These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
-
NM_000038.6 → NP_000029.2 adenomatous polyposis coli protein isoform b
See identical proteins and their annotated locations for NP_000029.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. This variant also contains an alternate in-frame exon compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is longer than isoform a. Variants 2, 3, and 4 all encode the same isoform (b).
- Source sequence(s)
-
AB210001, CA313732, DA795663, M73548
- Consensus CDS
-
CCDS4107.1
- UniProtKB/Swiss-Prot
- B7Z2B6, D3DT03, P25054, Q15162, Q15163, Q93042
- UniProtKB/TrEMBL
-
A0A224ANK2
- Related
- ENSP00000257430.4, ENST00000257430.9
- Conserved Domains (17) summary
-
- smart00185
Location:649 → 689
- ARM; Armadillo/beta-catenin-like repeats
- pfam16689
Location:4 → 55
- APC_N_CC; Coiled-coil N-terminus of APC, dimerisation domain
- sd00043
Location:465 → 508
- ARM; armadillo repeat [structural motif]
- pfam05923
Location:1637 → 1660
- APC_r; APC repeat
- pfam05924
Location:2033 → 2052
- SAMP; SAMP Motif
- pfam05937
Location:2670 → 2843
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:2223 → 2568
- APC_basic; APC basic domain
- pfam11414
Location:127 → 207
- Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
- pfam16629
Location:732 → 1018
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:1036 → 1135
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1283 → 1368
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1662 → 1715
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1746 → 1839
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1873 → 1947
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- cl21727
Location:533 → 734
- VATPase_H; VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the peripheral V1 complex of V-ATPase, a heteromultimeric enzyme which uses ATP to actively transport protons into organelles and extracellular compartments. The ...
- cl25732
Location:4 → 272
- SMC_N; RecF/RecN/SMC N terminal domain
- cl25751
Location:1291 → 1701
- DUF4045; Domain of unknown function (DUF4045)
-
NM_001127510.3 → NP_001120982.1 adenomatous polyposis coli protein isoform b
See identical proteins and their annotated locations for NP_001120982.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. This variant also contains an alternate in-frame exon compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is longer than isoform a. Variants 2, 3, and 4 all encode the same isoform (b).
- Source sequence(s)
-
AB210001, CA313732, DA795663
- Consensus CDS
-
CCDS4107.1
- UniProtKB/Swiss-Prot
- B7Z2B6, D3DT03, P25054, Q15162, Q15163, Q93042
- UniProtKB/TrEMBL
-
A0A224ANK2
- Related
- ENSP00000427089.2, ENST00000508376.6
- Conserved Domains (17) summary
-
- smart00185
Location:649 → 689
- ARM; Armadillo/beta-catenin-like repeats
- pfam16689
Location:4 → 55
- APC_N_CC; Coiled-coil N-terminus of APC, dimerisation domain
- sd00043
Location:465 → 508
- ARM; armadillo repeat [structural motif]
- pfam05923
Location:1637 → 1660
- APC_r; APC repeat
- pfam05924
Location:2033 → 2052
- SAMP; SAMP Motif
- pfam05937
Location:2670 → 2843
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:2223 → 2568
- APC_basic; APC basic domain
- pfam11414
Location:127 → 207
- Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
- pfam16629
Location:732 → 1018
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:1036 → 1135
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1283 → 1368
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1662 → 1715
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1746 → 1839
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1873 → 1947
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- cl21727
Location:533 → 734
- VATPase_H; VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the peripheral V1 complex of V-ATPase, a heteromultimeric enzyme which uses ATP to actively transport protons into organelles and extracellular compartments. The ...
- cl25732
Location:4 → 272
- SMC_N; RecF/RecN/SMC N terminal domain
- cl25751
Location:1291 → 1701
- DUF4045; Domain of unknown function (DUF4045)
-
NM_001127511.3 → NP_001120983.2 adenomatous polyposis coli protein isoform a
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the shorter isoform (a).
