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    CCDC172 coiled-coil domain containing 172 [ Homo sapiens (human) ]

    Gene ID: 374355, updated on 27-Nov-2024

    Summary

    Official Symbol
    CCDC172provided by HGNC
    Official Full Name
    coiled-coil domain containing 172provided by HGNC
    Primary source
    HGNC:HGNC:30524
    See related
    Ensembl:ENSG00000182645 AllianceGenome:HGNC:30524
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C10orf96
    Summary
    Predicted to be located in sperm midpiece. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis (RPKM 5.2) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See CCDC172 in Genome Data Viewer
    Location:
    10q25.3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (116324448..116380029)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (117218440..117274006)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (118083960..118139541)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene GDNF family receptor alpha 1 Neighboring gene small nucleolar RNA, C/D box 158 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:118032883-118033720 Neighboring gene uncharacterized LOC107984273 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2854 Neighboring gene small nuclear ribonucleoprotein polypeptide G pseudogene 6 Neighboring gene pancreatic lipase related protein 3 Neighboring gene high mobility group box 3 pseudogene 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC35062

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in sperm midpiece ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 172
    Names
    UPF0628 protein C10orf96

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198515.3NP_940917.1  coiled-coil domain-containing protein 172

      See identical proteins and their annotated locations for NP_940917.1

      Status: VALIDATED

      Source sequence(s)
      AJ457798, BC044830
      Consensus CDS
      CCDS31291.1
      UniProtKB/Swiss-Prot
      P0C7W6
      Related
      ENSP00000329860.3, ENST00000333254.4
      Conserved Domains (1) summary
      cl25732
      Location:3209
      SMC_N; RecF/RecN/SMC N terminal domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      116324448..116380029
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006717820.5XP_006717883.1  coiled-coil domain-containing protein 172 isoform X2

      Conserved Domains (1) summary
      pfam04111
      Location:64176
      APG6; Autophagy protein Apg6
    2. XM_011539771.3XP_011538073.1  coiled-coil domain-containing protein 172 isoform X3

      Conserved Domains (1) summary
      COG1196
      Location:3209
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    3. XM_017016206.1XP_016871695.1  coiled-coil domain-containing protein 172 isoform X1

      UniProtKB/Swiss-Prot
      P0C7W6
      Conserved Domains (1) summary
      cl25732
      Location:3209
      SMC_N; RecF/RecN/SMC N terminal domain
    4. XM_047425192.1XP_047281148.1  coiled-coil domain-containing protein 172 isoform X4

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      117218440..117274006
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054365800.1XP_054221775.1  coiled-coil domain-containing protein 172 isoform X2

    2. XM_054365801.1XP_054221776.1  coiled-coil domain-containing protein 172 isoform X3

    3. XM_054365799.1XP_054221774.1  coiled-coil domain-containing protein 172 isoform X1

      UniProtKB/Swiss-Prot
      P0C7W6
    4. XM_054365802.1XP_054221777.1  coiled-coil domain-containing protein 172 isoform X4