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    PPP1R32 protein phosphatase 1 regulatory subunit 32 [ Homo sapiens (human) ]

    Gene ID: 220004, updated on 12-Oct-2019

    Summary

    Official Symbol
    PPP1R32provided by HGNC
    Official Full Name
    protein phosphatase 1 regulatory subunit 32provided by HGNC
    Primary source
    HGNC:HGNC:28869
    See related
    Ensembl:ENSG00000162148
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    IIIG9; C11orf66
    Expression
    Biased expression in testis (RPKM 29.1) and lung (RPKM 2.8) See more
    Orthologs

    Genomic context

    See PPP1R32 in Genome Data Viewer
    Location:
    11q12.2
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109.20190905 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (61481120..61490928)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (61248585..61258400)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene cleavage and polyadenylation specific factor 7 Neighboring gene succinate dehydrogenase complex assembly factor 2 Neighboring gene RNA, 7SL, cytoplasmic 23, pseudogene Neighboring gene uncharacterized LOC105369329 Neighboring gene microRNA 4488

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Potential readthrough

    Included gene: SDHAF2

    Homology

    Clone Names

    • FLJ32771

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    phosphatase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    phosphatase binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    protein phosphatase 1 regulatory subunit 32

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001170753.2NP_001164224.1  protein phosphatase 1 regulatory subunit 32 isoform 2

      See identical proteins and their annotated locations for NP_001164224.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      BC043246, BC053995
      Consensus CDS
      CCDS53641.1
      UniProtKB/Swiss-Prot
      Q7Z5V6
      Related
      ENSP00000391560.2, ENST00000432063.6
      Conserved Domains (1) summary
      pfam15691
      Location:2396
      PPP1R32; Protein phosphatase 1 regulatory subunit 32
    2. NM_145017.3NP_659454.2  protein phosphatase 1 regulatory subunit 32 isoform 1

      See identical proteins and their annotated locations for NP_659454.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      BC053995, BI561157
      Consensus CDS
      CCDS8008.1
      UniProtKB/Swiss-Prot
      Q7Z5V6
      UniProtKB/TrEMBL
      G3F4G3
      Related
      ENSP00000344140.2, ENST00000338608.7
      Conserved Domains (1) summary
      pfam15691
      Location:2416
      PPP1R32; Protein phosphatase 1 regulatory subunit 32

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

      Range
      61481120..61490928
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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