- Source sequence(s)
-
AB210001, AC136500, AK294544, BP230350, CA313732
- UniProtKB/TrEMBL
-
A0A224AV41
- Related
- ENSP00000423224.2, ENST00000507379.6
- Conserved Domains (13) summary
-
- cd00020
Location:593 → 713
- ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
- pfam05923
Location:1619 → 1643
- APC_crr; APC cysteine-rich region
- pfam05924
Location:2016 → 2035
- SAMP; SAMP Motif
- pfam05937
Location:2652 → 2825
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:2205 → 2550
- APC_basic; APC basic domain
- pfam11414
Location:137 → 217
- Suppressor_APC; Adenomatous polyposis coli tumour suppressor protein
- pfam16629
Location:714 → 1001
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:1018 → 1117
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1265 → 1350
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1644 → 1700
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1721 → 1821
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1858 → 1929
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- sd00043
Location:447 → 490
- ARM; armadillo repeat [structural motif]
-
NM_001354895.2 → NP_001341824.1 adenomatous polyposis coli protein isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (4), as well as variants 2 and 3, encodes isoform b.
- Source sequence(s)
-
AC008575, AC136500
- Consensus CDS
-
CCDS4107.1
- UniProtKB/Swiss-Prot
- B7Z2B6, D3DT03, P25054, Q15162, Q15163, Q93042
- UniProtKB/TrEMBL
-
A0A224ANK2
- Conserved Domains (17) summary
-
- smart00185
Location:649 → 689
- ARM; Armadillo/beta-catenin-like repeats
- pfam16689
Location:4 → 55
- APC_N_CC; Coiled-coil N-terminus of APC, dimerisation domain
- sd00043
Location:465 → 508
- ARM; armadillo repeat [structural motif]
- pfam05923
Location:1637 → 1660
- APC_r; APC repeat
- pfam05924
Location:2033 → 2052
- SAMP; SAMP Motif
- pfam05937
Location:2670 → 2843
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:2223 → 2568
- APC_basic; APC basic domain
- pfam11414
Location:127 → 207
- Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
- pfam16629
Location:732 → 1018
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:1036 → 1135
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1283 → 1368
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1662 → 1715
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1746 → 1839
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1873 → 1947
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- cl21727
Location:533 → 734
- VATPase_H; VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the peripheral V1 complex of V-ATPase, a heteromultimeric enzyme which uses ATP to actively transport protons into organelles and extracellular compartments. The ...
- cl25732
Location:4 → 272
- SMC_N; RecF/RecN/SMC N terminal domain
- cl25751
Location:1291 → 1701
- DUF4045; Domain of unknown function (DUF4045)
-
NM_001354896.2 → NP_001341825.1 adenomatous polyposis coli protein isoform c
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
- A0A224ANK2, R4GMU6
- Related
- ENSP00000473355.2, ENST00000504915.3
- Conserved Domains (17) summary
-
- smart00185
Location:667 → 707
- ARM; Armadillo/beta-catenin-like repeats
- pfam00514
Location:709 → 749
- Arm; Armadillo/beta-catenin-like repeat
- pfam16689
Location:4 → 55
- APC_N_CC; Coiled-coil N-terminus of APC, dimerisation domain
- sd00043
Location:581 → 613
- ARM; armadillo repeat [structural motif]
- pfam05923
Location:1655 → 1678
- APC_r; APC repeat
- pfam05924
Location:2051 → 2070
- SAMP; SAMP Motif
- pfam05937
Location:2688 → 2861
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:2241 → 2586
- APC_basic; APC basic domain
- pfam11414
Location:127 → 207
- Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
- pfam16629
Location:750 → 1036
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:1054 → 1153
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1301 → 1386
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1680 → 1733
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1764 → 1857
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1891 → 1965
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- cl25732
Location:4 → 272
- SMC_N; RecF/RecN/SMC N terminal domain
- cl25751
Location:1309 → 1719
- DUF4045; Domain of unknown function (DUF4045)
-
NM_001354897.2 → NP_001341826.1 adenomatous polyposis coli protein isoform d
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224AV41
- Conserved Domains (15) summary
-
- smart00185
Location:659 → 699
- ARM; Armadillo/beta-catenin-like repeats
- pfam00514
Location:701 → 741
- Arm; Armadillo/beta-catenin-like repeat
- sd00043
Location:475 → 518
- ARM; armadillo repeat [structural motif]
- pfam05923
Location:1647 → 1670
- APC_r; APC repeat
- pfam05924
Location:2043 → 2062
- SAMP; SAMP Motif
- pfam05937
Location:2680 → 2853
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:2233 → 2578
