U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    KRTAP10-8 keratin associated protein 10-8 [ Homo sapiens (human) ]

    Gene ID: 386681, updated on 7-Apr-2024

    Summary

    Official Symbol
    KRTAP10-8provided by HGNC
    Official Full Name
    keratin associated protein 10-8provided by HGNC
    Primary source
    HGNC:HGNC:20525
    See related
    Ensembl:ENSG00000187766 AllianceGenome:HGNC:20525
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    KAP10.8; KRTAP18-8; KRTAP18.8
    Summary
    Enables identical protein binding activity. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See KRTAP10-8 in Genome Data Viewer
    Location:
    21q22.3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (44612079..44612954)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (42972527..42973402)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (46031996..46032871)

    Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene thrombospondin type laminin G domain and EAR repeats Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46011233-46011980 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46011981-46012726 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46012727-46013473 Neighboring gene H3K27ac hESC enhancer GRCh37_chr21:46018864-46019624 Neighboring gene keratin associated protein 10-6 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46020385-46021145 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46021146-46021905 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46022006-46022862 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46022863-46023717 Neighboring gene keratin associated protein 10-7 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46031985-46032634 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46032635-46033283 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46036915-46037661 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46045935-46046630 Neighboring gene keratin associated protein 10-9 Neighboring gene keratin associated protein 10-10

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in keratin filament IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    keratin-associated protein 10-8
    Names
    high sulfur keratin-associated protein 10.8
    keratin associated protein 18-8
    keratin-associated protein 10.8
    keratin-associated protein 18.8

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198695.2NP_941968.2  keratin-associated protein 10-8

      See identical proteins and their annotated locations for NP_941968.2

      Status: VALIDATED

      Source sequence(s)
      AB076355, AL773602
      Consensus CDS
      CCDS13713.1
      UniProtKB/Swiss-Prot
      A0JNW4, P60410
      Related
      ENSP00000335565.2, ENST00000334662.2
      Conserved Domains (2) summary
      pfam01500
      Location:58221
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam13885
      Location:98138
      Keratin_B2_2; Keratin, high sulfur B2 protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

      Range
      44612079..44612954
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060945.1 Alternate T2T-CHM13v2.0

      Range
      42972527..42973402
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)