Format

Send to:

Choose Destination
    • Showing Current items.

    ETV3L ETS variant 3 like [ Homo sapiens (human) ]

    Gene ID: 440695, updated on 17-Jun-2019

    Summary

    Official Symbol
    ETV3Lprovided by HGNC
    Official Full Name
    ETS variant 3 likeprovided by HGNC
    Primary source
    HGNC:HGNC:33834
    See related
    Ensembl:ENSG00000253831
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Low expression observed in reference dataset See more
    Orthologs

    Genomic context

    See ETV3L in Genome Data Viewer
    Location:
    1q23.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (157092043..157112832, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (157061835..157069600, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene SMU1, DNA replication regulator and spliceosomal factor pseudogene Neighboring gene keratin 8 pseudogene 45 Neighboring gene ETS variant 3 Neighboring gene CYCS pseudogene 52 Neighboring gene uncharacterized LOC107985211

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Phenotypes

    NHGRI GWAS Catalog

    Description
    Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.
    NHGRI GWA Catalog

    General gene information

    Homology

    Clone Names

    • FLJ16478

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
     
    sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    ETS translocation variant 3-like protein
    Names
    ets variant 3-like
    ets variant gene 3-like

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004341.2NP_001004341.1  ETS translocation variant 3-like protein

      See identical proteins and their annotated locations for NP_001004341.1

      Status: VALIDATED

      Source sequence(s)
      AA723297, AK131392, AL157713
      Consensus CDS
      CCDS30893.1
      UniProtKB/Swiss-Prot
      Q6ZN32
      Related
      ENSP00000430271.1, ENST00000454449.3
      Conserved Domains (1) summary
      smart00413
      Location:38124
      ETS; erythroblast transformation specific domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      157092043..157112832 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024447166.1XP_024302934.1  ETS translocation variant 3-like protein isoform X1

      Conserved Domains (1) summary
      smart00413
      Location:38124
      ETS; erythroblast transformation specific domain
    Support Center