- APC_basic; APC basic domain
- pfam11414
Location:137 → 217
- Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
- pfam16629
Location:742 → 1028
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:1046 → 1145
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1293 → 1378
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1672 → 1725
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1756 → 1849
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1883 → 1957
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- cl25751
Location:1301 → 1711
- DUF4045; Domain of unknown function (DUF4045)
-
NM_001354898.2 → NP_001341827.1 adenomatous polyposis coli protein isoform e
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
- Conserved Domains (15) summary
-
- smart00185
Location:624 → 664
- ARM; Armadillo/beta-catenin-like repeats
- pfam00514
Location:666 → 706
- Arm; Armadillo/beta-catenin-like repeat
- sd00043
Location:440 → 483
- ARM; armadillo repeat [structural motif]
- pfam05923
Location:1612 → 1635
- APC_r; APC repeat
- pfam05924
Location:2008 → 2027
- SAMP; SAMP Motif
- pfam05937
Location:2645 → 2818
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:2198 → 2543
- APC_basic; APC basic domain
- pfam11414
Location:102 → 182
- Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
- pfam16629
Location:707 → 993
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:1011 → 1110
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1258 → 1343
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1637 → 1690
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1721 → 1814
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1848 → 1922
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- cl25751
Location:1266 → 1676
- DUF4045; Domain of unknown function (DUF4045)
-
NM_001354899.2 → NP_001341828.1 adenomatous polyposis coli protein isoform f
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
- Conserved Domains (16) summary
-
- smart00185
Location:621 → 661
- ARM; Armadillo/beta-catenin-like repeats
- pfam00514
Location:663 → 703
- Arm; Armadillo/beta-catenin-like repeat
- pfam16689
Location:4 → 55
- APC_N_CC; Coiled-coil N-terminus of APC, dimerisation domain
- sd00043
Location:437 → 480
- ARM; armadillo repeat [structural motif]
- pfam05923
Location:1609 → 1632
- APC_r; APC repeat
- pfam05924
Location:2005 → 2024
- SAMP; SAMP Motif
- pfam05937
Location:2642 → 2815
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:2195 → 2540
- APC_basic; APC basic domain
- pfam11414
Location:127 → 207
- Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
- pfam16629
Location:704 → 990
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:1008 → 1107
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1255 → 1340
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1634 → 1687
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1718 → 1811
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1845 → 1919
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- cl25751
Location:1263 → 1673
- DUF4045; Domain of unknown function (DUF4045)
-
NM_001354900.2 → NP_001341829.1 adenomatous polyposis coli protein isoform g
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
- Conserved Domains (15) summary
-
- smart00185
Location:608 → 648
- ARM; Armadillo/beta-catenin-like repeats
- pfam00514
Location:650 → 690
- Arm; Armadillo/beta-catenin-like repeat
- sd00043
Location:522 → 554
- ARM; armadillo repeat [structural motif]
- pfam05923
Location:1596 → 1619
- APC_r; APC repeat
- pfam05924
Location:1992 → 2011
- SAMP; SAMP Motif
- pfam05937
Location:2629 → 2802
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:2182 → 2527
- APC_basic; APC basic domain
- pfam11414
Location:68 → 148
- Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
- pfam16629
Location:691 → 977
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:995 → 1094
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1242 → 1327
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1621 → 1674
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1705 → 1798
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1832 → 1906
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- cl25751
Location:1250 → 1660
- DUF4045; Domain of unknown function (DUF4045)
-
NM_001354901.2 → NP_001341830.1 adenomatous polyposis coli protein isoform h
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
- Related
- ENSP00000518940.1, ENST00000713639.1
- Conserved Domains (15) summary
-
- smart00185
Location:590 → 630
- ARM; Armadillo/beta-catenin-like repeats
- pfam00514
Location:632 → 672
- Arm; Armadillo/beta-catenin-like repeat
- sd00043
Location:406 → 449
- ARM; armadillo repeat [structural motif]
- pfam05923
Location:1578 → 1601
- APC_r; APC repeat
- pfam05924
Location:1974 → 1993
- SAMP; SAMP Motif
- pfam05937
Location:2611 → 2784
