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    SPIDR scaffold protein involved in DNA repair [ Homo sapiens (human) ]

    Gene ID: 23514, updated on 17-Jun-2019

    Summary

    Official Symbol
    SPIDRprovided by HGNC
    Official Full Name
    scaffold protein involved in DNA repairprovided by HGNC
    Primary source
    HGNC:HGNC:28971
    See related
    Ensembl:ENSG00000164808 MIM:615384
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    KIAA0146
    Expression
    Ubiquitous expression in lung (RPKM 8.1), thyroid (RPKM 7.9) and 25 other tissues See more
    Orthologs

    Genomic context

    See SPIDR in Genome Data Viewer
    Location:
    8q11.21
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (47260878..47736306)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (48173489..48648563)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene ATPase H+ transporting V1 subunit G1 pseudogene 2 Neighboring gene immunoglobulin lambda variable 8/OR8-1 (pseudogene) Neighboring gene uncharacterized LOC107986940 Neighboring gene NSFL1 cofactor pseudogene Neighboring gene ribosomal protein S4 Y-linked 2 pseudogene Neighboring gene ubiquitin conjugating enzyme E2 N pseudogene Neighboring gene RNA, U6 small nuclear 665, pseudogene Neighboring gene CCAAT enhancer binding protein delta Neighboring gene protein kinase, DNA-activated, catalytic subunit Neighboring gene uncharacterized LOC105375818

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • DNA Double-Strand Break Repair, organism-specific biosystem (from REACTOME)
      DNA Double-Strand Break Repair, organism-specific biosystemNumerous types of DNA damage can occur within a cell due to the endogenous production of oxygen free radicals, normal alkylation reactions, or exposure to exogenous radiations and chemicals. Double-s...
    • DNA Repair, organism-specific biosystem (from REACTOME)
      DNA Repair, organism-specific biosystemDNA repair is a phenomenal multi-enzyme, multi-pathway system required to ensure the integrity of the cellular genome. Living organisms are constantly exposed to harmful metabolic by-products, enviro...
    • HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA), organism-specific biosystem (from REACTOME)
      HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA), organism-specific biosystemHomology directed repair (HDR) of replication-independent DNA double strand breaks (DSBs) via homologous recombination repair (HRR) or single strand annealing (SSA) requires the activation of ATM fol...
    • HDR through Homologous Recombination (HRR), organism-specific biosystem (from REACTOME)
      HDR through Homologous Recombination (HRR), organism-specific biosystemHomology directed repair (HDR) through homologous recombination is known as homologous recombination repair (HRR). HRR occurs after extensive resection of DNA double strand break (DSB) ends, which cr...
    • Homology Directed Repair, organism-specific biosystem (from REACTOME)
      Homology Directed Repair, organism-specific biosystemHomology directed repair (HDR) of DNA double strand breaks (DSBs) requires resection of DNA DSB ends. Resection creates 3'-ssDNA overhangs which then anneal with a homologous DNA sequence. This homol...
    • Resolution of D-Loop Structures, organism-specific biosystem (from REACTOME)
      Resolution of D-Loop Structures, organism-specific biosystemOnce repair synthesis has occurred, the D-loop structure may be resolved either through Holliday junction intermediates or through synthesis-dependent strand-annealing (SDSA) (Prado and Aguilera 2003...
    • Resolution of D-loop Structures through Holliday Junction Intermediates, organism-specific biosystem (from REACTOME)
      Resolution of D-loop Structures through Holliday Junction Intermediates, organism-specific biosystemD-loops generated after strand invasion and DNA repair synthesis during homologous recombination repair (HRR) can be resolved through Holliday junction intermediates.A D-loop can be cleaved by the co...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ35017, KIAA0146

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    nuclear chromosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear chromosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    nucleoplasm TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    DNA repair-scaffolding protein
    Names
    scaffolding protein involved in DNA repair

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080394.4NP_001073863.1  DNA repair-scaffolding protein isoform 1

      See identical proteins and their annotated locations for NP_001073863.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC023991, AC233269, BM981420, D63480
      Consensus CDS
      CCDS43737.1
      UniProtKB/Swiss-Prot
      Q14159
      Related
      ENSP00000297423.4, ENST00000297423.8
      Conserved Domains (2) summary
      pfam14950
      Location:11369
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:521905
      DUF4503; Domain of unknown function (DUF4503)
    2. NM_001282916.1NP_001269845.1  DNA repair-scaffolding protein isoform 2

      See identical proteins and their annotated locations for NP_001269845.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region which results in the use of a downstream start codon, compred to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus, compared to isoform 1.
      Source sequence(s)
      AC023991, AC233269, AK294275, BM981420
      Consensus CDS
      CCDS64891.1
      UniProtKB/Swiss-Prot
      Q14159
      Related
      ENSP00000444061.1, ENST00000541342.2
      Conserved Domains (2) summary
      pfam14950
      Location:25299
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:451835
      DUF4503; Domain of unknown function (DUF4503)
    3. NM_001282919.1NP_001269848.1  DNA repair-scaffolding protein isoform 3

