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    ATP13A2 ATPase cation transporting 13A2 [ Homo sapiens (human) ]

    Gene ID: 23400, updated on 17-Jun-2024

    Summary

    Official Symbol
    ATP13A2provided by HGNC
    Official Full Name
    ATPase cation transporting 13A2provided by HGNC
    Primary source
    HGNC:HGNC:30213
    See related
    Ensembl:ENSG00000159363 MIM:610513; AllianceGenome:HGNC:30213
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CLN12; KRPPD; PARK9; SPG78; HSA9947
    Summary
    This gene encodes a member of the P5 subfamily of ATPases which transports inorganic cations as well as other substrates. Mutations in this gene are associated with Kufor-Rakeb syndrome (KRS), also referred to as Parkinson disease 9. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2008]
    Expression
    Ubiquitous expression in brain (RPKM 19.6), spleen (RPKM 11.2) and 24 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ATP13A2 in Genome Data Viewer
    Location:
    1p36.13
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (16985958..17011928, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (16796381..16822349, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (17312453..17338423, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 337 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:17247068-17247840 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:17247841-17248612 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:17248613-17249384 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17249385-17250156 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17250340-17250950 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17252780-17253390 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:17259505-17259699 Neighboring gene ciliary rootlet coiled-coil, rootletin Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 338 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:17298533-17299510 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17300945-17301752 Neighboring gene uncharacterized LOC105376806 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17304877-17305382 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17305891-17306396 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17305383-17305890 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17319735-17320236 Neighboring gene microfibril associated protein 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 274 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 275 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 339 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:17342294-17342828 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:17342829-17343364 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 276 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17356477-17356976 Neighboring gene succinate dehydrogenase complex iron sulfur subunit B Neighboring gene ATAC-STARR-seq lymphoblastoid active region 277 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 278 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17412349-17412850 Neighboring gene peptidyl arginine deiminase 2 Neighboring gene uncharacterized LOC124903861

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.
    EBI GWAS Catalog
    Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
    EBI GWAS Catalog

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ26510

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables ABC-type polyamine transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    enables ATPase-coupled monoatomic cation transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ATPase-coupled monoatomic cation transmembrane transporter activity TAS
    Traceable Author Statement
    more info
     
    enables P-type ion transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables cupric ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables manganese ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables phosphatidic acid binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables phosphatidylinositol-3,5-bisphosphate binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables polyamine transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in autophagosome organization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in autophagosome-lysosome fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in autophagosome-lysosome fusion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in autophagy IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cellular response to manganese ion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cellular response to manganese ion TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in cellular response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cellular response to oxidative stress TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in cellular response to zinc ion TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in extracellular exosome biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in intracellular calcium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular calcium ion homeostasis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in intracellular iron ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in intracellular monoatomic cation homeostasis TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in intracellular zinc ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in lipid homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in lysosomal transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in monoatomic cation transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in monoatomic ion transmembrane transport TAS
    Traceable Author Statement
    more info
     
    involved_in negative regulation of lysosomal protein catabolic process TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in peptidyl-aspartic acid autophosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in polyamine transmembrane transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of exosomal secretion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of exosomal secretion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of protein secretion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein autophosphorylation TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in protein localization to lysosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of autophagosome size IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of autophagosome size IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of autophagy of mitochondrion TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in regulation of chaperone-mediated autophagy TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in regulation of endopeptidase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of intracellular protein transport NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in regulation of lysosomal protein catabolic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in regulation of lysosomal protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of macroautophagy IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of macroautophagy TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in regulation of mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of mitochondrion organization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of mitochondrion organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of neuron apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in regulation of protein localization to nucleus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of ubiquitin-specific protease activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in spermine transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in autophagosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in autophagosome membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in late endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in late endosome membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in lysosomal lumen TAS
    Traceable Author Statement
    more info
     