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:2164 → 2509
- APC_basic; APC basic domain
- pfam11414
Location:68 → 148
- Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
- pfam16629
Location:673 → 959
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:977 → 1076
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1224 → 1309
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1603 → 1656
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1687 → 1780
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1814 → 1888
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- cl25751
Location:1232 → 1642
- DUF4045; Domain of unknown function (DUF4045)
-
NM_001354902.2 → NP_001341831.1 adenomatous polyposis coli protein isoform i
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224AV41
- Conserved Domains (15) summary
-
- smart00185
Location:558 → 598
- ARM; Armadillo/beta-catenin-like repeats
- pfam00514
Location:600 → 640
- Arm; Armadillo/beta-catenin-like repeat
- sd00043
Location:374 → 417
- ARM; armadillo repeat [structural motif]
- pfam05923
Location:1546 → 1569
- APC_r; APC repeat
- pfam05924
Location:1942 → 1961
- SAMP; SAMP Motif
- pfam05937
Location:2579 → 2752
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:2132 → 2477
- APC_basic; APC basic domain
- pfam11414
Location:137 → 217
- Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
- pfam16629
Location:641 → 927
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:945 → 1044
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1192 → 1277
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1571 → 1624
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1655 → 1748
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1782 → 1856
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- cl25751
Location:1200 → 1610
- DUF4045; Domain of unknown function (DUF4045)
-
NM_001354903.2 → NP_001341832.1 adenomatous polyposis coli protein isoform j
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
- Conserved Domains (17) summary
-
- smart00185
Location:548 → 588
- ARM; Armadillo/beta-catenin-like repeats
- pfam00514
Location:590 → 630
- Arm; Armadillo/beta-catenin-like repeat
- pfam16689
Location:4 → 55
- APC_N_CC; Coiled-coil N-terminus of APC, dimerisation domain
- sd00043
Location:364 → 407
- ARM; armadillo repeat [structural motif]
- pfam05923
Location:1536 → 1559
- APC_r; APC repeat
- pfam05924
Location:1932 → 1951
- SAMP; SAMP Motif
- pfam05937
Location:2569 → 2742
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:2122 → 2467
- APC_basic; APC basic domain
- pfam11414
Location:127 → 207
- Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
- pfam16629
Location:631 → 917
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:935 → 1034
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1182 → 1267
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1561 → 1614
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1645 → 1738
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1772 → 1846
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- cl25732
Location:4 → 272
- SMC_N; RecF/RecN/SMC N terminal domain
- cl25751
Location:1190 → 1600
- DUF4045; Domain of unknown function (DUF4045)
-
NM_001354904.2 → NP_001341833.1 adenomatous polyposis coli protein isoform k
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
- Conserved Domains (15) summary
-
- smart00185
Location:523 → 563
- ARM; Armadillo/beta-catenin-like repeats
- pfam00514
Location:565 → 605
- Arm; Armadillo/beta-catenin-like repeat
- sd00043
Location:339 → 382
- ARM; armadillo repeat [structural motif]
- pfam05923
Location:1511 → 1534
- APC_r; APC repeat
- pfam05924
Location:1907 → 1926
- SAMP; SAMP Motif
- pfam05937
Location:2544 → 2717
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:2097 → 2442
- APC_basic; APC basic domain
- pfam11414
Location:102 → 182
- Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
- pfam16629
Location:606 → 892
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:910 → 1009
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1157 → 1242
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1536 → 1589
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1620 → 1713
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1747 → 1821
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- cl25751
Location:1165 → 1575
- DUF4045; Domain of unknown function (DUF4045)
-
NM_001354905.2 → NP_001341834.1 adenomatous polyposis coli protein isoform l
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
- Conserved Domains (15) summary
-
- smart00185
Location:489 → 529
- ARM; Armadillo/beta-catenin-like repeats
- pfam00514
Location:531 → 571
- Arm; Armadillo/beta-catenin-like repeat
- sd00043
Location:305 → 348
- ARM; armadillo repeat [structural motif]
- pfam05923
Location:1477 → 1500
- APC_r; APC repeat
- pfam05924
Location:1873 → 1892
