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    Ptprc protein tyrosine phosphatase receptor type C [ Mus musculus (house mouse) ]

    Gene ID: 19264, updated on 1-Oct-2024

    Summary

    Official Symbol
    Ptprcprovided by MGI
    Official Full Name
    protein tyrosine phosphatase receptor type Cprovided by MGI
    Primary source
    MGI:MGI:97810
    See related
    Ensembl:ENSMUSG00000026395 AllianceGenome:MGI:97810
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    loc; B220; Cd45; L-CA; Ly-5; T200; CD45R; Lyt-4
    Summary
    Enables several functions, including heparan sulfate proteoglycan binding activity; heparin binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation; positive regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within several processes, including lymphocyte differentiation; positive regulation of lymphocyte activation; and regulation of protein phosphorylation. Located in external side of plasma membrane; focal adhesion; and membrane raft. Is expressed in several structures, including 3rd branchial arch; alimentary system; cardiovascular system; hemolymphoid system; and placenta. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatitis C; multiple sclerosis; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in spleen adult (RPKM 50.1), thymus adult (RPKM 49.7) and 5 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ptprc in Genome Data Viewer
    Location:
    1 E4; 1 60.73 cM
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (137990601..138103491, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (138062859..138175756, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41959 Neighboring gene microRNA 181b-1 Neighboring gene predicted gene, 34353 Neighboring gene STARR-positive B cell enhancer mm9_chr1:139941089-139941390 Neighboring gene STARR-seq mESC enhancer starr_02458 Neighboring gene STARR-seq mESC enhancer starr_02459 Neighboring gene STARR-positive B cell enhancer ABC_E7753 Neighboring gene STARR-positive B cell enhancer ABC_E11693 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:140033032-140033324 Neighboring gene STARR-positive B cell enhancer ABC_E3306 Neighboring gene RIKEN cDNA A130071D04 gene Neighboring gene STARR-positive B cell enhancer ABC_E5810 Neighboring gene STARR-positive B cell enhancer ABC_E11090 Neighboring gene STARR-seq mESC enhancer starr_02460 Neighboring gene STARR-seq mESC enhancer starr_02461 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:140088258-140088597 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:140088625-140088861 Neighboring gene terminal nucleotidyltransferase 2, pseudogene 2 Neighboring gene STARR-positive B cell enhancer ABC_E2563 Neighboring gene predicted gene, 53479

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ankyrin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ankyrin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables heparan sulfate proteoglycan binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables heparin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein kinase binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables protein tyrosine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein tyrosine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein tyrosine phosphatase activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    enables protein tyrosine phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein tyrosine phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables signaling receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables spectrin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables spectrin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmembrane receptor protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within B cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in B cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of B cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in B cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within B cell receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in B cell receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of MAPK cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in T cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within T cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in T cell receptor signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in T cell receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in T cell receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of alpha-beta T cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in bone marrow development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in bone marrow development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell cycle phase transition IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell cycle phase transition ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within defense response to virus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in defense response to virus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in dephosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of extrinsic apoptotic signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of gamma-delta T cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in hematopoietic progenitor cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in hematopoietic progenitor cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within heterotypic cell-cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within leukocyte cell-cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in natural killer cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of ERK1 and ERK2 cascade IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of T cell mediated cytotoxicity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of cell adhesion involved in substrate-bound cell migration IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of cell adhesion involved in substrate-bound cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of cytokine-mediated signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of interleukin-2 production IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of interleukin-4-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within negative regulation of peptidyl-tyrosine phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of protein autophosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of protein kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of protein kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within negative thymic T cell selection IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of peptidyl-tyrosine phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of B cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of B cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of ERK1 and ERK2 cascade IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of Fc receptor mediated stimulatory signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of MAP kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of MAPK cascade IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of MAPK cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of T cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of T cell mediated cytotoxicity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of T cell mediated immunity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of T cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of alpha-beta T cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of antigen receptor-mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of calcium-mediated signaling IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of extrinsic apoptotic signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of gamma-delta T cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of hematopoietic stem cell migration IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of hematopoietic stem cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of humoral immune response mediated by circulating immunoglobulin IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of immunoglobulin production ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of interleukin-2 production IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of isotype switching to IgG isotypes IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of peptidyl-tyrosine phosphorylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of phagocytosis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of stem cell proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of stem cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of tumor necrosis factor production IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within positive thymic T cell selection IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of protein autophosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein dephosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of T cell receptor signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in regulation of cell cycle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within regulation of extrinsic apoptotic signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of gene expression IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of humoral immune response mediated by circulating immunoglobulin IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of interleukin-8 production IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of interleukin-8 production ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of phagocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of protein tyrosine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of receptor signaling pathway via JAK-STAT ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in release of sequestered calcium ion into cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in response to gamma radiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in stem cell development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in stem cell development ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in bleb IEA
    Inferred from Electronic Annotation
    more info
     
    located_in bleb ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell periphery IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic side of plasma membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in external side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in focal adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane microdomain IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane raft IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane raft IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    receptor-type tyrosine-protein phosphatase C
    Names
    leukocyte common antigen
    lymphocyte antigen 5
    lymphocyte common antigen
    NP_001104786.2
    NP_001255215.1
    NP_001407709.1
    NP_001407710.1
    NP_035340.3
    XP_006529321.1
    XP_006529322.1
    XP_006529323.1
    XP_006529324.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001111316.3NP_001104786.2  receptor-type tyrosine-protein phosphatase C isoform 1 precursor