    located_in lysosomal membrane HDA PubMed 
    located_in lysosomal membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in lysosomal membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in lysosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in multivesicular body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in multivesicular body TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in multivesicular body membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in neuron projection IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in transport vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    polyamine-transporting ATPase 13A2
    Names
    ATPase 13A2
    ATPase type 13A2
    cation-transporting ATPase 13A2
    probable cation-transporting ATPase 13A2
    NP_001135445.1
    NP_001135446.1
    NP_071372.1
    XP_005245867.1
    XP_005245868.1
    XP_005245869.1
    XP_005245872.1
    XP_006710575.1
    XP_006710576.1
    XP_011539430.1
    XP_011539431.1
    XP_016856333.1
    XP_016856334.1
    XP_016856335.1
    XP_016856336.1
    XP_016856337.1
    XP_016856338.1
    XP_016856339.1
    XP_047272493.1
    XP_047272494.1
    XP_047272495.1
    XP_047272498.1
    XP_047272500.1
    XP_047272502.1
    XP_047272503.1
    XP_047272504.1
    XP_047272505.1
    XP_047272506.1
    XP_047272507.1
    XP_047272509.1
    XP_047272510.1
    XP_047272512.1
    XP_047272516.1
    XP_047272518.1
    XP_047272519.1
    XP_047272520.1
    XP_047272521.1
    XP_047272522.1
    XP_047272523.1
    XP_047272524.1
    XP_047272525.1
    XP_047272526.1
    XP_047272527.1
    XP_054188739.1
    XP_054188740.1
    XP_054188741.1
    XP_054188742.1
    XP_054188743.1
    XP_054188744.1
    XP_054188745.1
    XP_054188746.1
    XP_054188747.1
    XP_054188748.1
    XP_054188749.1
    XP_054188750.1
    XP_054188751.1
    XP_054188752.1
    XP_054188753.1
    XP_054188754.1
    XP_054188755.1
    XP_054188756.1
    XP_054188757.1
    XP_054188758.1
    XP_054188759.1
    XP_054188760.1
    XP_054188761.1
    XP_054188762.1
    XP_054188763.1
    XP_054188764.1
    XP_054188765.1
    XP_054188766.1
    XP_054188767.1
    XP_054188768.1
    XP_054188769.1
    XP_054188770.1
    XP_054188771.1
    XP_054188772.1
    XP_054188773.1
    XP_054188774.1
    XP_054188775.1
    XP_054188776.1
    XP_054188777.1
    XP_054188778.1
    XP_054191604.1
    XP_054191605.1
    XP_054191606.1
    XP_054191607.1
    XP_054191608.1
    XP_054191609.1
    XP_054191610.1
    XP_054191611.1
    XP_054191612.1
    XP_054191613.1
    XP_054191614.1
    XP_054191615.1
    XP_054191616.1
    XP_054191617.1
    XP_054191618.1
    XP_054191619.1
    XP_054191620.1
    XP_054191621.1
    XP_054191622.1
    XP_054191623.1
    XP_054191624.1
    XP_054191625.1
    XP_054191626.1
    XP_054191627.1
    XP_054191628.1
    XP_054191629.1
    XP_054191630.1
    XP_054191631.1
    XP_054191632.1
    XP_054191633.1
    XP_054191634.1
    XP_054191635.1
    XP_054191636.1
    XP_054191637.1
    XP_054191638.1
    XP_054191639.1
    XP_054191640.1
    XP_054191641.1
    XP_054191642.1
    XP_054191643.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_009054.1 RefSeqGene

      Range
      5001..30971
      Download
      GenBank, FASTA, Sequence Viewer (Graphics), LRG_834

    mRNA and Protein(s)

    1. NM_001141973.3NP_001135445.1  polyamine-transporting ATPase 13A2 isoform 2

      See identical proteins and their annotated locations for NP_001135445.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform 2). The transcript contains an upstream ORF that could encode a 103aa protein and may modulate translation from the downstream ORF encoding isoform 2.
      Source sequence(s)
      AK290210, AL354615, BC030267, BC034575
      Consensus CDS
      CCDS44073.1
      UniProtKB/TrEMBL
      Q8N4D4
      Related
      ENSP00000413307.1, ENST00000452699.5
      Conserved Domains (1) summary
      TIGR01657
      Location:391112
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
    2. NM_001141974.3NP_001135446.1  polyamine-transporting ATPase 13A2 isoform 3

