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    Cdh7 cadherin 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29162, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Cdh7provided by RGD
    Official Full Name
    cadherin 7provided by RGD
    Primary source
    RGD:1306856
    See related
    Ensembl:ENSRNOG00000032490 AllianceGenome:RGD:1306856
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Cad7
    Summary
    Predicted to enable cadherin binding activity and calcium ion binding activity. Predicted to be involved in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell morphogenesis; and cell-cell junction organization. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of catenin complex. Predicted to be active in adherens junction. Orthologous to human CDH7 (cadherin 7). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward (RPKM 134.5) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cdh7 in Genome Data Viewer
    Location:
    13q11
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (27186223..27336076)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (26672058..26821571)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (31081064..31228884)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene arrestin, beta 1, pseudogene 1 Neighboring gene cyclin-dependent kinases regulatory subunit 1 pseudogene Neighboring gene U6 spliceosomal RNA Neighboring gene 40S ribosomal protein S28 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Expression study of cadherin7 and cadherin20 in the embryonic and adult rat central nervous system. Takahashi M, et al. BMC Dev Biol, 2008 Sep 19. PMID 18801203, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables beta-catenin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cadherin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in adherens junction organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell-cell adhesion mediated by cadherin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell-cell junction assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in multicellular organism development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in adherens junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of catenin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cadherin-7
    Names
    Cadherin7
    cadherin 7, type 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012737.1 → NP_001012755.1  cadherin-7 precursor

      See identical proteins and their annotated locations for NP_001012755.1

      Status: PROVISIONAL

      Source sequence(s)
      AB121031
      UniProtKB/Swiss-Prot
      Q5DWV2
      Conserved Domains (3) summary
      cd11304
      Location:157 → 258
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:73 → 151
      CA; Cadherin repeats
      pfam01049
      Location:639 → 777
      Cadherin_C; Cadherin cytoplasmic region

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      27186223..27336076
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017598763.3 → XP_017454252.1  cadherin-7 isoform X1

      UniProtKB/TrEMBL
      A6JSW4, G3V9J2
      Related
      ENSRNOP00000049491.2
      Conserved Domains (3) summary
      cd11304
      Location:157 → 258
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:73 → 151
      CA; Cadherin repeats
      pfam01049
      Location:639 → 777
      Cadherin_C; Cadherin cytoplasmic region

    2. XM_017598764.3 → XP_017454253.1  cadherin-7 isoform X1

      UniProtKB/TrEMBL
      A6JSW4, G3V9J2
      Conserved Domains (3) summary
      cd11304
      Location:157 → 258
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:73 → 151
      CA; Cadherin repeats
      pfam01049
      Location:639 → 777
      Cadherin_C; Cadherin cytoplasmic region
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5DWV2.1 GenPept UniProtKB/Swiss-Prot:Q5DWV2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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