_047304454.1  histone-lysine N-methyltransferase SETD5 isoform X19

      UniProtKB/TrEMBL
      B3KRD6
    43. XM_047448472.1XP_047304428.1  histone-lysine N-methyltransferase SETD5 isoform X1

      UniProtKB/TrEMBL
      B3KRD6
    44. XM_047448475.1XP_047304431.1  histone-lysine N-methyltransferase SETD5 isoform X2

      UniProtKB/TrEMBL
      B3KRD6
    45. XM_047448467.1XP_047304423.1  histone-lysine N-methyltransferase SETD5 isoform X1

      UniProtKB/TrEMBL
      B3KRD6
    46. XM_047448493.1XP_047304449.1  histone-lysine N-methyltransferase SETD5 isoform X15

      UniProtKB/TrEMBL
      B3KRD6
    47. XM_047448471.1XP_047304427.1  histone-lysine N-methyltransferase SETD5 isoform X1

      UniProtKB/TrEMBL
      B3KRD6
    48. XM_047448499.1XP_047304455.1  histone-lysine N-methyltransferase SETD5 isoform X20

      UniProtKB/TrEMBL
      B3KRD6
    49. XM_011533933.2XP_011532235.1  histone-lysine N-methyltransferase SETD5 isoform X21

      See identical proteins and their annotated locations for XP_011532235.1

      UniProtKB/TrEMBL
      B3KRD6
      Conserved Domains (3) summary
      PLN02217
      Location:12101317
      PLN02217; probable pectinesterase/pectinesterase inhibitor
      COG5644
      Location:323543
      COG5644; U3 small nucleolar RNA-associated protein 14 [Function unknown]
      cd19181
      Location:155304
      SET_SETD5; SET domain (including post-SET domain) found in SET domain-containing protein 5 (SETD5) and similar proteins

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060927.1 Alternate T2T-CHM13v2.0

      Range
      9389553..9470070
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054347108.1XP_054203083.1  histone-lysine N-methyltransferase SETD5 isoform X1

      UniProtKB/TrEMBL
      B3KRD6
    2. XM_054347114.1XP_054203089.1  histone-lysine N-methyltransferase SETD5 isoform X2

      UniProtKB/TrEMBL
      B3KRD6
    3. XM_054347125.1XP_054203100.1  histone-lysine N-methyltransferase SETD5 isoform X7

      UniProtKB/TrEMBL
      A0A804HKJ9, B3KRD6
    4. XM_054347115.1XP_054203090.1  histone-lysine N-methyltransferase SETD5 isoform X2

      UniProtKB/TrEMBL
      B3KRD6
    5. XM_054347124.1XP_054203099.1  histone-lysine N-methyltransferase SETD5 isoform X7

      UniProtKB/TrEMBL
      A0A804HKJ9, B3KRD6
    6. XM_054347121.1XP_054203096.1  histone-lysine N-methyltransferase SETD5 isoform X6

      UniProtKB/TrEMBL
      B3KRD6
    7. XM_054347133.1XP_054203108.1  histone-lysine N-methyltransferase SETD5 isoform X12

      UniProtKB/TrEMBL
      B3KRD6, E7EWN3
    8. XM_054347135.1XP_054203110.1  histone-lysine N-methyltransferase SETD5 isoform X13

      UniProtKB/TrEMBL
      B3KRD6
    9. XM_054347143.1XP_054203118.1  histone-lysine N-methyltransferase SETD5 isoform X18

      UniProtKB/Swiss-Prot
      Q6AI17, Q8WUB6, Q9C0A6, Q9H3X4, Q9H6V7, Q9H7S3, Q9NVI9
      UniProtKB/TrEMBL
      B3KRD6
    10. XM_054347107.1XP_054203082.1  histone-lysine N-methyltransferase SETD5 isoform X1

      UniProtKB/TrEMBL
      B3KRD6
    11. XM_054347118.1XP_054203093.1  histone-lysine N-methyltransferase SETD5 isoform X4

      UniProtKB/TrEMBL
      B3KRD6
    12. XM_054347127.1XP_054203102.1  histone-lysine N-methyltransferase SETD5 isoform X9

      UniProtKB/TrEMBL
      B3KRD6
    13. XM_054347119.1XP_054203094.1  histone-lysine N-methyltransferase SETD5 isoform X5

      UniProtKB/TrEMBL
      B3KRD6
    14. XM_054347130.1XP_054203105.1  histone-lysine N-methyltransferase SETD5 isoform X11

      UniProtKB/TrEMBL
      B3KRD6
    15. XM_054347129.1XP_054203104.1  histone-lysine N-methyltransferase SETD5 isoform X10

      UniProtKB/TrEMBL
      B3KRD6
    16. XM_054347141.1XP_054203116.1  histone-lysine N-methyltransferase SETD5 isoform X17

      UniProtKB/TrEMBL
      B3KRD6
    17. XM_054347117.1XP_054203092.1  histone-lysine N-methyltransferase SETD5 isoform X3

      UniProtKB/TrEMBL
      B3KRD6
    18. XM_054347113.1XP_054203088.1  histone-lysine N-methyltransferase SETD5 isoform X2

      UniProtKB/TrEMBL
      B3KRD6
    19. XM_054347123.1XP_054203098.1  histone-lysine N-methyltransferase SETD5 isoform X7

      UniProtKB/TrEMBL
      A0A804HKJ9, B3KRD6
    20. XM_054347120.1XP_054203095.1  histone-lysine N-methyltransferase SETD5 isoform X6