      See identical proteins and their annotated locations for NP_001135446.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region, and lacks two alternate exons in the 3' coding region which results in a frameshift, compared to variant 1. The resulting protein (isoform 3) is shorter and has a distinct C-terminus, compared to isoform 1. The transcript contains an upstream ORF that could encode a 103aa protein and may modulate translation from the downstream ORF encoding isoform 3.
      Source sequence(s)
      AK075310, BC030267, BC034575, HY024349
      Consensus CDS
      CCDS44072.1
      UniProtKB/TrEMBL
      Q8N4D4
      Related
      ENSP00000341115.5, ENST00000341676.9
      Conserved Domains (5) summary
      COG4087
      Location:806855
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01657
      Location:391034
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:258493
      E1-E2_ATPase; E1-E2 ATPase
      pfam12409
      Location:39169
      P5-ATPase; P5-type ATPase cation transporter
      pfam13246
      Location:623659
      Cation_ATPase; Cation transport ATPase (P-type)
    3. NM_022089.4NP_071372.1  polyamine-transporting ATPase 13A2 isoform 1

      See identical proteins and their annotated locations for NP_071372.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). The transcript contains an upstream ORF that could encode a 103aa protein and may modulate translation from the downstream ORF encoding isoform 1.
      Source sequence(s)
      AL354615, BC030267, HY024349
      Consensus CDS
      CCDS175.1
      UniProtKB/Swiss-Prot
      O75700, Q5JXY1, Q5JXY2, Q6S9Z9, Q9NQ11
      UniProtKB/TrEMBL
      Q8N4D4
      Related
      ENSP00000327214.8, ENST00000326735.13
      Conserved Domains (5) summary
      COG4087
      Location:850899
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01657
      Location:391117
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:263498
      E1-E2_ATPase; E1-E2 ATPase
      pfam12409
      Location:39174
      P5-ATPase; P5-type ATPase cation transporter
      pfam13246
      Location:628664
      Cation_ATPase; Cation transport ATPase (P-type)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      16985958..17011928 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047416542.1XP_047272498.1  polyamine-transporting ATPase 13A2 isoform X10

      UniProtKB/TrEMBL
      Q8N4D4
    2. XM_047416553.1XP_047272509.1  polyamine-transporting ATPase 13A2 isoform X21

      UniProtKB/TrEMBL
      Q8N4D4
    3. XM_047416550.1XP_047272506.1  polyamine-transporting ATPase 13A2 isoform X18

      UniProtKB/TrEMBL
      Q8N4D4
    4. XM_047416569.1XP_047272525.1  polyamine-transporting ATPase 13A2 isoform X38

      UniProtKB/TrEMBL
      Q8N4D4
    5. XM_006710512.2XP_006710575.1  polyamine-transporting ATPase 13A2 isoform X4

      UniProtKB/TrEMBL
      Q8N4D4
      Conserved Domains (5) summary
      COG4087
      Location:844893
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01657
      Location:391072
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:257492
      E1-E2_ATPase; E1-E2 ATPase
      pfam12409
      Location:39168
      P5-ATPase; P5-type ATPase cation transporter
      pfam13246
      Location:622658
      Cation_ATPase; Cation transport ATPase (P-type)
    6. XM_017000845.2XP_016856334.1  polyamine-transporting ATPase 13A2 isoform X13

      UniProtKB/TrEMBL
      Q8N4D4
    7. XM_047416556.1XP_047272512.1  polyamine-transporting ATPase 13A2 isoform X25

      UniProtKB/TrEMBL
      Q8N4D4
    8. XM_047416571.1XP_047272527.1  polyamine-transporting ATPase 13A2 isoform X40

      UniProtKB/TrEMBL
      Q8N4D4
    9. XM_006710513.2XP_006710576.1  polyamine-transporting ATPase 13A2 isoform X9

      UniProtKB/TrEMBL
      Q8N4D4
      Conserved Domains (5) summary
      COG4087
      Location:836885
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01657
      Location:391064
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:249484
      E1-E2_ATPase; E1-E2 ATPase
      pfam12409
      Location:39169
      P5-ATPase; P5-type ATPase cation transporter
      pfam13246
      Location:614650
      Cation_ATPase; Cation transport ATPase (P-type)
    10. XM_017000846.2XP_016856335.1  polyamine-transporting ATPase 13A2 isoform X19

