Format

Send to:

Choose Destination
    • Showing Current items.

    ALKAL1 ALK and LTK ligand 1 [ Homo sapiens (human) ]

    Gene ID: 389658, updated on 17-Jun-2019

    Summary

    Official Symbol
    ALKAL1provided by HGNC
    Official Full Name
    ALK and LTK ligand 1provided by HGNC
    Primary source
    HGNC:HGNC:33775
    See related
    Ensembl:ENSG00000196711
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    AUGA; AUGB; FAM150A; UNQ9433
    Expression
    Biased expression in gall bladder (RPKM 1.3), thyroid (RPKM 1.1) and 7 other tissues See more
    Orthologs

    Genomic context

    See ALKAL1 in Genome Data Viewer
    Location:
    8q11.23
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (52534037..52565430, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (53446597..53478021, complement)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene ST18 C2H2C-type zinc finger transcription factor Neighboring gene ribosomal protein L34 pseudogene 17 Neighboring gene ST18-FAM150A intergenic CAGE-defined low expression enhancer Neighboring gene RB1 inducible coiled-coil 1 Neighboring gene uncharacterized LOC105375835

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • MGC163513, MGC163515

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    receptor signaling protein tyrosine kinase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    receptor tyrosine kinase binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ALK and LTK ligand 1
    Names
    AUG-beta
    RPLK9433
    augmentor beta
    augmentor-alpha
    family with sequence similarity 150 member A
    protein FAM150A

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207413.4NP_997296.1  ALK and LTK ligand 1 precursor

      See identical proteins and their annotated locations for NP_997296.1

      Status: VALIDATED

      Source sequence(s)
      AC013650, AI858920, AY358213, BP423106
      Consensus CDS
      CCDS6150.1
      UniProtKB/Swiss-Prot
      Q6UXT8
      Related
      ENSP00000351345.4, ENST00000358543.9
      Conserved Domains (1) summary
      pfam15129
      Location:58128
      FAM150; FAM150 family

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

      Range
      52534037..52565430 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center