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    GET4 guided entry of tail-anchored proteins factor 4 [ Homo sapiens (human) ]

    Gene ID: 51608, updated on 8-Aug-2021

    Summary

    Official Symbol
    GET4provided by HGNC
    Official Full Name
    guided entry of tail-anchored proteins factor 4provided by HGNC
    Primary source
    HGNC:HGNC:21690
    See related
    Ensembl:ENSG00000239857 MIM:612056
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CEE; TRC35; CGI-20; C7orf20
    Expression
    Ubiquitous expression in testis (RPKM 20.0), adrenal (RPKM 15.8) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See GET4 in Genome Data Viewer
    Location:
    7p22.3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (876554..896436)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (916191..936073)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene protein kinase cAMP-dependent type I regulatory subunit beta Neighboring gene dynein axonemal assembly factor 5 Neighboring gene Sad1 and UNC84 domain containing 1 Neighboring gene ArfGAP with dual PH domains 1 Neighboring gene cytochrome c oxidase assembly factor COX19

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Potential readthrough

    Included gene: SUN1

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables chaperone binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of BAT3 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of BAT3 complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromosome IDA
    Inferred from Direct Assay
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     

    General protein information

    Preferred Names
    Golgi to ER traffic protein 4 homolog
    Names
    H_NH1244M04.5
    conserved edge expressed protein
    conserved edge protein
    golgi to ER traffic protein 4
    transmembrane domain recognition complex 35 kDa subunit
    transmembrane domain recognition complex, 35kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_015949.3NP_057033.2  Golgi to ER traffic protein 4 homolog

      See identical proteins and their annotated locations for NP_057033.2

      Status: VALIDATED

      Source sequence(s)
      AC073957, AL133014, BG109419, BM843540, BM980767
      Consensus CDS
      CCDS5317.1
      UniProtKB/Swiss-Prot
      Q7L5D6
      Related
      ENSP00000265857.3, ENST00000265857.8
      Conserved Domains (1) summary
      pfam04190
      Location:56302
      DUF410; Protein of unknown function (DUF410)

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

      Range
      876554..896436
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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