      UniProtKB/TrEMBL
      Q8N4D4
    11. XM_047416538.1XP_047272494.1  polyamine-transporting ATPase 13A2 isoform X7

      UniProtKB/TrEMBL
      Q8N4D4
    12. XM_047416549.1XP_047272505.1  polyamine-transporting ATPase 13A2 isoform X17

      UniProtKB/TrEMBL
      Q8N4D4
    13. XM_047416568.1XP_047272524.1  polyamine-transporting ATPase 13A2 isoform X37

      UniProtKB/TrEMBL
      Q8N4D4
    14. XM_017000849.2XP_016856338.1  polyamine-transporting ATPase 13A2 isoform X28

      UniProtKB/TrEMBL
      Q8N4D4
    15. XM_005245811.2XP_005245868.1  polyamine-transporting ATPase 13A2 isoform X2

      UniProtKB/TrEMBL
      Q8N4D4
      Conserved Domains (5) summary
      COG4087
      Location:845894
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01657
      Location:391073
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:258493
      E1-E2_ATPase; E1-E2 ATPase
      pfam12409
      Location:39169
      P5-ATPase; P5-type ATPase cation transporter
      pfam13246
      Location:623659
      Cation_ATPase; Cation transport ATPase (P-type)
    16. XM_017000847.2XP_016856336.1  polyamine-transporting ATPase 13A2 isoform X22

      UniProtKB/TrEMBL
      Q8N4D4
    17. XM_047416539.1XP_047272495.1  polyamine-transporting ATPase 13A2 isoform X8

      UniProtKB/TrEMBL
      Q8N4D4
    18. XM_047416548.1XP_047272504.1  polyamine-transporting ATPase 13A2 isoform X16

      UniProtKB/TrEMBL
      Q8N4D4
    19. XM_047416563.1XP_047272519.1  polyamine-transporting ATPase 13A2 isoform X30

      UniProtKB/TrEMBL
      Q8N4D4
    20. XM_047416537.1XP_047272493.1  polyamine-transporting ATPase 13A2 isoform X5

      UniProtKB/TrEMBL
      Q8N4D4
    21. XM_047416546.1XP_047272502.1  polyamine-transporting ATPase 13A2 isoform X14

      UniProtKB/TrEMBL
      Q8N4D4
    22. XM_047416564.1XP_047272520.1  polyamine-transporting ATPase 13A2 isoform X32

      UniProtKB/TrEMBL
      Q8N4D4
    23. XM_047416567.1XP_047272523.1  polyamine-transporting ATPase 13A2 isoform X36

      UniProtKB/TrEMBL
      Q8N4D4
    24. XM_047416554.1XP_047272510.1  polyamine-transporting ATPase 13A2 isoform X24

      UniProtKB/TrEMBL
      Q8N4D4
    25. XM_047416560.1XP_047272516.1  polyamine-transporting ATPase 13A2 isoform X27

      UniProtKB/TrEMBL
      Q8N4D4
    26. XM_005245810.2XP_005245867.1  polyamine-transporting ATPase 13A2 isoform X1

      UniProtKB/TrEMBL
      Q8N4D4
      Conserved Domains (5) summary
      COG4087
      Location:849898
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01657
      Location:391077
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:262497
      E1-E2_ATPase; E1-E2 ATPase
      pfam12409
      Location:39114
      P5-ATPase; P5-type ATPase cation transporter
      pfam13246
      Location:627663
      Cation_ATPase; Cation transport ATPase (P-type)
    27. XM_047416544.1XP_047272500.1  polyamine-transporting ATPase 13A2 isoform X11

      UniProtKB/TrEMBL
      Q8N4D4
    28. XM_047416551.1XP_047272507.1  polyamine-transporting ATPase 13A2 isoform X20

      UniProtKB/TrEMBL
      Q8N4D4
    29. XM_047416566.1XP_047272522.1  polyamine-transporting ATPase 13A2 isoform X34

      UniProtKB/TrEMBL
      Q8N4D4
    30. XM_047416570.1XP_047272526.1  polyamine-transporting ATPase 13A2 isoform X39

