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    ELN elastin [ Homo sapiens (human) ]

    Gene ID: 2006, updated on 17-Sep-2024

    Summary

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    Official Symbol
    ELNprovided by HGNC
    Official Full Name
    elastinprovided by HGNC
    Primary source
    HGNC:HGNC:3327
    See related
    Ensembl:ENSG00000049540 MIM:130160; AllianceGenome:HGNC:3327
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    WS; WBS; SVAS; ADCL1
    Summary
    This gene encodes a protein that is one of the two components of elastic fibers. Elastic fibers comprise part of the extracellular matrix and confer elasticity to organs and tissues including the heart, skin, lungs, ligaments, and blood vessels. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Degradation products of the encoded protein, known as elastin-derived peptides or elastokines, bind the elastin receptor complex and other receptors and stimulate migration and proliferation of monocytes and skin fibroblasts. Elastokines can also contribute to cancer progression. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa. [provided by RefSeq, Aug 2017]
    Expression
    Broad expression in urinary bladder (RPKM 40.8), gall bladder (RPKM 38.1) and 24 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    Location:
    7q11.23
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (74028173..74069907)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (75231309..75273042)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (73442503..73484237)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26130 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18268 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26131 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18269 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73270039-73270538 Neighboring gene methyltransferase like 27 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73284301-73285230 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73285703-73286258 Neighboring gene transmembrane protein 270 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73313687-73314360 Neighboring gene Sharpr-MPRA regulatory region 8209 Neighboring gene Sharpr-MPRA regulatory region 9451 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73414582-73415082 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr7:73417073-73418272 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26134 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73440914-73441886 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73442859-73443830 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73447495-73448122 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73448123-73448750 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73465984-73466807 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73475944-73476444 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73476445-73476945 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73497513-73498191 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73496834-73497512 Neighboring gene ELN antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18271 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18272 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26136 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73499459-73500058 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73500059-73500656 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73504464-73504964 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73504965-73505465 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73507121-73507662 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26138 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73508745-73509285 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26139 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73519804-73520304 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73529551-73530186 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73530187-73530821 Neighboring gene LIM domain kinase 1 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73547393-73548180 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73553155-73553684 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:73576750-73576945 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73588725-73589238 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73589239-73589751 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73593778-73594278 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73594279-73594779 Neighboring gene eukaryotic translation initiation factor 4H Neighboring gene microRNA 590

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Mechanical Properties and Functions of Elastin: An Overview. Trębacz H, et al. Biomolecules, 2023 Mar 22. PMID 36979509, Free PMC Article
    2. Autosomal dominant cutis laxa and critical stenosis of the left main coronary artery in a 21-year-old female with an intronic mutation in the elastin gene. Krarup NT, et al. Am J Med Genet A, 2023 Apr. PMID 36541930
    3. ELN-Related Cutis Laxa. Adam MP, et al. , 1993. PMID 36173875
    4. Degeneration of the lumbar spine and its relation to the expression of collagen and elastin in facet joint capsules and ligament flavum. Voelker A, et al. Acta Orthop Traumatol Turc, 2022 May. PMID 35703510, Free PMC Article
    5. Research on the expression of elastin in the conjoint fascial sheath for the correction of severe unilateral congenital blepharoptosis. Liu Z, et al. BMC Ophthalmol, 2022 Jun 8. PMID 35676638, Free PMC Article

