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    BCL2L15 BCL2 like 15 [ Homo sapiens (human) ]

    Gene ID: 440603, updated on 17-Jun-2019

    Summary

    Official Symbol
    BCL2L15provided by HGNC
    Official Full Name
    BCL2 like 15provided by HGNC
    Primary source
    HGNC:HGNC:33624
    See related
    Ensembl:ENSG00000188761
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    Bfk; C1orf178
    Expression
    Biased expression in duodenum (RPKM 22.4), small intestine (RPKM 18.2) and 5 other tissues See more
    Orthologs

    Genomic context

    See BCL2L15 in Genome Data Viewer
    Location:
    1p13.2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (113876816..113887581, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (114419436..114430230, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene round spermatid basic protein 1 Neighboring gene AP4B1 antisense RNA 1 Neighboring gene protein tyrosine phosphatase non-receptor type 22 Neighboring gene adaptor related protein complex 4 subunit beta 1 Neighboring gene GATA motif-containing MPRA enhancer 196 Neighboring gene DNA cross-link repair 1B

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ22588

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    bcl-2-like protein 15
    Names
    bcl2-L-15
    pro-apoptotic Bcl-2 protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001010922.3NP_001010922.1  bcl-2-like protein 15

      See identical proteins and their annotated locations for NP_001010922.1

      Status: VALIDATED

      Source sequence(s)
      AI821052, AL137856, AY265861, BX116361
      Consensus CDS
      CCDS30809.1
      UniProtKB/Swiss-Prot
      Q5TBC7
      UniProtKB/TrEMBL
      Q53EI7
      Related
      ENSP00000376992.3, ENST00000393316.8

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      113876816..113887581 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001029944.1: Suppressed sequence

      Description
      NM_001029944.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    2. NM_001029945.1: Suppressed sequence

      Description
      NM_001029945.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    3. NM_001029946.1: Suppressed sequence

      Description
      NM_001029946.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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