      UniProtKB/TrEMBL
      Q8N4D4
    31. XM_047416565.1XP_047272521.1  polyamine-transporting ATPase 13A2 isoform X33

      UniProtKB/TrEMBL
      Q8N4D4
    32. XM_005245812.2XP_005245869.1  polyamine-transporting ATPase 13A2 isoform X6

      UniProtKB/TrEMBL
      Q8N4D4
      Conserved Domains (5) summary
      COG4087
      Location:841890
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01657
      Location:391069
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:254489
      E1-E2_ATPase; E1-E2 ATPase
      pfam12409
      Location:39174
      P5-ATPase; P5-type ATPase cation transporter
      pfam13246
      Location:619655
      Cation_ATPase; Cation transport ATPase (P-type)
    33. XM_047416547.1XP_047272503.1  polyamine-transporting ATPase 13A2 isoform X15

      UniProtKB/TrEMBL
      Q8N4D4
    34. XM_047416562.1XP_047272518.1  polyamine-transporting ATPase 13A2 isoform X29

      UniProtKB/TrEMBL
      Q8N4D4
    35. XM_011541128.2XP_011539430.1  polyamine-transporting ATPase 13A2 isoform X3

      UniProtKB/TrEMBL
      Q8N4D4
      Conserved Domains (5) summary
      COG4087
      Location:845894
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01657
      Location:391073
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:263498
      E1-E2_ATPase; E1-E2 ATPase
      pfam12409
      Location:39174
      P5-ATPase; P5-type ATPase cation transporter
      pfam13246
      Location:623659
      Cation_ATPase; Cation transport ATPase (P-type)
    36. XM_017000844.2XP_016856333.1  polyamine-transporting ATPase 13A2 isoform X12

      UniProtKB/TrEMBL
      Q8N4D4
    37. XM_011541129.2XP_011539431.1  polyamine-transporting ATPase 13A2 isoform X31

      UniProtKB/TrEMBL
      Q8N4D4
      Conserved Domains (5) summary
      COG4087
      Location:781830
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01657
      Location:391009
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:263498
      E1-E2_ATPase; E1-E2 ATPase
      pfam12409
      Location:39174
      P5-ATPase; P5-type ATPase cation transporter
      pfam13246
      Location:559595
      Cation_ATPase; Cation transport ATPase (P-type)
    38. XM_017000850.2XP_016856339.1  polyamine-transporting ATPase 13A2 isoform X35

      UniProtKB/TrEMBL
      Q8N4D4
    39. XM_005245815.2XP_005245872.1  polyamine-transporting ATPase 13A2 isoform X23

      UniProtKB/TrEMBL
      Q8N4D4
      Conserved Domains (5) summary
      COG4087
      Location:811860
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01657
      Location:391039
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:263498
      E1-E2_ATPase; E1-E2 ATPase
      pfam12409
      Location:39174
      P5-ATPase; P5-type ATPase cation transporter
      pfam13246
      Location:628664
      Cation_ATPase; Cation transport ATPase (P-type)
    40. XM_017000848.2XP_016856337.1  polyamine-transporting ATPase 13A2 isoform X26

      UniProtKB/TrEMBL
      Q8N4D4

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_025791756.1 Reference GRCh38.p14 PATCHES

      Range
      1401135..1427111 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054332773.1XP_054188748.1  polyamine-transporting ATPase 13A2 isoform X10

      UniProtKB/TrEMBL
      Q8N4D4
    2. XM_054332784.1XP_054188759.1  polyamine-transporting ATPase 13A2 isoform X21

      UniProtKB/TrEMBL
      Q8N4D4
    3. XM_054332781.1XP_054188756.1  polyamine-transporting ATPase 13A2 isoform X18

      UniProtKB/TrEMBL
      Q8N4D4
    4. XM_054332801.1XP_054188776.1  polyamine-transporting ATPase 13A2 isoform X38

      UniProtKB/TrEMBL
      Q8N4D4
    5. XM_054332767.1XP_054188742.1  polyamine-transporting ATPase 13A2 isoform X4

      UniProtKB/TrEMBL
      Q8N4D4
    6. XM_054332776.1XP_054188751.1  polyamine-transporting ATPase 13A2 isoform X13