    See all (298) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Impact of Cyclic Strain on Elastin Synthesis in a 3D Human Myometrial Culture Model.
      Title: Impact of Cyclic Strain on Elastin Synthesis in a 3D Human Myometrial Culture Model.
    2. Lysyl oxidase-mediated elastin upregulation promotes the proliferation and migration of human retinal endothelial cells.
      Title: Lysyl oxidase-mediated elastin upregulation promotes the proliferation and migration of human retinal endothelial cells.
    3. A non-canonical role of ELN protects from cellular senescence by limiting iron-dependent regulation of gene expression.
      Title: A non-canonical role of ELN protects from cellular senescence by limiting iron-dependent regulation of gene expression.
    4. Fetal Diagnosis of Supravalvular Aortic Stenosis and Pulmonary Stenosis in a Family with Non-Syndromic Elastin Mutation.
      Title: Fetal Diagnosis of Supravalvular Aortic Stenosis and Pulmonary Stenosis in a Family with Non-Syndromic Elastin Mutation.
    5. TGF-alpha/EGFR signaling promotes lipopolysaccharide-induced abnormal elastin deposition and alveolar simplification.
      Title: TGF-α/EGFR signaling promotes lipopolysaccharide-induced abnormal elastin deposition and alveolar simplification.
    6. Elastin recoil is driven by the hydrophobic effect.
      Title: Elastin recoil is driven by the hydrophobic effect.
    7. Single Nucleotide Polymorphisms Mutation of Tropoelastin Gene Affects Tropoelastin mRNA and Elastin Expressions in Human Aortic Smooth Muscle Cells.
      Title: Single Nucleotide Polymorphisms Mutation of Tropoelastin Gene Affects Tropoelastin mRNA and Elastin Expressions in Human Aortic Smooth Muscle Cells.
    8. Configuration of elastin fibers in the intra- and extra-capsule ligaments of the elderly cricoarytenoid joint.
      Title: Configuration of elastin fibers in the intra- and extra-capsule ligaments of the elderly cricoarytenoid joint.
    9. Elastin stabilization prevents impaired biomechanics in human pulmonary arteries and pulmonary hypertension in rats with left heart disease.
      Title: Elastin stabilization prevents impaired biomechanics in human pulmonary arteries and pulmonary hypertension in rats with left heart disease.
    10. Assessment of fibrillin-2 and elastin gene polymorphisms in patients with a traumatic Achilles tendon rupture: Is Achilles tendon rupture a genetic disease?
      Title: Assessment of fibrillin-2 and elastin gene polymorphisms in patients with a traumatic Achilles tendon rupture: Is Achilles tendon rupture a genetic disease?
    Submit: New GeneRIF Correction See all GeneRIFs (218)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Cutis laxa, autosomal dominant 1
    MedGen: C3276539 OMIM: 123700 GeneReviews: FBLN5-Related Cutis Laxa, ELN-Related Cutis Laxa
    		Compare labs
    Supravalvar aortic stenosis
    MedGen: C0003499 OMIM: 185500 GeneReviews: Not available
    		Compare labs
    Williams syndrome
    MedGen: C0175702 OMIM: 194050 GeneReviews: Williams Syndrome
    		Compare labs

    Copy number response

    Description
    Copy number response
    Triplosensitivity

    No evidence available (Last evaluated 2012-07-10)

    ClinGen Genome Curation Page
    Haploinsufficency

    Sufficient evidence for dosage pathogenicity (Last evaluated 2012-07-10)

    ClinGen Genome Curation Page

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ38671, FLJ43523

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables extracellular matrix binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables extracellular matrix constituent conferring elasticity RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    enables extracellular matrix structural constituent ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables extracellular matrix structural constituent RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in animal organ morphogenesis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in aortic valve morphogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in blood circulation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in extracellular matrix assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in outflow tract morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of smooth muscle cell proliferation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in respiratory gaseous exchange by respiratory system TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in skeletal muscle tissue development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in stress fiber assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix HDA PubMed 
    located_in elastic fiber IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular matrix TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in extracellular region TAS
    Traceable Author Statement
    more info
    		  

    General protein information

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    Preferred Names
    elastin
    Names
    tropoelastin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_009261.1 RefSeqGene

      Range
      5077..46811
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_000501.4 → NP_000492.2  elastin isoform a precursor

      See identical proteins and their annotated locations for NP_000492.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes isoform (a).
      Source sequence(s)
      AA600350, AC005056, BC035570
      Consensus CDS
      CCDS5562.2
      UniProtKB/TrEMBL
      B4E3S4
      Related
      ENSP00000252034.7, ENST00000252034.12

    2. NM_001081752.3 → NP_001075221.1  elastin isoform b precursor

      See identical proteins and their annotated locations for NP_001075221.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks alternate in-frame exons, compared to variant 1, resulting in a shorter protein (isoform b), compared to isoform a.
      Source sequence(s)
      AA600350, AC005056, BX538199
      Consensus CDS
      CCDS43599.1
      UniProtKB/TrEMBL
      B4E3S4
      Related
      ENSP00000369949.4, ENST00000380575.8

