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    Pim3 proviral integration site 3 [ Mus musculus (house mouse) ]

    Gene ID: 223775, updated on 8-Jun-2019

    Summary

    Official Symbol
    Pim3provided by MGI
    Official Full Name
    proviral integration site 3provided by MGI
    Primary source
    MGI:MGI:1355297
    See related
    Ensembl:ENSMUSG00000035828
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Kid1; BC026639
    Expression
    Broad expression in adrenal adult (RPKM 73.4), duodenum adult (RPKM 37.2) and 26 other tissues See more
    Orthologs

    Genomic context

    See Pim3 in Genome Data Viewer
    Location:
    15; 15 E3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (88862194..88865726)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (88692624..88696156)

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase) Neighboring gene cysteine-rich with EGF-like domains 2 Neighboring gene predicted gene, 33049 Neighboring gene predicted gene, 38643 Neighboring gene tubulin tyrosine ligase-like family, member 8 Neighboring gene megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human) Neighboring gene proteasome maturation protein pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    • PluriNetWork, organism-specific biosystem (from WikiPathways)
      PluriNetWork, organism-specific biosystemThe aim of the PluriNetWork is to give an overview of specific mechanisms associated with pluripotency in mouse. Each node represents a gene and its corresponding protein product. As stated, we inten...

    General gene information

    Markers

    Homology

    Clone Names

    • MGC27707, MGC37517

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    histone phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of insulin secretion involved in cellular response to glucose stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    protein autophosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein autophosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    serine/threonine-protein kinase pim-3
    Names
    KID-1/kinase induced by depolarization
    NP_663453.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145478.2NP_663453.1  serine/threonine-protein kinase pim-3

      See identical proteins and their annotated locations for NP_663453.1

      Status: PROVISIONAL

      Source sequence(s)
      AC117700
      Consensus CDS
      CCDS27734.1
      UniProtKB/Swiss-Prot
      P58750
      UniProtKB/TrEMBL
      Q3TX64
      Related
      ENSMUSP00000044603.9, ENSMUST00000042818.10
      Conserved Domains (1) summary
      cl21453
      Location:39293
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

      Range
      88862194..88865726
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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