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    GTPBP8 GTP binding protein 8 (putative) [ Homo sapiens (human) ]

    Gene ID: 29083, updated on 15-Jun-2019

    Summary

    Official Symbol
    GTPBP8provided by HGNC
    Official Full Name
    GTP binding protein 8 (putative)provided by HGNC
    Primary source
    HGNC:HGNC:25007
    See related
    Ensembl:ENSG00000163607
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HSPC135
    Expression
    Ubiquitous expression in testis (RPKM 4.6), thyroid (RPKM 3.8) and 25 other tissues See more
    Orthologs

    Genomic context

    See GTPBP8 in Genome Data Viewer
    Location:
    3q13.2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 3 NC_000003.12 (112990953..113001374)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (112709323..112720221)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene CD200R1L antisense RNA 1 Neighboring gene CD200 receptor 1 like Neighboring gene CD200 receptor 1 Neighboring gene uncharacterized LOC107986114 Neighboring gene endogenous retrovirus group K member 7 Gag polyprotein Neighboring gene nucleolus and neural progenitor protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_014170.3NP_054889.2  GTP-binding protein 8 isoform 1

      See identical proteins and their annotated locations for NP_054889.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC074044, AF161484, AI367201, BC000003, CA429378
      Consensus CDS
      CCDS33820.1
      UniProtKB/Swiss-Prot
      Q8N3Z3
      UniProtKB/TrEMBL
      Q9P025
      Related
      ENSP00000373176.2, ENST00000383678.6
      Conserved Domains (1) summary
      cd01876
      Location:112280
      YihA_EngB; YihA (EngB) GTPase family
    2. NM_138485.1NP_612494.1  GTP-binding protein 8 isoform 2

      See identical proteins and their annotated locations for NP_612494.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1, resulting in an isoform (2) that is missing an internal segment compared to isoform 1.
      Source sequence(s)
      AI367201, BI830308, BX354218, CA429378
      Consensus CDS
      CCDS33821.1
      UniProtKB/Swiss-Prot
      Q8N3Z3
      Related
      ENSP00000373175.3, ENST00000383677.7
      Conserved Domains (1) summary
      cd01876
      Location:113247
      YihA_EngB; YihA (EngB) GTPase family

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

      Range
      112990953..113001961
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001008235.1: Suppressed sequence

      Description
      NM_001008235.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    2. NM_001008236.1: Suppressed sequence

      Description
      NM_001008236.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
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