    3. NM_001081753.3 → NP_001075222.1  elastin isoform c precursor

      See identical proteins and their annotated locations for NP_001075222.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks alternate in-frame exons, compared to variant 1, resulting in a shorter protein (isoform c), compared to isoform a.
      Source sequence(s)
      AA600350, AC005056, AK095990
      Consensus CDS
      CCDS47611.1
      UniProtKB/TrEMBL
      B4E3S4
      Related
      ENSP00000391129.1, ENST00000429192.5

    4. NM_001081754.3 → NP_001075223.1  elastin isoform d precursor

      See identical proteins and their annotated locations for NP_001075223.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform d), compared to isoform a.
      Source sequence(s)
      AA600350, AC005056, BX537939
      Consensus CDS
      CCDS43598.1
      UniProtKB/TrEMBL
      B4E3S4
      Related
      ENSP00000349540.5, ENST00000357036.9

    5. NM_001081755.3 → NP_001075224.1  elastin isoform e precursor

      See identical proteins and their annotated locations for NP_001075224.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) lacks alternate in-frame exons and uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform e), compared to isoform a.
      Source sequence(s)
      AA600350, AC005056, AK225659
      Consensus CDS
      CCDS47612.1
      UniProtKB/TrEMBL
      B4E3S4
      Related
      ENSP00000369950.5, ENST00000380576.9

    6. NM_001278912.2 → NP_001265841.1  elastin isoform f precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) lacks an alternate in-frame exon in the 3' coding region compared to variant 1. It encodes isoform f which is shorter compared to isoform a.
      Source sequence(s)
      AA600350, AC005056, AK304845
      Consensus CDS
      CCDS64674.1
      UniProtKB/TrEMBL
      B4E3S4, E7ENM0
      Related
      ENSP00000389857.1, ENST00000445912.5

    7. NM_001278913.2 → NP_001265842.1  elastin isoform g precursor

      See identical proteins and their annotated locations for NP_001265842.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) has multiple differences in the coding region but maintains the reading frame compared to variant 1. It encodes isoform g which is shorter compared to isoform a.
      Source sequence(s)
      AA600350, AC005056, AK075554
      Consensus CDS
      CCDS64676.1
      UniProtKB/TrEMBL
      G5E950, Q8NBI4
      Related
      ENSP00000315607.7, ENST00000320492.11

    8. NM_001278914.2 → NP_001265843.1  elastin isoform h precursor

      See identical proteins and their annotated locations for NP_001265843.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) lacks two in-frame exons in the coding region compared to variant 1. It encodes isoform h which is shorter compared to isoform a.
      Source sequence(s)
      AA600350, AC005056, AK125511
      Consensus CDS
      CCDS64677.1
      UniProtKB/TrEMBL
      B4E3S4, G3V0G6
      Related
      ENSP00000392575.1, ENST00000414324.5

    9. NM_001278915.2 → NP_001265844.1  elastin isoform i precursor

      See identical proteins and their annotated locations for NP_001265844.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) uses an alternate in-frame splice site in the central coding region compared to variant 1. It encodes isoform i which is longer compared to isoform a.
      Source sequence(s)
      AA600350, AC005056, M36860
      Consensus CDS
      CCDS64673.1
      UniProtKB/TrEMBL
      B4E3S4
      Related
      ENSP00000369936.4, ENST00000380562.8

    10. NM_001278916.2 → NP_001265845.1  elastin isoform j precursor

      See identical proteins and their annotated locations for NP_001265845.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) has multiple differences in the coding region but maintains the reading frame compared to variant 1. It encodes isoform j which is shorter compared to isoform a.
      Source sequence(s)
      AC005056, BC065566
      Consensus CDS
      CCDS64675.1
      UniProtKB/TrEMBL
      B4E3S4
      Related
      ENSP00000369958.4, ENST00000380584.8

    11. NM_001278917.2 → NP_001265846.1  elastin isoform k precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11) lacks an in-frame exon in the 3' coding region compared to variant 1. It encodes isoform k which is shorter compared to isoform a.
      Source sequence(s)
      AA600350, AB208942
      Consensus CDS
      CCDS64678.1
      UniProtKB/TrEMBL
      B4E3S4, E7EN65
      Related
      ENSP00000403162.1, ENST00000458204.5

