Cd36l1 CD36 molecule like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 499985, updated on 10-Feb-2026

Summary

Go to the top of the page Help

Official Symbol: Cd36l1provided by RGD
Official Full Name: CD36 molecule like 1provided by RGD
Primary source: RGD:1565355
See related: Ensembl:ENSRNOG00000005906 AllianceGenome:RGD:1565355
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1565355
Summary: Enables scavenger receptor activity; thrombospondin receptor activity; and transforming growth factor beta binding activity. Involved in several processes, including amyloid-beta clearance by cellular catabolic process; energy homeostasis; and receptor-mediated endocytosis. Located in brush border membrane and cell surface. [provided by Alliance of Genome Resources, Jul 2025]
Expression: Biased expression in Heart (RPKM 3132.9), Spleen (RPKM 2146.6) and 6 other tissues See more
: Try the new Gene page
Try the new Transcripts and proteins table

Genomic context

Go to the top of the page Help

See Cd36l1 in Genome Data Viewer

Location:: 4q11

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (18316806..18357863)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (17424749..17465808)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (14071705..14112330)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables Toll-like receptor binding	ISO Inferred from Sequence Orthology more info
enables amyloid-beta binding	ISO Inferred from Sequence Orthology more info
enables cargo receptor activity	ISO Inferred from Sequence Orthology more info
enables high-density lipoprotein particle binding	ISO Inferred from Sequence Orthology more info
enables lipid binding	ISO Inferred from Sequence Orthology more info
enables lipoprotein particle binding	ISO Inferred from Sequence Orthology more info
enables lipoteichoic acid immune receptor activity	ISO Inferred from Sequence Orthology more info
enables long-chain fatty acid transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
enables low-density lipoprotein particle binding	ISO Inferred from Sequence Orthology more info
enables low-density lipoprotein particle receptor activity	ISO Inferred from Sequence Orthology more info
enables oleate transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
enables oleic acid binding	IDA Inferred from Direct Assay more info	PubMed
enables oxidised low-density lipoprotein particle receptor activity	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein-containing complex binding	ISO Inferred from Sequence Orthology more info
enables scavenger receptor activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables scavenger receptor activity	ISO Inferred from Sequence Orthology more info
enables short-chain fatty acid transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
enables thrombospondin receptor activity	IDA Inferred from Direct Assay more info	PubMed
enables thrombospondin receptor activity	ISO Inferred from Sequence Orthology more info
enables transforming growth factor beta binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in amyloid fibril formation	ISO Inferred from Sequence Orthology more info
involved_in amyloid fibril formation	ISS Inferred from Sequence or Structural Similarity more info
involved_in amyloid-beta clearance by cellular catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in amyloid-beta clearance by cellular catabolic process	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within apoptotic cell clearance	ISO Inferred from Sequence Orthology more info
involved_in cell adhesion	IEA Inferred from Electronic Annotation more info
involved_in cell surface receptor signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in cell-cell adhesion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cellular response to amyloid-beta	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within cellular response to bacterial lipopeptide	ISO Inferred from Sequence Orthology more info
involved_in cellular response to diacyl bacterial lipopeptide	ISO Inferred from Sequence Orthology more info
involved_in cellular response to diacyl bacterial lipopeptide	ISS Inferred from Sequence or Structural Similarity more info
involved_in cellular response to hydroperoxide	ISO Inferred from Sequence Orthology more info
involved_in cellular response to insulin stimulus	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within cellular response to lipopolysaccharide	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within cellular response to lipoteichoic acid	ISO Inferred from Sequence Orthology more info
involved_in cellular response to low-density lipoprotein particle stimulus	ISO Inferred from Sequence Orthology more info
involved_in cellular response to low-density lipoprotein particle stimulus	ISS Inferred from Sequence or Structural Similarity more info
involved_in cellular response to oxidative stress	ISO Inferred from Sequence Orthology more info
involved_in cellular response to oxidised low-density lipoprotein particle stimulus	ISO Inferred from Sequence Orthology more info
involved_in cholesterol import	ISO Inferred from Sequence Orthology more info
involved_in cholesterol import	ISS Inferred from Sequence or Structural Similarity more info
involved_in cholesterol transport	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within chylomicron assembly	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within defense response to Gram-positive bacterium	ISO Inferred from Sequence Orthology more info
involved_in digestive tract development	IEP Inferred from Expression Pattern more info	PubMed
involved_in eating behavior	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in energy homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in energy homeostasis	ISO Inferred from Sequence Orthology more info
involved_in fatty acid metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in fatty acid metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in fatty acid oxidation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in fatty acid transport	IDA Inferred from Direct Assay more info	PubMed
involved_in fatty acid transport	IEP Inferred from Expression Pattern more info	PubMed
involved_in fatty acid transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in fatty acid transport	ISO Inferred from Sequence Orthology more info
involved_in inflammatory response	ISO Inferred from Sequence Orthology more info
involved_in intestinal absorption	ISO Inferred from Sequence Orthology more info
involved_in intestinal absorption	ISS Inferred from Sequence or Structural Similarity more info
involved_in intestinal cholesterol absorption	ISO Inferred from Sequence Orthology more info
involved_in intestinal cholesterol absorption	ISS Inferred from Sequence or Structural Similarity more info
involved_in lipid storage	ISO Inferred from Sequence Orthology more info
involved_in lipid transport	IEA Inferred from Electronic Annotation more info
involved_in lipid transport across blood-brain barrier	ISO Inferred from Sequence Orthology more info
involved_in lipoprotein transport	ISO Inferred from Sequence Orthology more info
involved_in long-chain fatty acid import across plasma membrane	ISO Inferred from Sequence Orthology more info
involved_in long-chain fatty acid import into cell	ISO Inferred from Sequence Orthology more info
involved_in long-chain fatty acid import into cell	ISS Inferred from Sequence or Structural Similarity more info
involved_in long-chain fatty acid metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in long-chain fatty acid transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in long-chain fatty acid transport	ISO Inferred from Sequence Orthology more info