      UniProtKB/TrEMBL
      B3KRD6
    21. XM_054347131.1XP_054203106.1  histone-lysine N-methyltransferase SETD5 isoform X12

      UniProtKB/TrEMBL
      B3KRD6, E7EWN3
    22. XM_054347126.1XP_054203101.1  histone-lysine N-methyltransferase SETD5 isoform X8

      UniProtKB/TrEMBL
      B3KRD6
    23. XM_054347138.1XP_054203113.1  histone-lysine N-methyltransferase SETD5 isoform X15

      UniProtKB/TrEMBL
      B3KRD6
    24. XM_054347134.1XP_054203109.1  histone-lysine N-methyltransferase SETD5 isoform X13

      UniProtKB/TrEMBL
      B3KRD6
    25. XM_054347147.1XP_054203122.1  histone-lysine N-methyltransferase SETD5 isoform X22

      UniProtKB/TrEMBL
      B3KRD6
    26. XM_054347148.1XP_054203123.1  histone-lysine N-methyltransferase SETD5 isoform X23

      UniProtKB/TrEMBL
      B3KRD6
    27. XM_054347150.1XP_054203125.1  histone-lysine N-methyltransferase SETD5 isoform X25

      UniProtKB/TrEMBL
      B3KRD6
    28. XM_054347151.1XP_054203126.1  histone-lysine N-methyltransferase SETD5 isoform X26

      UniProtKB/TrEMBL
      B3KRD6
    29. XM_054347149.1XP_054203124.1  histone-lysine N-methyltransferase SETD5 isoform X24

      UniProtKB/TrEMBL
      B3KRD6
    30. XM_054347152.1XP_054203127.1  histone-lysine N-methyltransferase SETD5 isoform X27

      UniProtKB/TrEMBL
      B3KRD6
    31. XM_054347153.1XP_054203128.1  histone-lysine N-methyltransferase SETD5 isoform X28

      UniProtKB/TrEMBL
      A0A804HKJ6
    32. XM_054347154.1XP_054203129.1  histone-lysine N-methyltransferase SETD5 isoform X29

      UniProtKB/TrEMBL
      A0A804HKJ6
    33. XM_054347155.1XP_054203130.1  histone-lysine N-methyltransferase SETD5 isoform X30

      UniProtKB/TrEMBL
      A0A804HKJ6
    34. XM_054347116.1XP_054203091.1  histone-lysine N-methyltransferase SETD5 isoform X2

      UniProtKB/TrEMBL
      B3KRD6
    35. XM_054347137.1XP_054203112.1  histone-lysine N-methyltransferase SETD5 isoform X14

      UniProtKB/TrEMBL
      B3KRD6
    36. XM_054347110.1XP_054203085.1  histone-lysine N-methyltransferase SETD5 isoform X1

      UniProtKB/TrEMBL
      B3KRD6
    37. XM_054347109.1XP_054203084.1  histone-lysine N-methyltransferase SETD5 isoform X1

      UniProtKB/TrEMBL
      B3KRD6
    38. XM_054347140.1XP_054203115.1  histone-lysine N-methyltransferase SETD5 isoform X16

      UniProtKB/TrEMBL
      B3KRD6
    39. XM_054347112.1XP_054203087.1  histone-lysine N-methyltransferase SETD5 isoform X1

      UniProtKB/TrEMBL
      B3KRD6
    40. XM_054347122.1XP_054203097.1  histone-lysine N-methyltransferase SETD5 isoform X6

      UniProtKB/TrEMBL
      B3KRD6
    41. XM_054347139.1XP_054203114.1  histone-lysine N-methyltransferase SETD5 isoform X15

      UniProtKB/TrEMBL
      B3KRD6
    42. XM_054347136.1XP_054203111.1  histone-lysine N-methyltransferase SETD5 isoform X13

      UniProtKB/TrEMBL
      B3KRD6
    43. XM_054347128.1XP_054203103.1  histone-lysine N-methyltransferase SETD5 isoform X10

      UniProtKB/TrEMBL
      B3KRD6
    44. XM_054347132.1XP_054203107.1  histone-lysine N-methyltransferase SETD5 isoform X12

      UniProtKB/TrEMBL
      B3KRD6, E7EWN3
    45. XM_054347142.1XP_054203117.1  histone-lysine N-methyltransferase SETD5 isoform X18

      UniProtKB/Swiss-Prot
      Q6AI17, Q8WUB6, Q9C0A6, Q9H3X4, Q9H6V7, Q9H7S3, Q9NVI9
      UniProtKB/TrEMBL
      B3KRD6
    46. XM_054347144.1XP_054203119.1  histone-lysine N-methyltransferase SETD5 isoform X19

      UniProtKB/TrEMBL
      B3KRD6
    47. XM_054347111.1XP_054203086.1  histone-lysine N-methyltransferase SETD5 isoform X1

      UniProtKB/TrEMBL
      B3KRD6
    48. XM_054347145.1XP_054203120.1  histone-lysine N-methyltransferase SETD5 isoform X20

      UniProtKB/TrEMBL
      B3KRD6
    49. XM_054347146.1XP_054203121.1  histone-lysine N-methyltransferase SETD5 isoform X21

      UniProtKB/TrEMBL
      B3KRD6

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_018187.2: Suppressed sequence

      Description
      NM_018187.2: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.