    12. NM_001278918.2 → NP_001265847.1  elastin isoform l precursor

      See identical proteins and their annotated locations for NP_001265847.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12) has multiple differences in the coding region but maintains the reading frame compared to variant 1. It encodes isoform l which is shorter compared to isoform a.
      Source sequence(s)
      AA600350, AC005056, AK092232
      Consensus CDS
      CCDS75617.1
      UniProtKB/TrEMBL
      B3KRT8, Q8NBI4
      Related
      ENSP00000480955.1, ENST00000621115.4

    13. NM_001278939.2 → NP_001265868.1  elastin isoform m precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13) has multiple difference in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (m) is longer than isoform a. This variant lacks full-length support. The structure is based on PMID: 9215671.
      Source sequence(s)
      AC005056
      Consensus CDS
      CCDS75616.1
      UniProtKB/Swiss-Prot
      B3KTS6, O15336, O15337, P15502, Q14233, Q14234, Q14235, Q14238, Q6P0L4, Q6ZWJ6, Q75MU5, Q7Z316, Q7Z3F5, Q9UMF5
      UniProtKB/TrEMBL
      A7L3I8
      Related
      ENSP00000510104.1, ENST00000692049.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      74028173..74069907
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011515868.3 → XP_011514170.1  elastin isoform X1

      UniProtKB/TrEMBL
      B4E3S4

    2. XM_011515876.3 → XP_011514178.1  elastin isoform X21

      UniProtKB/TrEMBL
      B4E3S4

    3. XM_011515873.3 → XP_011514175.1  elastin isoform X7

      UniProtKB/TrEMBL
      B4E3S4

    4. XM_011515872.3 → XP_011514174.1  elastin isoform X6

      UniProtKB/TrEMBL
      B4E3S4

    5. XM_047419965.1 → XP_047275921.1  elastin isoform X25

      UniProtKB/TrEMBL
      B4E3S4

    6. XM_011515877.3 → XP_011514179.1  elastin isoform X27

      UniProtKB/TrEMBL
      B4E3S4

    7. XM_011515871.3 → XP_011514173.1  elastin isoform X4

      UniProtKB/TrEMBL
      B4E3S4

    8. XM_047419959.1 → XP_047275915.1  elastin isoform X17

      UniProtKB/TrEMBL
      B4E3S4

    9. XM_017011814.3 → XP_016867303.1  elastin isoform X20

      UniProtKB/TrEMBL
      Q8NBI4

    10. XM_047419981.1 → XP_047275937.1  elastin isoform X42

      UniProtKB/TrEMBL
      B4E3S4

    11. XM_047419968.1 → XP_047275924.1  elastin isoform X29

      UniProtKB/TrEMBL
      B4E3S4

    12. XM_047419971.1 → XP_047275927.1  elastin isoform X32

      UniProtKB/TrEMBL
      B4E3S4
      Related
      ENSP00000369926.4, ENST00000380553.8