- SAMP; SAMP Motif
- pfam05937
Location:2510 → 2683
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:2063 → 2408
- APC_basic; APC basic domain
- pfam11414
Location:68 → 148
- Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
- pfam16629
Location:572 → 858
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:876 → 975
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1123 → 1208
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1502 → 1555
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1586 → 1679
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1713 → 1787
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- cl25751
Location:1131 → 1541
- DUF4045; Domain of unknown function (DUF4045)
-
NM_001354906.2 → NP_001341835.1 adenomatous polyposis coli protein isoform m
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
- Conserved Domains (14) summary
-
- smart00185
Location:366 → 406
- ARM; Armadillo/beta-catenin-like repeats
- pfam00514
Location:408 → 448
- Arm; Armadillo/beta-catenin-like repeat
- sd00043
Location:182 → 225
- ARM; armadillo repeat [structural motif]
- pfam05923
Location:1354 → 1377
- APC_r; APC repeat
- pfam05924
Location:1750 → 1769
- SAMP; SAMP Motif
- pfam05937
Location:2387 → 2560
- EB1_binding; EB-1 Binding Domain
- pfam05956
Location:1940 → 2285
- APC_basic; APC basic domain
- pfam16629
Location:449 → 735
- Arm_APC_u3; Armadillo-associated region on APC
- pfam16630
Location:753 → 852
- APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
- pfam16633
Location:1000 → 1085
- APC_u9; Unstructured region on APC between 1st two creatine-rich regions
- pfam16634
Location:1379 → 1432
- APC_u13; Unstructured region on APC between APC_crr and SAMP
- pfam16635
Location:1463 → 1556
- APC_u14; Unstructured region on APC between SAMP and APC_crr
- pfam16636
Location:1590 → 1664
- APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
- cl25751
Location:1008 → 1418
- DUF4045; Domain of unknown function (DUF4045)
-
NM_001407446.1 → NP_001394375.1 adenomatous polyposis coli protein isoform n
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224AV41
-
NM_001407447.1 → NP_001394376.1 adenomatous polyposis coli protein isoform c
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
- A0A224ANK2, R4GMU6
-
NM_001407448.1 → NP_001394377.1 adenomatous polyposis coli protein isoform c
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
- A0A224ANK2, R4GMU6
-
NM_001407449.1 → NP_001394378.1 adenomatous polyposis coli protein isoform c
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
- A0A224ANK2, R4GMU6
-
NM_001407450.1 → NP_001394379.1 adenomatous polyposis coli protein isoform b
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/Swiss-Prot
- B7Z2B6, D3DT03, P25054, Q15162, Q15163, Q93042
- UniProtKB/TrEMBL
-
A0A224ANK2
- Related
- ENSP00000426541.2, ENST00000509732.6
-
NM_001407451.1 → NP_001394380.1 adenomatous polyposis coli protein isoform o
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
-
NM_001407452.1 → NP_001394381.1 adenomatous polyposis coli protein isoform p
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
-
NM_001407453.1 → NP_001394382.1 adenomatous polyposis coli protein isoform h
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
-
NM_001407454.1 → NP_001394383.1 adenomatous polyposis coli protein isoform q
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
-
NM_001407455.1 → NP_001394384.1 adenomatous polyposis coli protein isoform q
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
-
NM_001407456.1 → NP_001394385.1 adenomatous polyposis coli protein isoform q
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
-
NM_001407457.1 → NP_001394386.1 adenomatous polyposis coli protein isoform q
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
-
NM_001407458.1 → NP_001394387.1 adenomatous polyposis coli protein isoform j
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
-
NM_001407459.1 → NP_001394388.1 adenomatous polyposis coli protein isoform j
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
-
NM_001407460.1 → NP_001394389.1 adenomatous polyposis coli protein isoform j
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
-
NM_001407467.1 → NP_001394396.1 adenomatous polyposis coli protein isoform r
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
-
NM_001407469.1 → NP_001394398.1 adenomatous polyposis coli protein isoform r
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
-
NM_001407470.1 → NP_001394399.1 adenomatous polyposis coli protein isoform m
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
-
NM_001407471.1 → NP_001394400.1 adenomatous polyposis coli protein isoform s
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2
-
NM_001407472.1 → NP_001394401.1 adenomatous polyposis coli protein isoform s
Status: REVIEWED
- Source sequence(s)
-
AC008575, AC136500
- UniProtKB/TrEMBL
-
A0A224ANK2