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    SSUH2 ssu-2 homolog [ Homo sapiens (human) ]

    Gene ID: 51066, updated on 17-Jun-2019

    Summary

    Official Symbol
    SSUH2provided by HGNC
    Official Full Name
    ssu-2 homologprovided by HGNC
    Primary source
    HGNC:HGNC:24809
    See related
    Ensembl:ENSG00000125046 MIM:617479
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SSU-2; fls485; C3orf32
    Expression
    Biased expression in testis (RPKM 1.1), small intestine (RPKM 0.7) and 8 other tissues See more
    Orthologs

    Genomic context

    See SSUH2 in Genome Data Viewer
    Location:
    3p25.3
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (8619400..8745035, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (8661086..8786721, complement)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene LMCD1 antisense RNA 1 Neighboring gene uncharacterized LOC107986010 Neighboring gene RNA, U4atac small nuclear 17, pseudogene Neighboring gene LIM and cysteine rich domains 1 Neighboring gene uncharacterized LOC107986009 Neighboring gene long intergenic non-protein coding RNA 312 Neighboring gene olfactory receptor family 7 subfamily E member 122 pseudogene Neighboring gene caveolin 3 Neighboring gene uncharacterized LOC107986061 Neighboring gene oxytocin receptor

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • FLJ35706, AC087859.1

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    odontogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    protein SSUH2 homolog
    Names
    protein ssu-2 homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001256748.2NP_001243677.1  protein SSUH2 homolog isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AA622964, AK225925, AK300175
      Consensus CDS
      CCDS58815.1
      UniProtKB/Swiss-Prot
      Q9Y2M2
      Related
      ENSP00000439378.1, ENST00000544814.5
      Conserved Domains (1) summary
      cd10719
      Location:177244
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    2. NM_001256749.2NP_001243678.1  protein SSUH2 homolog isoform 2

      See identical proteins and their annotated locations for NP_001243678.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AA622964, AC034187, AK225925, BC052614, DB010779
      UniProtKB/Swiss-Prot
      Q9Y2M2
      Conserved Domains (1) summary
      cl21539
      Location:104171
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    3. NM_015931.3NP_057015.1  protein SSUH2 homolog isoform 3

      See identical proteins and their annotated locations for NP_057015.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, uses an alternate splice site and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) is shorter and has a distinct N-terminus, compared to isoform 1.
      Source sequence(s)
      AA622964, AB024705, AC034187, AK225925, DB010779
      Consensus CDS
      CCDS2568.1
      UniProtKB/Swiss-Prot
      Q9Y2M2
      UniProtKB/TrEMBL
      A0A024R2D2
      Related
      ENSP00000339150.3, ENST00000341795.7
      Conserved Domains (1) summary
      cl21539
      Location:155222
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40

    RNA

    1. NR_046358.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) includes an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AA622964, AC034187, AK057972, AK300175
      Related
      ENST00000413305.5

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

      Range
      8619400..8745035 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017006530.1XP_016862019.1  protein SSUH2 homolog isoform X10

    2. XM_017006531.1XP_016862020.1  protein SSUH2 homolog isoform X10

    3. XM_017006515.1XP_016862004.1  protein SSUH2 homolog isoform X2

      Conserved Domains (1) summary
      cd10719
      Location:360427
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    4. XM_017006523.1XP_016862012.1  protein SSUH2 homolog isoform X6

    5. XM_017006524.1XP_016862013.1  protein SSUH2 homolog isoform X7

    6. XM_017006522.1XP_016862011.1  protein SSUH2 homolog isoform X6

    7. XM_017006521.1XP_016862010.1  protein SSUH2 homolog isoform X6

    8. XM_017006514.1XP_016862003.1  protein SSUH2 homolog isoform X2

      Conserved Domains (1) summary
      cd10719
      Location:360427
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    9. XM_017006511.1XP_016862000.1  protein SSUH2 homolog isoform X2

      Conserved Domains (1) summary
      cd10719
      Location:360427
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    10. XM_017006538.1XP_016862027.1  protein SSUH2 homolog isoform X17