involved_in low-density lipoprotein particle clearance	ISO Inferred from Sequence Orthology more info
involved_in low-density lipoprotein particle mediated signaling	ISO Inferred from Sequence Orthology more info
involved_in maternal placenta development	IEP Inferred from Expression Pattern more info	PubMed
involved_in negative regulation of angiogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of angiogenesis	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of gene expression	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of protein import into nucleus	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of systemic arterial blood pressure	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in nitric oxide-cGMP-mediated signaling	ISO Inferred from Sequence Orthology more info
involved_in oxidised low-density lipoprotein particle clearance	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within phagocytosis, recognition	ISO Inferred from Sequence Orthology more info
involved_in plasma lipoprotein particle clearance	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of ERK1 and ERK2 cascade	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of MAPK cascade	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of NLRP3 inflammasome complex assembly	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of NLRP3 inflammasome complex assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of blood coagulation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of blood microparticle formation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of canonical NF-kappaB signal transduction	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of canonical NF-kappaB signal transduction	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cell-matrix adhesion	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cholesterol storage	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cold-induced thermogenesis	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cold-induced thermogenesis	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in positive regulation of cytokine production	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of cytosolic calcium ion concentration	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cytosolic calcium ion concentration	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of gene expression	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of glycogen biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of interleukin-1 beta production	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of interleukin-1 beta production	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within positive regulation of interleukin-12 production	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of interleukin-6 production	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of macrophage cytokine production	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of macrophage derived foam cell differentiation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of nitric oxide biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of phagocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of phagocytosis, engulfment	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of reactive oxygen species biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of reactive oxygen species metabolic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of toll-like receptor 4 signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of triglyceride metabolic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within positive regulation of tumor necrosis factor production	ISO Inferred from Sequence Orthology more info
involved_in receptor internalization	ISO Inferred from Sequence Orthology more info
involved_in receptor internalization	ISS Inferred from Sequence or Structural Similarity more info
involved_in receptor-mediated endocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in receptor-mediated endocytosis	ISO Inferred from Sequence Orthology more info
involved_in regulation of action potential	ISO Inferred from Sequence Orthology more info
involved_in regulation of protein-containing complex assembly	ISO Inferred from Sequence Orthology more info
involved_in regulation of removal of superoxide radicals	ISO Inferred from Sequence Orthology more info
involved_in regulation of toll-like receptor signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in response to activity	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to bacterium	ISO Inferred from Sequence Orthology more info
involved_in response to estradiol	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to fatty acid	IDA Inferred from Direct Assay more info	PubMed
involved_in response to fatty acid	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to fatty acid	ISO Inferred from Sequence Orthology more info
involved_in response to growth hormone	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to linoleic acid	ISO Inferred from Sequence Orthology more info
involved_in response to linoleic acid	ISS Inferred from Sequence or Structural Similarity more info
involved_in response to lipid	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to lipid	ISO Inferred from Sequence Orthology more info
involved_in response to mechanical stimulus	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to nutrient	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to stilbenoid	ISO Inferred from Sequence Orthology more info
involved_in response to vitamin B3	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to xenobiotic stimulus	IEP Inferred from Expression Pattern more info	PubMed
involved_in sensory perception of taste	ISO Inferred from Sequence Orthology more info
involved_in sensory perception of taste	ISS Inferred from Sequence or Structural Similarity more info
involved_in short-chain fatty acid transport	ISO Inferred from Sequence Orthology more info
involved_in triglyceride metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in triglyceride transport	ISO Inferred from Sequence Orthology more info
involved_in triglyceride transport	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
located_in Golgi apparatus	ISS Inferred from Sequence or Structural Similarity more info
located_in apical part of cell	IDA Inferred from Direct Assay more info	PubMed
located_in apical part of cell	ISO Inferred from Sequence Orthology more info
located_in apical plasma membrane	IEA Inferred from Electronic Annotation more info
located_in brush border membrane	IDA Inferred from Direct Assay more info	PubMed
located_in brush border membrane	ISO Inferred from Sequence Orthology more info
located_in caveola	IDA Inferred from Direct Assay more info	PubMed
located_in cell periphery	ISO Inferred from Sequence Orthology more info
located_in cell surface	IDA Inferred from Direct Assay more info	PubMed
located_in cell surface	ISO Inferred from Sequence Orthology more info
located_in external side of plasma membrane	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	ISO Inferred from Sequence Orthology more info
located_in membrane raft	IEA Inferred from Electronic Annotation more info
located_in membrane raft	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
part_of protein-containing complex	IDA Inferred from Direct Assay more info	PubMed
part_of receptor complex	ISO Inferred from Sequence Orthology more info
located_in sarcolemma	IDA Inferred from Direct Assay more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: CD36 molecule like 1

Names: Cd36 antigen-like; fatty acid transporter; platelet glycoprotein 4-like

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.