Format

Send to:

Choose Destination
    • Showing Current items.

    FOXD4L1 forkhead box D4 like 1 [ Homo sapiens (human) ]

    Gene ID: 200350, updated on 15-Jun-2019

    Summary

    Official Symbol
    FOXD4L1provided by HGNC
    Official Full Name
    forkhead box D4 like 1provided by HGNC
    Primary source
    HGNC:HGNC:18521
    See related
    Ensembl:ENSG00000184492 MIM:611084
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FOXD5; bA395L14.1
    Summary
    This gene is a member of the forkhead/winged-helix (FOX) family of transcription factors with highly conserved FOX DNA-binding domains. Members of the FOX family of transcription factors are regulators of embryogenesis and may play a role in human cancer. This gene lies in a region of chromosome 2 that surrounds the site where two ancestral chromosomes fused to form human chromosome 2. This region is duplicated elsewhere in the human genome, primarily in subtelomeric and pericentromeric locations, thus mutiple copies of this gene have been found. [provided by RefSeq, Jul 2008]
    Orthologs

    Genomic context

    See FOXD4L1 in Genome Data Viewer
    Location:
    2q14.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 2 NC_000002.12 (113499084..113501150)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (114256661..114258727)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101927400 Neighboring gene uncharacterized LOC107985936 Neighboring gene COBW domain containing 2 Neighboring gene uncharacterized LOC112268422 Neighboring gene long intergenic non-protein coding RNA 1961 Neighboring gene PGM5P4 antisense RNA 1 Neighboring gene phosphoglucomutase 5 pseudogene 4

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    anatomical structure morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    forkhead box protein D4-like 1
    Names
    FOXD4-like 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012184.4NP_036316.1  forkhead box protein D4-like 1

      See identical proteins and their annotated locations for NP_036316.1

      Status: REVIEWED

      Source sequence(s)
      AK122950, AK125398, AY344639
      Consensus CDS
      CCDS2117.1
      UniProtKB/Swiss-Prot
      Q9NU39
      UniProtKB/TrEMBL
      B3KVK3
      Related
      ENSP00000302756.5, ENST00000306507.6
      Conserved Domains (1) summary
      pfam00250
      Location:107193
      Forkhead; Forkhead domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

      Range
      113499084..113501150
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center