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    Rgs16 regulator of G-protein signaling 16 [ Mus musculus (house mouse) ]

    Gene ID: 19734, updated on 18-Sep-2018

    Summary

    Official Symbol
    Rgs16provided by MGI
    Official Full Name
    regulator of G-protein signaling 16provided by MGI
    Primary source
    MGI:MGI:108407
    See related
    Ensembl:ENSMUSG00000026475 Vega:OTTMUSG00000020889
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rgsr; Rgs14
    Expression
    Broad expression in liver E18 (RPKM 12.8), CNS E11.5 (RPKM 10.4) and 15 other tissues See more
    Orthologs

    Genomic context

    See Rgs16 in Genome Data Viewer
    Location:
    1 G3; 1 65.43 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (153740353..153745468)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (155587483..155592598)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene regulator of G-protein signaling 8 Neighboring gene RIKEN cDNA C230024C17 gene Neighboring gene ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) Neighboring gene regulator of G-protein signaling like 1 Neighboring gene predicted gene, 41974

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    • Calcium Regulation in the Cardiac Cell, organism-specific biosystem (from WikiPathways)
      Calcium Regulation in the Cardiac Cell, organism-specific biosystemCalcium is a common signaling mechanism, as once it enters the cytoplasm it exerts allosteric regulatory affects on many enzymes and proteins. Calcium can act in signal transduction after influx resu...
    • EGFR1 Signaling Pathway, organism-specific biosystem (from WikiPathways)
      EGFR1 Signaling Pathway, organism-specific biosystemThe androgen receptor is a member of the nuclear receptor family of ligand activated transcription factors. These receptors bind to steroid hormones, thyroid hormone, retinoids and vitamin D among ot...
    • Myometrial Relaxation and Contraction Pathways, organism-specific biosystem (from WikiPathways)
      Myometrial Relaxation and Contraction Pathways, organism-specific biosystemThis pathway illustrates signaling networks implicated in uterine muscle contraction at labor and quiescence throughout gestation (pregnancy). The muscle of the uterus, responsible for contractile ac...

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTPase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    GTPase activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    GTPase activator activity TAS
    Traceable Author Statement
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    G protein-coupled receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    G protein-coupled receptor signaling pathway TAS
    Traceable Author Statement
    more info
    PubMed 
    negative regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of GTPase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm TAS
    Traceable Author Statement
    more info
    PubMed 
    intrinsic component of membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane raft ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    regulator of G-protein signaling 16
    Names
    A28-RGS14P
    RGS-R
    retinal-specific RGS
    retinally abundant regulator of G-protein signaling

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011267.3NP_035397.2  regulator of G-protein signaling 16

      See identical proteins and their annotated locations for NP_035397.2

      Status: VALIDATED

      Source sequence(s)
      AI854148, AK079543
      Consensus CDS
      CCDS15376.1
      UniProtKB/Swiss-Prot
      P97428
      UniProtKB/TrEMBL
      Q542U0
      Related
      ENSMUSP00000027748.7, OTTMUSP00000022875, ENSMUST00000027748.7, OTTMUST00000049392
      Conserved Domains (1) summary
      cd08710
      Location:65178
      RGS_RGS16; Regulator of G protein signaling (RGS) domain found in the RGS16 protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      153740353..153745468
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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