      UniProtKB/TrEMBL
      Q8N4D4
    7. XM_054332788.1XP_054188763.1  polyamine-transporting ATPase 13A2 isoform X25

      UniProtKB/TrEMBL
      Q8N4D4
    8. XM_054332803.1XP_054188778.1  polyamine-transporting ATPase 13A2 isoform X40

      UniProtKB/TrEMBL
      Q8N4D4
    9. XM_054332772.1XP_054188747.1  polyamine-transporting ATPase 13A2 isoform X9

      UniProtKB/TrEMBL
      Q8N4D4
    10. XM_054332782.1XP_054188757.1  polyamine-transporting ATPase 13A2 isoform X19

      UniProtKB/TrEMBL
      Q8N4D4
    11. XM_054332770.1XP_054188745.1  polyamine-transporting ATPase 13A2 isoform X7

      UniProtKB/TrEMBL
      Q8N4D4
    12. XM_054332780.1XP_054188755.1  polyamine-transporting ATPase 13A2 isoform X17

      UniProtKB/TrEMBL
      Q8N4D4
    13. XM_054332800.1XP_054188775.1  polyamine-transporting ATPase 13A2 isoform X37

      UniProtKB/TrEMBL
      Q8N4D4
    14. XM_054332791.1XP_054188766.1  polyamine-transporting ATPase 13A2 isoform X28

      UniProtKB/TrEMBL
      Q8N4D4
    15. XM_054332765.1XP_054188740.1  polyamine-transporting ATPase 13A2 isoform X2

      UniProtKB/TrEMBL
      Q8N4D4
    16. XM_054332785.1XP_054188760.1  polyamine-transporting ATPase 13A2 isoform X22

      UniProtKB/TrEMBL
      Q8N4D4
    17. XM_054332771.1XP_054188746.1  polyamine-transporting ATPase 13A2 isoform X8

      UniProtKB/TrEMBL
      Q8N4D4
    18. XM_054332779.1XP_054188754.1  polyamine-transporting ATPase 13A2 isoform X16

      UniProtKB/TrEMBL
      Q8N4D4
    19. XM_054332793.1XP_054188768.1  polyamine-transporting ATPase 13A2 isoform X30

      UniProtKB/TrEMBL
      Q8N4D4
    20. XM_054332768.1XP_054188743.1  polyamine-transporting ATPase 13A2 isoform X5

      UniProtKB/TrEMBL
      Q8N4D4
    21. XM_054332777.1XP_054188752.1  polyamine-transporting ATPase 13A2 isoform X14

      UniProtKB/TrEMBL
      Q8N4D4
    22. XM_054332795.1XP_054188770.1  polyamine-transporting ATPase 13A2 isoform X32

      UniProtKB/TrEMBL
      Q8N4D4
    23. XM_054332799.1XP_054188774.1  polyamine-transporting ATPase 13A2 isoform X36

      UniProtKB/TrEMBL
      Q8N4D4
    24. XM_054332787.1XP_054188762.1  polyamine-transporting ATPase 13A2 isoform X24

      UniProtKB/TrEMBL
      Q8N4D4
    25. XM_054332790.1XP_054188765.1  polyamine-transporting ATPase 13A2 isoform X27

      UniProtKB/TrEMBL
      Q8N4D4
    26. XM_054332764.1XP_054188739.1  polyamine-transporting ATPase 13A2 isoform X1

      UniProtKB/TrEMBL
      Q8N4D4
    27. XM_054332774.1XP_054188749.1  polyamine-transporting ATPase 13A2 isoform X11

      UniProtKB/TrEMBL
      Q8N4D4
    28. XM_054332783.1XP_054188758.1  polyamine-transporting ATPase 13A2 isoform X20

      UniProtKB/TrEMBL
      Q8N4D4
    29. XM_054332797.1XP_054188772.1  polyamine-transporting ATPase 13A2 isoform X34

      UniProtKB/TrEMBL
      Q8N4D4
    30. XM_054332802.1XP_054188777.1  polyamine-transporting ATPase 13A2 isoform X39

      UniProtKB/TrEMBL
      Q8N4D4
    31. XM_054332796.1XP_054188771.1  polyamine-transporting ATPase 13A2 isoform X33

