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    IGLV6-57 immunoglobulin lambda variable 6-57 [ Homo sapiens (human) ]

    Gene ID: 28778, updated on 17-Jun-2019

    Summary

    Official Symbol
    IGLV6-57provided by HGNC
    Official Full Name
    immunoglobulin lambda variable 6-57provided by HGNC
    Primary source
    HGNC:HGNC:5927
    See related
    IMGT/GENE-DB:IGLV6-57
    Gene type
    other
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    V1-22; IGLV657

    Genomic context

    See IGLV6-57 in Genome Data Viewer
    Location:
    22q11.22
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 22 NC_000022.11 (22195799..22196276)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (22550199..22550676)

    Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene immunoglobulin lambda locus Neighboring gene immunoglobulin lambda variable (V)-58 (pseudogene) Neighboring gene immunoglobulin lambda variable 11-55 (non-functional) Neighboring gene immunoglobulin lambda variable (I)-56 (pseudogene) Neighboring gene bone morphogenetic protein 6 pseudogene 1

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Other Names

    • Ig lambda chain V-VI region AR
    • amyloid lambda 6 light chain variable region PIP
    • amyloid lambda 6 light chain variable region SAR

    Clone Names

    • MGC34845

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    antigen binding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    Fc-epsilon receptor signaling pathway TAS
    Traceable Author Statement
    more info
     
    Fc-gamma receptor signaling pathway involved in phagocytosis TAS
    Traceable Author Statement
    more info
     
    complement activation TAS
    Traceable Author Statement
    more info
     
    complement activation, classical pathway TAS
    Traceable Author Statement
    more info
     
    immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    immune response NAS
    Non-traceable Author Statement
    more info
    PubMed 
    immunoglobulin production IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    leukocyte migration TAS
    Traceable Author Statement
    more info
     
    receptor-mediated endocytosis TAS
    Traceable Author Statement
    more info
     
    regulation of complement activation TAS
    Traceable Author Statement
    more info
     
    regulation of immune response TAS
    Traceable Author Statement
    more info
     
    Component Evidence Code Pubs
    extracellular region NAS
    Non-traceable Author Statement
    more info
    PubMed 
    extracellular region TAS
    Traceable Author Statement
    more info
     
    extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    immunoglobulin complex IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane TAS
    Traceable Author Statement
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_000002.1 

      Range
      174188..174665
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000022.11 Reference GRCh38.p13 Primary Assembly

      Range
      22195799..22196276
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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