      See identical proteins and their annotated locations for NP_001269848.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice site in the 5' coding and lacks an exon in the 3' coding region. These differences cause translation initiation at a downstream AUG and a frameshift in the 3' coding egion . The resulting isoform (3) is shorter and has a distinct N-and C-termini, compared to isoform 1.
      Source sequence(s)
      AK303579, BM981420, HY012281
      Consensus CDS
      CCDS64890.1
      UniProtKB/Swiss-Prot
      Q14159
      Related
      ENSP00000429487.1, ENST00000518074.5
      Conserved Domains (2) summary
      pfam14950
      Location:3309
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:461790
      DUF4503; Domain of unknown function (DUF4503)
    4. NM_001352931.1NP_001339860.1  DNA repair-scaffolding protein isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:11369
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:521850
      DUF4503; Domain of unknown function (DUF4503)
    5. NM_001352932.1NP_001339861.1  DNA repair-scaffolding protein isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:11329
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:481865
      DUF4503; Domain of unknown function (DUF4503)
    6. NM_001352933.1NP_001339862.1  DNA repair-scaffolding protein isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:3309
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:461845
      DUF4503; Domain of unknown function (DUF4503)
    7. NM_001352934.1NP_001339863.1  DNA repair-scaffolding protein isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:11369
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:521814
      DUF4503; Domain of unknown function (DUF4503)
    8. NM_001352935.1NP_001339864.1  DNA repair-scaffolding protein isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:25299
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:451780
      DUF4503; Domain of unknown function (DUF4503)
    9. NM_001352936.1NP_001339865.1  DNA repair-scaffolding protein isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:25299
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:451710
      DUF4503; Domain of unknown function (DUF4503)
    10. NM_001352937.1NP_001339866.1  DNA repair-scaffolding protein isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:3309
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:461754
      DUF4503; Domain of unknown function (DUF4503)
    11. NM_001352938.1NP_001339867.1  DNA repair-scaffolding protein isoform 12

      Status: VALIDATED

      Description
      Transcript Variant: This variant (13), as well as variants 14 and 15, encodes isoform 12.
      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:11205
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:357741
      DUF4503; Domain of unknown function (DUF4503)
    12. NM_001352939.1NP_001339868.1  DNA repair-scaffolding protein isoform 12

      Status: VALIDATED

      Description
      Transcript Variant: This variant (14), as well as variants 13 and 15, encodes isoform 12.
      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:11205
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:357741
      DUF4503; Domain of unknown function (DUF4503)
    13. NM_001352940.1NP_001339869.1  DNA repair-scaffolding protein isoform 12

      Status: VALIDATED

      Description
      Transcript Variant: This variant (15), as well as variants 13 and 14, encodes isoform 12.
      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:11205
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:357741
      DUF4503; Domain of unknown function (DUF4503)
    14. NM_001352941.1NP_001339870.1  DNA repair-scaffolding protein isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:11197
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:349733
      DUF4503; Domain of unknown function (DUF4503)
    15. NM_001352942.1NP_001339871.1  DNA repair-scaffolding protein isoform 14

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:1150
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:302686
      DUF4503; Domain of unknown function (DUF4503)
    16. NM_001352943.1NP_001339872.1  DNA repair-scaffolding protein isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:11205
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:357616
      DUF4503; Domain of unknown function (DUF4503)
    17. NM_001352944.1NP_001339873.1  DNA repair-scaffolding protein isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:11197
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:349608
      DUF4503; Domain of unknown function (DUF4503)
    18. NM_001352945.1NP_001339874.1  DNA repair-scaffolding protein isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:43127
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:279663
      DUF4503; Domain of unknown function (DUF4503)
    19. NM_001352946.1NP_001339875.1  DNA repair-scaffolding protein isoform 18

      Status: VALIDATED

      Description
      Transcript Variant: This variant (21), as well as variants 22 and 23, encodes isoform 18.
      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:5119
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:271655
      DUF4503; Domain of unknown function (DUF4503)
    20. NM_001352947.1NP_001339876.1  DNA repair-scaffolding protein isoform 18

      Status: VALIDATED

      Description
      Transcript Variant: This variant (22), as well as variants 21 and 23, encodes isoform 18.
      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:5119
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:271655
      DUF4503; Domain of unknown function (DUF4503)
    21. NM_001352948.1NP_001339877.1  DNA repair-scaffolding protein isoform 18

      Status: VALIDATED

      Description
      Transcript Variant: This variant (23), as well as variants 21 and 22, encodes isoform 18.
      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:5119
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:271655
      DUF4503; Domain of unknown function (DUF4503)
    22. NM_001352949.1NP_001339878.1  DNA repair-scaffolding protein isoform 19

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:1150
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:302631
      DUF4503; Domain of unknown function (DUF4503)
    23. NM_001352950.1NP_001339879.1  DNA repair-scaffolding protein isoform 20

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:11205
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:357650
      DUF4503; Domain of unknown function (DUF4503)
    24. NM_001352951.1NP_001339880.1  DNA repair-scaffolding protein isoform 21

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:5119
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:271600
      DUF4503; Domain of unknown function (DUF4503)
    25. NM_001352952.1NP_001339881.1  DNA repair-scaffolding protein isoform 22

