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    NBPF11 NBPF member 11 [ Homo sapiens (human) ]

    Gene ID: 200030, updated on 17-Jun-2019

    Summary

    Official Symbol
    NBPF11provided by HGNC
    Official Full Name
    NBPF member 11provided by HGNC
    Primary source
    HGNC:HGNC:31993
    See related
    Ensembl:ENSG00000263956 MIM:614001
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NBPF24
    Expression
    Ubiquitous expression in skin (RPKM 15.7), ovary (RPKM 14.5) and 25 other tissues See more
    Orthologs

    Genomic context

    See NBPF11 in Genome Data Viewer
    Location:
    1q21.2
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    109.20190607 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (148102046..148152281, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (146032542..146082633, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene tRNA-Asn (anticodon GTT) 9-2 Neighboring gene phosphodiesterase 4D interacting protein pseudogene 1 Neighboring gene profilin 1 pseudogene 4 Neighboring gene abhydrolase domain containing 17A pseudogene 1 Neighboring gene uncharacterized LOC105371227 Neighboring gene long intergenic non-protein coding RNA 2805

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ61663, DKFZp451B1418

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    neuroblastoma breakpoint family member 11
    Names
    neuroblastoma breakpoint family, member 24

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101663.4NP_001095133.3  neuroblastoma breakpoint family member 11 isoform b

      See identical proteins and their annotated locations for NP_001095133.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) differs in the 5' UTR and coding sequence and initiates translation at an alternate downstream start codon compared to variant 3. The resulting isoform (b) is shorter at the N-terminus compared to isoform 3.
      Source sequence(s)
      AC239803, AI865471, AK302413, BX648497
      Consensus CDS
      CCDS41381.2
      UniProtKB/Swiss-Prot
      Q86T75
      Related
      ENSP00000484213.1, ENST00000614015.4
      Conserved Domains (1) summary
      pfam06758
      Location:686748
      DUF1220; Repeat of unknown function (DUF1220)
    2. NM_183372.6NP_899228.4  neuroblastoma breakpoint family member 11 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) encodes the longer isoform (a).
      Source sequence(s)
      AC239803, AI865471, BC136292
      UniProtKB/Swiss-Prot
      Q86T75
      Conserved Domains (1) summary
      pfam06758
      Location:740802
      DUF1220; Repeat of unknown function (DUF1220)

    RNA

    1. NR_046188.4 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate donor splice site at an internal exon compared to variant 1. It is represented as non-coding because the use of the translational start codon, as used in variant 1, renders this transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC239803, AI865471, AL832622, BC136292
    2. NR_110864.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses two alternate splice junctions and lacks two alternate exons compared to variant 3. It is represented as non-coding because the use of the translational start codon, as used in variant 3, renders this transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC239803, AI865471, BC136292, BX648497
      Related
      ENST00000614506.4

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      148102046..148152281 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024453858.1XP_024309626.1  neuroblastoma breakpoint family member 11 isoform X1

      Conserved Domains (2) summary
      pfam06758
      Location:736801
      DUF1220; Repeat of unknown function (DUF1220)
      cl25732
      Location:65455
      SMC_N; RecF/RecN/SMC N terminal domain
    2. XM_024453859.1XP_024309627.1  neuroblastoma breakpoint family member 11 isoform X2

      Conserved Domains (2) summary
      pfam06758
      Location:505565
      DUF1220; Repeat of unknown function (DUF1220)
      cl26511
      Location:107527
      Neuromodulin_N; Gap junction protein N-terminal region

    RNA

    1. XR_002959669.1 RNA Sequence

    2. XR_002959662.1 RNA Sequence

    3. XR_002959670.1 RNA Sequence

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