    13. XM_047419954.1 → XP_047275910.1  elastin isoform X10

      UniProtKB/TrEMBL
      B4E3S4

    14. XM_047419970.1 → XP_047275926.1  elastin isoform X31

      UniProtKB/TrEMBL
      B4E3S4

    15. XM_047419972.1 → XP_047275928.1  elastin isoform X33

      UniProtKB/TrEMBL
      B4E3S4

    16. XM_005250188.2 → XP_005250245.1  elastin isoform X8

      UniProtKB/TrEMBL
      B4E3S4

    17. XM_047419966.1 → XP_047275922.1  elastin isoform X26

      UniProtKB/TrEMBL
      B4E3S4

    18. XM_047419969.1 → XP_047275925.1  elastin isoform X30

      UniProtKB/TrEMBL
      Q8NBI4

    19. XM_047419967.1 → XP_047275923.1  elastin isoform X28

      UniProtKB/TrEMBL
      B4E3S4

    20. XM_011515870.2 → XP_011514172.1  elastin isoform X3

      UniProtKB/TrEMBL
      B4E3S4

    21. XM_047419956.1 → XP_047275912.1  elastin isoform X14

      UniProtKB/TrEMBL
      B4E3S4

    22. XM_047419957.1 → XP_047275913.1  elastin isoform X15

      UniProtKB/TrEMBL
      B4E3S4

    23. XM_005250187.3 → XP_005250244.1  elastin isoform X5

      UniProtKB/TrEMBL
      B4E3S4

    24. XM_047419963.1 → XP_047275919.1  elastin isoform X23

      UniProtKB/TrEMBL
      B4E3S4

    25. XM_047419978.1 → XP_047275934.1  elastin isoform X39

      UniProtKB/TrEMBL
      B4E3S4

    26. XM_047419964.1 → XP_047275920.1  elastin isoform X24

      UniProtKB/TrEMBL
      B4E3S4

    27. XM_047419958.1 → XP_047275914.1  elastin isoform X16

      UniProtKB/TrEMBL
      B4E3S4

    28. XM_047419979.1 → XP_047275935.1  elastin isoform X40

      UniProtKB/TrEMBL
      Q8NBI4

    29. XM_011515869.2 → XP_011514171.1  elastin isoform X2

      UniProtKB/TrEMBL
      B4E3S4

    30. XM_047419955.1 → XP_047275911.1  elastin isoform X12

      UniProtKB/TrEMBL
      B4E3S4

    31. XM_047419973.1 → XP_047275929.1  elastin isoform X34

      UniProtKB/TrEMBL
      Q8NBI4

    32. XM_047419960.1 → XP_047275916.1  elastin isoform X18

      UniProtKB/TrEMBL
      B4E3S4

    33. XM_047419976.1 → XP_047275932.1  elastin isoform X37

      UniProtKB/TrEMBL
      B4E3S4

    34. XM_047419962.1 → XP_047275918.1  elastin isoform X22

      UniProtKB/TrEMBL
      B4E3S4

    35. XM_047419961.1 → XP_047275917.1  elastin isoform X19

      UniProtKB/TrEMBL
      B4E3S4

    36. XM_047419980.1 → XP_047275936.1  elastin isoform X41

      UniProtKB/TrEMBL
      B4E3S4

    37. XM_017011813.1 → XP_016867302.1  elastin isoform X13

      UniProtKB/TrEMBL
      B4E3S4

    38. XM_047419977.1 → XP_047275933.1  elastin isoform X38

      UniProtKB/TrEMBL
      Q8NBI4

    39. XM_011515874.2 → XP_011514176.1  elastin isoform X9

      UniProtKB/TrEMBL
      B4E3S4

    40. XM_011515875.3 → XP_011514177.1  elastin isoform X11

      UniProtKB/TrEMBL
      B4E3S4

    41. XM_047419974.1 → XP_047275930.1  elastin isoform X35

      UniProtKB/TrEMBL
      B4E3S4

    42. XM_047419975.1 → XP_047275931.1  elastin isoform X36

      UniProtKB/TrEMBL
      B4E3S4

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      75231309..75273042
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054357419.1 → XP_054213394.1  elastin isoform X1