      Status: VALIDATED

      Description
      Transcript Variant: This variant (27), as well as variants 28, 29, and 30, encodes isoform 22.
      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:158
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:210594
      DUF4503; Domain of unknown function (DUF4503)
    26. NM_001352953.1NP_001339882.1  DNA repair-scaffolding protein isoform 22

      Status: VALIDATED

      Description
      Transcript Variant: This variant (28), as well as variants 27, 29, and 30, encodes isoform 22.
      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:158
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:210594
      DUF4503; Domain of unknown function (DUF4503)
    27. NM_001352955.1NP_001339884.1  DNA repair-scaffolding protein isoform 22

      Status: VALIDATED

      Description
      Transcript Variant: This variant (29), as well as variants 27, 28, and 30, encodes isoform 22.
      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:158
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:210594
      DUF4503; Domain of unknown function (DUF4503)
    28. NM_001352956.1NP_001339885.1  DNA repair-scaffolding protein isoform 22

      Status: VALIDATED

      Description
      Transcript Variant: This variant (30), as well as variants 27, 28, and 29, encodes isoform 22.
      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:158
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:210594
      DUF4503; Domain of unknown function (DUF4503)
    29. NM_001352957.1NP_001339886.1  DNA repair-scaffolding protein isoform 23

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Related
      ENSP00000429193.1, ENST00000519401.5
      Conserved Domains (2) summary
      pfam14950
      Location:158
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:210503
      DUF4503; Domain of unknown function (DUF4503)
    30. NM_001352958.1NP_001339887.1  DNA repair-scaffolding protein isoform 24

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (1) summary
      pfam14951
      Location:105489
      DUF4503; Domain of unknown function (DUF4503)
    31. NM_001352959.1NP_001339888.1  DNA repair-scaffolding protein isoform 25

      Status: VALIDATED

      Source sequence(s)
      AC023991
      Conserved Domains (1) summary
      pfam14951
      Location:26410
      DUF4503; Domain of unknown function (DUF4503)
    32. NM_001352960.1NP_001339889.1  DNA repair-scaffolding protein isoform 26

      Status: VALIDATED

      Source sequence(s)
      AC023991
      Consensus CDS
      CCDS87607.1
      Related
      ENSP00000427889.1, ENST00000517693.5
      Conserved Domains (1) summary
      pfam14951
      Location:1380
      DUF4503; Domain of unknown function (DUF4503)
    33. NM_001352961.1NP_001339890.1  DNA repair-scaffolding protein isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Conserved Domains (2) summary
      pfam14950
      Location:11369
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:521780
      DUF4503; Domain of unknown function (DUF4503)

    RNA

    1. NR_104581.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks several exons compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC233269, BC031627, BM981420
      Related
      ENST00000524126.5
    2. NR_148202.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
    3. NR_148203.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
    4. NR_148204.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269
      Related
      ENST00000522117.5
    5. NR_148205.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC023991, AC024451, AC024649, AC145060, AC233269

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

      Range
      47260878..47736306
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017013281.1XP_016868770.1  DNA repair-scaffolding protein isoform X10

    2. XM_017013280.1XP_016868769.1  DNA repair-scaffolding protein isoform X10

    3. XM_017013273.1XP_016868762.1  DNA repair-scaffolding protein isoform X6

    4. XM_024447116.1XP_024302884.1  DNA repair-scaffolding protein isoform X11

      Conserved Domains (2) summary
      pfam14950
      Location:158
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:210539
      DUF4503; Domain of unknown function (DUF4503)
    5. XM_017013274.2XP_016868763.1  DNA repair-scaffolding protein isoform X7

    6. XM_017013268.2XP_016868757.1  DNA repair-scaffolding protein isoform X1

    7. XM_011517497.3XP_011515799.1  DNA repair-scaffolding protein isoform X4

      Conserved Domains (2) summary
      pfam14950
      Location:11369
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:521870
      DUF4503; Domain of unknown function (DUF4503)
    8. XM_017013269.2XP_016868758.1  DNA repair-scaffolding protein isoform X2

    9. XM_017013270.2XP_016868759.1  DNA repair-scaffolding protein isoform X3

    10. XM_017013279.2XP_016868768.1  DNA repair-scaffolding protein isoform X9

    11. XM_017013271.2XP_016868760.1  DNA repair-scaffolding protein isoform X5

      UniProtKB/Swiss-Prot
      Q14159
      Conserved Domains (2) summary
      pfam14950
      Location:3309
      DUF4502; Domain of unknown function (DUF4502)
      pfam14951
      Location:461790
      DUF4503; Domain of unknown function (DUF4503)
    12. XM_017013289.1XP_016868778.1  DNA repair-scaffolding protein isoform X12

    13. XM_017013276.1XP_016868765.1  DNA repair-scaffolding protein isoform X8

    14. XM_024447117.1XP_024302885.1  DNA repair-scaffolding protein isoform X13

      Conserved Domains (1) summary
      pfam14951
      Location:1380
      DUF4503; Domain of unknown function (DUF4503)

    RNA

    1. XR_001745508.2 RNA Sequence

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