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    Ms4a8 membrane spanning 4-domains A8 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361733, updated on 27-Nov-2024

    Summary

    Official Symbol
    Ms4a8provided by RGD
    Official Full Name
    membrane spanning 4-domains A8provided by RGD
    Primary source
    RGD:1309035
    See related
    EnsemblRapid:ENSRNOG00000020939 AllianceGenome:RGD:1309035
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ms4a8a; Ms4a8b
    Summary
    Predicted to be involved in cell surface receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human MS4A8 (membrane spanning 4-domains A8). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Uterus (RPKM 8.9), Lung (RPKM 4.4) and 5 other tissues See more
    Orthologs
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    Genomic context

    See Ms4a8 in Genome Data Viewer
    Location:
    1q43
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (217155557..217169151, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (207730665..207744260, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (227136154..227149748, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100910973 Neighboring gene sorting nexin 5, pseudogene 1 Neighboring gene membrane-spanning 4-domains, subfamily A, member 20 Neighboring gene membrane-spanning 4-domains, subfamily A, member 19

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    membrane-spanning 4-domains subfamily A member 8
    Names
    membrane-spanning 4-domains, subfamily A, member 8
    membrane-spanning 4-domains, subfamily A, member 8A
    membrane-spanning 4-domains, subfamily A, member 8B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108519.1NP_001101989.1  membrane-spanning 4-domains subfamily A member 8

      See identical proteins and their annotated locations for NP_001101989.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473953
      UniProtKB/TrEMBL
      A6I080, D3ZDZ2
      Related
      ENSRNOP00000062507.2, ENSRNOT00000063879.3
      Conserved Domains (1) summary
      pfam04103
      Location:71208
      CD20; CD20-like family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      217155557..217169151 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)