      UniProtKB/TrEMBL
      B4E3S4

    2. XM_054357439.1 → XP_054213414.1  elastin isoform X21

      UniProtKB/TrEMBL
      B4E3S4

    3. XM_054357425.1 → XP_054213400.1  elastin isoform X7

      UniProtKB/TrEMBL
      B4E3S4

    4. XM_054357424.1 → XP_054213399.1  elastin isoform X6

      UniProtKB/TrEMBL
      B4E3S4

    5. XM_054357443.1 → XP_054213418.1  elastin isoform X25

      UniProtKB/TrEMBL
      B4E3S4

    6. XM_054357445.1 → XP_054213420.1  elastin isoform X27

      UniProtKB/TrEMBL
      B4E3S4

    7. XM_054357422.1 → XP_054213397.1  elastin isoform X4

      UniProtKB/TrEMBL
      B4E3S4

    8. XM_054357435.1 → XP_054213410.1  elastin isoform X17

      UniProtKB/TrEMBL
      B4E3S4

    9. XM_054357438.1 → XP_054213413.1  elastin isoform X20

      UniProtKB/TrEMBL
      Q8NBI4

    10. XM_054357460.1 → XP_054213435.1  elastin isoform X42

      UniProtKB/TrEMBL
      B4E3S4

    11. XM_054357447.1 → XP_054213422.1  elastin isoform X29

      UniProtKB/TrEMBL
      B4E3S4

    12. XM_054357450.1 → XP_054213425.1  elastin isoform X32

      UniProtKB/TrEMBL
      B4E3S4

    13. XM_054357428.1 → XP_054213403.1  elastin isoform X10

      UniProtKB/TrEMBL
      B4E3S4

    14. XM_054357449.1 → XP_054213424.1  elastin isoform X31

      UniProtKB/TrEMBL
      B4E3S4

    15. XM_054357451.1 → XP_054213426.1  elastin isoform X33

      UniProtKB/TrEMBL
      B4E3S4

    16. XM_054357426.1 → XP_054213401.1  elastin isoform X8

      UniProtKB/TrEMBL
      B4E3S4

    17. XM_054357444.1 → XP_054213419.1  elastin isoform X26

      UniProtKB/TrEMBL
      B4E3S4

    18. XM_054357448.1 → XP_054213423.1  elastin isoform X30

      UniProtKB/TrEMBL
      Q8NBI4

    19. XM_054357446.1 → XP_054213421.1  elastin isoform X28

      UniProtKB/TrEMBL
      B4E3S4

    20. XM_054357421.1 → XP_054213396.1  elastin isoform X3

      UniProtKB/TrEMBL
      B4E3S4

    21. XM_054357432.1 → XP_054213407.1  elastin isoform X14

      UniProtKB/TrEMBL
      B4E3S4

    22. XM_054357433.1 → XP_054213408.1  elastin isoform X15

      UniProtKB/TrEMBL
      B4E3S4

    23. XM_054357423.1 → XP_054213398.1  elastin isoform X5

      UniProtKB/TrEMBL
      B4E3S4

    24. XM_054357441.1 → XP_054213416.1  elastin isoform X23

      UniProtKB/TrEMBL
      B4E3S4

    25. XM_054357457.1 → XP_054213432.1  elastin isoform X39

      UniProtKB/TrEMBL
      B4E3S4

    26. XM_054357442.1 → XP_054213417.1  elastin isoform X24

      UniProtKB/TrEMBL
      B4E3S4

    27. XM_054357434.1 → XP_054213409.1  elastin isoform X16

      UniProtKB/TrEMBL
      B4E3S4

    28. XM_054357458.1 → XP_054213433.1  elastin isoform X40

      UniProtKB/TrEMBL
      Q8NBI4

    29. XM_054357420.1 → XP_054213395.1  elastin isoform X2

      UniProtKB/TrEMBL
      B4E3S4

    30. XM_054357430.1 → XP_054213405.1  elastin isoform X12

      UniProtKB/TrEMBL
      B4E3S4

    31. XM_054357452.1 → XP_054213427.1  elastin isoform X34

      UniProtKB/TrEMBL
      Q8NBI4

    32. XM_054357436.1 → XP_054213411.1  elastin isoform X18

      UniProtKB/TrEMBL
      B4E3S4

    33. XM_054357455.1 → XP_054213430.1  elastin isoform X37

      UniProtKB/TrEMBL
      B4E3S4

    34. XM_054357440.1 → XP_054213415.1  elastin isoform X22

      UniProtKB/TrEMBL
      B4E3S4

    35. XM_054357437.1 → XP_054213412.1  elastin isoform X19

      UniProtKB/TrEMBL
      B4E3S4

    36. XM_054357459.1 → XP_054213434.1  elastin isoform X41

      UniProtKB/TrEMBL
      B4E3S4

    37. XM_054357431.1 → XP_054213406.1  elastin isoform X13

      UniProtKB/TrEMBL
      B4E3S4

    38. XM_054357456.1 → XP_054213431.1  elastin isoform X38

      UniProtKB/TrEMBL
      Q8NBI4

    39. XM_054357427.1 → XP_054213402.1  elastin isoform X9

      UniProtKB/TrEMBL
      B4E3S4

    40. XM_054357429.1 → XP_054213404.1  elastin isoform X11

      UniProtKB/TrEMBL
      B4E3S4

    41. XM_054357453.1 → XP_054213428.1  elastin isoform X35

      UniProtKB/TrEMBL
      B4E3S4

    42. XM_054357454.1 → XP_054213429.1  elastin isoform X36

      UniProtKB/TrEMBL
      B4E3S4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P15502.4 GenPept UniProtKB/Swiss-Prot:P15502

    Gene LinkOut

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