Format

Send to:

Choose Destination
    • Showing Current items.

    SMR3A submaxillary gland androgen regulated protein 3A [ Homo sapiens (human) ]

    Gene ID: 26952, updated on 11-Jun-2021

    Summary

    Official Symbol
    SMR3Aprovided by HGNC
    Official Full Name
    submaxillary gland androgen regulated protein 3Aprovided by HGNC
    Primary source
    HGNC:HGNC:19216
    See related
    Ensembl:ENSG00000109208 MIM:618340
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PBI; P-B1; PRL5; PROL5
    Expression
    Restricted expression toward salivary gland (RPKM 1417.1) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See SMR3A in Genome Data Viewer
    Location:
    4q13.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (70360760..70367158)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (71226477..71232875)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene casein kappa Neighboring gene calcium binding protein, spermatid associated 1 Neighboring gene submaxillary gland androgen regulated protein 3B Neighboring gene opiorphin prepropeptide

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of sensory perception of pain IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    submaxillary gland androgen-regulated protein 3A
    Names
    proline rich 5 (salivary)
    proline- rich protein 5
    proline-rich protein PBI
    protein homologous to salivary proline-rich protein P-B
    submaxillary gland androgen regulated protein 3 homolog A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012390.4NP_036522.3  submaxillary gland androgen-regulated protein 3A precursor

      See identical proteins and their annotated locations for NP_036522.3

      Status: VALIDATED

      Source sequence(s)
      AC106884, CA946421, CD722957
      Consensus CDS
      CCDS34000.1
      UniProtKB/Swiss-Prot
      Q99954
      Related
      ENSP00000226460.4, ENST00000226460.5
      Conserved Domains (1) summary
      pfam15621
      Location:163
      PROL5-SMR; Proline-rich submaxillary gland androgen-regulated family

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

      Range
      70360760..70367158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017008021.1XP_016863510.1  submaxillary gland androgen-regulated protein 3A isoform X1

      UniProtKB/Swiss-Prot
      Q99954
      Conserved Domains (1) summary
      pfam15621
      Location:163
      PROL5-SMR; Proline-rich submaxillary gland androgen-regulated family
    Support Center