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    NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) [ Homo sapiens (human) ]

    Gene ID: 342897, updated on 17-Jun-2019

    Summary

    Official Symbol
    NCCRP1provided by HGNC
    Official Full Name
    non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)provided by HGNC
    Primary source
    HGNC:HGNC:33739
    See related
    Ensembl:ENSG00000188505 MIM:615901
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FBXO50; NCCRP-1
    Expression
    Biased expression in esophagus (RPKM 89.0) and skin (RPKM 44.9) See more
    Orthologs

    Genomic context

    See NCCRP1 in Genome Data Viewer
    Location:
    19q13.2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (39196964..39201884)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (39687604..39692522)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene acid phosphatase 7, tartrate resistant (putative) Neighboring gene p21 (RAC1) activated kinase 4 Neighboring gene syncollin Neighboring gene interferon lambda 3 pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    contributes_to ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    glycoprotein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    ubiquitin-dependent ERAD pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular exosome HDA PubMed 

    General protein information

    Preferred Names
    F-box only protein 50
    Names
    NCC receptor protein 1 homolog
    nonspecific cytotoxic cell receptor protein 1 homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001414.2NP_001001414.1  F-box only protein 50

      See identical proteins and their annotated locations for NP_001001414.1

      Status: VALIDATED

      Source sequence(s)
      AC011443, AK123941
      Consensus CDS
      CCDS12529.1
      UniProtKB/Swiss-Prot
      Q6ZVX7
      Related
      ENSP00000342137.3, ENST00000339852.5
      Conserved Domains (1) summary
      pfam04300
      Location:128271
      FBA; F-box associated region

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

      Range
      39196964..39201884
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011526906.3XP_011525208.1  F-box only protein 50 isoform X1

      Conserved Domains (1) summary
      pfam04300
      Location:128183
      FBA; F-box associated region
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