      UniProtKB/TrEMBL
      Q8N4D4
    32. XM_054332769.1XP_054188744.1  polyamine-transporting ATPase 13A2 isoform X6

      UniProtKB/TrEMBL
      Q8N4D4
    33. XM_054332778.1XP_054188753.1  polyamine-transporting ATPase 13A2 isoform X15

      UniProtKB/TrEMBL
      Q8N4D4
    34. XM_054332792.1XP_054188767.1  polyamine-transporting ATPase 13A2 isoform X29

      UniProtKB/TrEMBL
      Q8N4D4
    35. XM_054332766.1XP_054188741.1  polyamine-transporting ATPase 13A2 isoform X3

      UniProtKB/TrEMBL
      Q8N4D4
    36. XM_054332775.1XP_054188750.1  polyamine-transporting ATPase 13A2 isoform X12

      UniProtKB/TrEMBL
      Q8N4D4
    37. XM_054332794.1XP_054188769.1  polyamine-transporting ATPase 13A2 isoform X31

      UniProtKB/TrEMBL
      Q8N4D4
    38. XM_054332798.1XP_054188773.1  polyamine-transporting ATPase 13A2 isoform X35

      UniProtKB/TrEMBL
      Q8N4D4
    39. XM_054332786.1XP_054188761.1  polyamine-transporting ATPase 13A2 isoform X23

      UniProtKB/TrEMBL
      Q8N4D4
    40. XM_054332789.1XP_054188764.1  polyamine-transporting ATPase 13A2 isoform X26

      UniProtKB/TrEMBL
      Q8N4D4

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      16796381..16822349 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054335638.1XP_054191613.1  polyamine-transporting ATPase 13A2 isoform X10

      UniProtKB/TrEMBL
      Q8N4D4
    2. XM_054335649.1XP_054191624.1  polyamine-transporting ATPase 13A2 isoform X21

      UniProtKB/TrEMBL
      Q8N4D4
    3. XM_054335646.1XP_054191621.1  polyamine-transporting ATPase 13A2 isoform X18

      UniProtKB/TrEMBL
      Q8N4D4
    4. XM_054335666.1XP_054191641.1  polyamine-transporting ATPase 13A2 isoform X38

      UniProtKB/TrEMBL
      Q8N4D4
    5. XM_054335632.1XP_054191607.1  polyamine-transporting ATPase 13A2 isoform X4

      UniProtKB/TrEMBL
      Q8N4D4
    6. XM_054335641.1XP_054191616.1  polyamine-transporting ATPase 13A2 isoform X13

      UniProtKB/TrEMBL
      Q8N4D4
    7. XM_054335653.1XP_054191628.1  polyamine-transporting ATPase 13A2 isoform X25

      UniProtKB/TrEMBL
      Q8N4D4
    8. XM_054335668.1XP_054191643.1  polyamine-transporting ATPase 13A2 isoform X40

      UniProtKB/TrEMBL
      Q8N4D4
    9. XM_054335637.1XP_054191612.1  polyamine-transporting ATPase 13A2 isoform X9

      UniProtKB/TrEMBL
      Q8N4D4
    10. XM_054335647.1XP_054191622.1  polyamine-transporting ATPase 13A2 isoform X19

      UniProtKB/TrEMBL
      Q8N4D4
    11. XM_054335635.1XP_054191610.1  polyamine-transporting ATPase 13A2 isoform X7

      UniProtKB/TrEMBL
      Q8N4D4
    12. XM_054335645.1XP_054191620.1  polyamine-transporting ATPase 13A2 isoform X17

      UniProtKB/TrEMBL
      Q8N4D4
    13. XM_054335665.1XP_054191640.1  polyamine-transporting ATPase 13A2 isoform X37

      UniProtKB/TrEMBL
      Q8N4D4
    14. XM_054335656.1XP_054191631.1  polyamine-transporting ATPase 13A2 isoform X28

      UniProtKB/TrEMBL
      Q8N4D4
    15. XM_054335630.1XP_054191605.1  polyamine-transporting ATPase 13A2 isoform X2

      UniProtKB/TrEMBL
      Q8N4D4
    16. XM_054335650.1XP_054191625.1  polyamine-transporting ATPase 13A2 isoform X22

