Format

Send to:

Choose Destination
    • Showing Current items.

    KPRP keratinocyte proline rich protein [ Homo sapiens (human) ]

    Gene ID: 448834, updated on 17-Jun-2019

    Summary

    Official Symbol
    KPRPprovided by HGNC
    Official Full Name
    keratinocyte proline rich proteinprovided by HGNC
    Primary source
    HGNC:HGNC:31823
    See related
    Ensembl:ENSG00000203786 MIM:613260
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C1orf45
    Summary
    This gene encodes a proline-rich skin protein possibly involved in keratinocyte differentiation. [provided by RefSeq, Jul 2016]
    Expression
    Restricted expression toward skin (RPKM 105.2) See more
    Orthologs

    Genomic context

    See KPRP in Genome Data Viewer
    Location:
    1q21.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (152758025..152762053)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (152730506..152734529)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene late cornified envelope pseudogene 2 Neighboring gene late cornified envelope pseudogene 1 Neighboring gene late cornified envelope 1F Neighboring gene late cornified envelope 1E

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular exosome HDA PubMed 

    General protein information

    Preferred Names
    keratinocyte proline-rich protein
    Names
    keratinocyte expressed, proline-rich protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_051190.1 RefSeqGene

      Range
      5001..9024
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001025231.2NP_001020402.1  keratinocyte proline-rich protein

      See identical proteins and their annotated locations for NP_001020402.1

      Status: REVIEWED

      Source sequence(s)
      AL353779
      Consensus CDS
      CCDS30862.1
      UniProtKB/Swiss-Prot
      Q5T749
      Related
      ENSP00000475216.1, ENST00000606109.1
      Conserved Domains (1) summary
      PHA03247
      Location:250534
      PHA03247; large tegument protein UL36; Provisional

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      152758025..152762053
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011509571.1XP_011507873.1  keratinocyte proline-rich protein isoform X1

      See identical proteins and their annotated locations for XP_011507873.1

      UniProtKB/Swiss-Prot
      Q5T749
      Conserved Domains (1) summary
      PHA03247
      Location:250534
      PHA03247; large tegument protein UL36; Provisional
    Support Center