      UniProtKB/Swiss-Prot
      Q9Y2M2
      UniProtKB/TrEMBL
      A0A024R2D2
      Related
      ENSP00000324551.4, ENST00000317371.8
      Conserved Domains (1) summary
      cl21539
      Location:155222
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    11. XM_017006525.1XP_016862014.1  protein SSUH2 homolog isoform X8

    12. XM_017006527.1XP_016862016.1  protein SSUH2 homolog isoform X10

    13. XM_011533774.1XP_011532076.1  protein SSUH2 homolog isoform X2

      Conserved Domains (1) summary
      cd10719
      Location:360427
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    14. XM_017006534.1XP_016862023.1  protein SSUH2 homolog isoform X13

    15. XM_017006533.1XP_016862022.1  protein SSUH2 homolog isoform X12

    16. XM_017006518.1XP_016862007.1  protein SSUH2 homolog isoform X3

    17. XM_017006512.1XP_016862001.1  protein SSUH2 homolog isoform X2

      Conserved Domains (1) summary
      cd10719
      Location:360427
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    18. XM_017006513.1XP_016862002.1  protein SSUH2 homolog isoform X2

      Conserved Domains (1) summary
      cd10719
      Location:360427
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    19. XM_017006528.1XP_016862017.1  protein SSUH2 homolog isoform X10

    20. XM_017006526.1XP_016862015.1  protein SSUH2 homolog isoform X9

    21. XM_017006517.1XP_016862006.1  protein SSUH2 homolog isoform X2

      Conserved Domains (1) summary
      cd10719
      Location:360427
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    22. XM_017006520.1XP_016862009.1  protein SSUH2 homolog isoform X5

    23. XM_017006529.1XP_016862018.1  protein SSUH2 homolog isoform X10

    24. XM_017006510.1XP_016861999.1  protein SSUH2 homolog isoform X1

    25. XM_017006519.1XP_016862008.1  protein SSUH2 homolog isoform X4

    26. XM_017006540.1XP_016862029.1  protein SSUH2 homolog isoform X17

      UniProtKB/Swiss-Prot
      Q9Y2M2
      UniProtKB/TrEMBL
      A0A024R2D2
      Conserved Domains (1) summary
      cl21539
      Location:155222
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    27. XM_017006516.1XP_016862005.1  protein SSUH2 homolog isoform X2

      Conserved Domains (1) summary
      cd10719
      Location:360427
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    28. XM_017006539.1XP_016862028.1  protein SSUH2 homolog isoform X17

      UniProtKB/Swiss-Prot
      Q9Y2M2
      UniProtKB/TrEMBL
      A0A024R2D2
      Related
      ENSP00000410757.1, ENST00000415132.5
      Conserved Domains (1) summary
      cl21539
      Location:155222
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    29. XM_017006542.1XP_016862031.1  protein SSUH2 homolog isoform X17

      UniProtKB/Swiss-Prot
      Q9Y2M2
      UniProtKB/TrEMBL
      A0A024R2D2
      Conserved Domains (1) summary
      cl21539
      Location:155222
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    30. XM_017006541.1XP_016862030.1  protein SSUH2 homolog isoform X17

      UniProtKB/Swiss-Prot
      Q9Y2M2
      UniProtKB/TrEMBL
      A0A024R2D2
      Conserved Domains (1) summary
      cl21539
      Location:155222
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    31. XM_017006532.1XP_016862021.1  protein SSUH2 homolog isoform X11

    32. XM_017006535.1XP_016862024.1  protein SSUH2 homolog isoform X14

    33. XM_017006536.2XP_016862025.1  protein SSUH2 homolog isoform X15

    34. XM_017006537.1XP_016862026.1  protein SSUH2 homolog isoform X16

    RNA

    1. XR_001740162.1 RNA Sequence

    2. XR_001740163.1 RNA Sequence

    3. XR_001740164.1 RNA Sequence

    4. XR_001740165.1 RNA Sequence

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