      UniProtKB/TrEMBL
      Q8N4D4
    17. XM_054335636.1XP_054191611.1  polyamine-transporting ATPase 13A2 isoform X8

      UniProtKB/TrEMBL
      Q8N4D4
    18. XM_054335644.1XP_054191619.1  polyamine-transporting ATPase 13A2 isoform X16

      UniProtKB/TrEMBL
      Q8N4D4
    19. XM_054335658.1XP_054191633.1  polyamine-transporting ATPase 13A2 isoform X30

      UniProtKB/TrEMBL
      Q8N4D4
    20. XM_054335633.1XP_054191608.1  polyamine-transporting ATPase 13A2 isoform X5

      UniProtKB/TrEMBL
      Q8N4D4
    21. XM_054335642.1XP_054191617.1  polyamine-transporting ATPase 13A2 isoform X14

      UniProtKB/TrEMBL
      Q8N4D4
    22. XM_054335660.1XP_054191635.1  polyamine-transporting ATPase 13A2 isoform X32

      UniProtKB/TrEMBL
      Q8N4D4
    23. XM_054335664.1XP_054191639.1  polyamine-transporting ATPase 13A2 isoform X36

      UniProtKB/TrEMBL
      Q8N4D4
    24. XM_054335652.1XP_054191627.1  polyamine-transporting ATPase 13A2 isoform X24

      UniProtKB/TrEMBL
      Q8N4D4
    25. XM_054335655.1XP_054191630.1  polyamine-transporting ATPase 13A2 isoform X27

      UniProtKB/TrEMBL
      Q8N4D4
    26. XM_054335629.1XP_054191604.1  polyamine-transporting ATPase 13A2 isoform X1

      UniProtKB/TrEMBL
      Q8N4D4
    27. XM_054335639.1XP_054191614.1  polyamine-transporting ATPase 13A2 isoform X11

      UniProtKB/TrEMBL
      Q8N4D4
    28. XM_054335648.1XP_054191623.1  polyamine-transporting ATPase 13A2 isoform X20

      UniProtKB/TrEMBL
      Q8N4D4
    29. XM_054335662.1XP_054191637.1  polyamine-transporting ATPase 13A2 isoform X34

      UniProtKB/TrEMBL
      Q8N4D4
    30. XM_054335667.1XP_054191642.1  polyamine-transporting ATPase 13A2 isoform X39

      UniProtKB/TrEMBL
      Q8N4D4
    31. XM_054335661.1XP_054191636.1  polyamine-transporting ATPase 13A2 isoform X33

      UniProtKB/TrEMBL
      Q8N4D4
    32. XM_054335634.1XP_054191609.1  polyamine-transporting ATPase 13A2 isoform X6

      UniProtKB/TrEMBL
      Q8N4D4
    33. XM_054335643.1XP_054191618.1  polyamine-transporting ATPase 13A2 isoform X15

      UniProtKB/TrEMBL
      Q8N4D4
    34. XM_054335657.1XP_054191632.1  polyamine-transporting ATPase 13A2 isoform X29

      UniProtKB/TrEMBL
      Q8N4D4
    35. XM_054335631.1XP_054191606.1  polyamine-transporting ATPase 13A2 isoform X3

      UniProtKB/TrEMBL
      Q8N4D4
    36. XM_054335640.1XP_054191615.1  polyamine-transporting ATPase 13A2 isoform X12

      UniProtKB/TrEMBL
      Q8N4D4
    37. XM_054335659.1XP_054191634.1  polyamine-transporting ATPase 13A2 isoform X31

      UniProtKB/TrEMBL
      Q8N4D4
    38. XM_054335663.1XP_054191638.1  polyamine-transporting ATPase 13A2 isoform X35

      UniProtKB/TrEMBL
      Q8N4D4
    39. XM_054335651.1XP_054191626.1  polyamine-transporting ATPase 13A2 isoform X23

      UniProtKB/TrEMBL
      Q8N4D4
    40. XM_054335654.1XP_054191629.1  polyamine-transporting ATPase 13A2 isoform X26

      UniProtKB/TrEMBL
      Q8N4D4