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    LINGO4 leucine rich repeat and Ig domain containing 4 [ Homo sapiens (human) ]

    Gene ID: 339398, updated on 17-Jun-2019

    Summary

    Official Symbol
    LINGO4provided by HGNC
    Official Full Name
    leucine rich repeat and Ig domain containing 4provided by HGNC
    Primary source
    HGNC:HGNC:31814
    See related
    Ensembl:ENSG00000213171 MIM:609794
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    LRRN6D; DAAT9248; PRO34002
    Expression
    Broad expression in adrenal (RPKM 1.2), testis (RPKM 0.4) and 16 other tissues See more
    Orthologs

    Genomic context

    See LINGO4 in Genome Data Viewer
    Location:
    1q21.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (151800264..151805442, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (151772765..151777882, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene tudor and KH domain containing Neighboring gene chloride nucleotide-sensitive channel 1A pseudogene Neighboring gene TDRKH antisense RNA 1 Neighboring gene RAR related orphan receptor C Neighboring gene C2CD4D and THEM5 antisense RNA 1 Neighboring gene C2 calcium dependent domain containing 4D

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4
    Names
    leucine-rich repeat neuronal protein 6D

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004432.3NP_001004432.1  leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4 precursor

      See identical proteins and their annotated locations for NP_001004432.1

      Status: VALIDATED

      Source sequence(s)
      AL589765, AY358115, BM716911, HY125702
      Consensus CDS
      CCDS30855.1
      UniProtKB/Swiss-Prot
      Q6UY18
      Related
      ENSP00000357810.3, ENST00000368820.3
      Conserved Domains (7) summary
      smart00013
      Location:3164
      LRRNT; Leucine rich repeat N-terminal domain
      smart00410
      Location:420501
      IG_like; Immunoglobulin like
      cd00116
      Location:87320
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00031
      Location:350362
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:86109
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:65120
      LRR_8; Leucine rich repeat
      cl11960
      Location:431501
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      151800264..151805442 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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