      See identical proteins and their annotated locations for NP_001104786.2

      Status: VALIDATED

      Source sequence(s)
      AC122903, AC159278
      Consensus CDS
      CCDS48383.2
      UniProtKB/Swiss-Prot
      E9QLT5, P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1, S4R1S4, S4R2V1
      UniProtKB/TrEMBL
      Q64730
      Related
      ENSMUSP00000138350.2, ENSMUST00000183301.8
      Conserved Domains (6) summary
      cd00063
      Location:474553
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam05109
      Location:27191
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd14557
      Location:696896
      R-PTPc-C-1; catalytic domain of receptor-type tyrosine-protein phosphatase C, repeat 1
      cd14558
      Location:10061211
      R-PTP-C-2; PTP-like domain of receptor-type tyrosine-protein phosphatase C, repeat 2
      pfam12453
      Location:731
      PTP_N; Protein tyrosine phosphatase N terminal
      pfam12567
      Location:212265
      CD45; Leukocyte receptor CD45
    2. NM_001268286.2NP_001255215.1  receptor-type tyrosine-protein phosphatase C isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AC122903, AC159278
      Consensus CDS
      CCDS59542.1
      UniProtKB/TrEMBL
      Q3U382, S4R1M0
      Related
      ENSMUSP00000138275.2, ENSMUST00000182755.8
      Conserved Domains (5) summary
      smart00194
      Location:478737
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:506737
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:311390
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12453
      Location:731
      PTP_N; Protein tyrosine phosphatase N terminal
      pfam12567
      Location:49102
      CD45; Leukocyte receptor CD45
    3. NM_001420780.1NP_001407709.1  receptor-type tyrosine-protein phosphatase C isoform 5 precursor

      Status: VALIDATED

      Source sequence(s)
      AC122903, AC159278
      UniProtKB/TrEMBL
      Q3U382
    4. NM_001420781.1NP_001407710.1  receptor-type tyrosine-protein phosphatase C isoform 4 precursor

      Status: VALIDATED

      Source sequence(s)
      AC122903, AC159278
      UniProtKB/TrEMBL
      Q3U382
    5. NM_011210.5NP_035340.3  receptor-type tyrosine-protein phosphatase C isoform 2 precursor

      See identical proteins and their annotated locations for NP_035340.3

      Status: VALIDATED

      Source sequence(s)
      AC122903, AC159278
      Consensus CDS
      CCDS15330.2
      UniProtKB/TrEMBL
      Q3U382
      Related
      ENSMUSP00000138800.2, ENSMUST00000182283.8
      Conserved Domains (5) summary
      smart00194
      Location:502761
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cd00047
      Location:530761
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:335414
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12453
      Location:731
      PTP_N; Protein tyrosine phosphatase N terminal
      pfam12567
      Location:73126
      CD45; Leukocyte receptor CD45

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      137990601..138103491 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006529258.4XP_006529321.1  receptor-type tyrosine-protein phosphatase C isoform X1

      See identical proteins and their annotated locations for XP_006529321.1

      UniProtKB/Swiss-Prot
      E9QLT5, P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1, S4R1S4, S4R2V1
      UniProtKB/TrEMBL
      Q64730
      Conserved Domains (6) summary
      cd00063
      Location:474553
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam05109
      Location:27191
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd14557
      Location:696896
      R-PTPc-C-1; catalytic domain of receptor-type tyrosine-protein phosphatase C, repeat 1
      cd14558
      Location:10061211
      R-PTP-C-2; PTP-like domain of receptor-type tyrosine-protein phosphatase C, repeat 2
      pfam12453
      Location:731
      PTP_N; Protein tyrosine phosphatase N terminal
      pfam12567
      Location:212265
      CD45; Leukocyte receptor CD45
    2. XM_006529259.4XP_006529322.1  receptor-type tyrosine-protein phosphatase C isoform X1

      See identical proteins and their annotated locations for XP_006529322.1

      UniProtKB/Swiss-Prot
      E9QLT5, P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1, S4R1S4, S4R2V1
      UniProtKB/TrEMBL
      Q64730
      Conserved Domains (6) summary
      cd00063
      Location:474553
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam05109
      Location:27191
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd14557
      Location:696896
      R-PTPc-C-1; catalytic domain of receptor-type tyrosine-protein phosphatase C, repeat 1
      cd14558
      Location:10061211
      R-PTP-C-2; PTP-like domain of receptor-type tyrosine-protein phosphatase C, repeat 2
      pfam12453
      Location:731
      PTP_N; Protein tyrosine phosphatase N terminal
      pfam12567
      Location:212265
      CD45; Leukocyte receptor CD45
    3. XM_006529260.1XP_006529323.1  receptor-type tyrosine-protein phosphatase C isoform X2

      UniProtKB/TrEMBL
      Q64730
      Conserved Domains (6) summary
      PHA03255
      Location:18150
      PHA03255; BDLF3; Provisional
      cd00063
      Location:431510
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14557
      Location:653853
      R-PTPc-C-1; catalytic domain of receptor-type tyrosine-protein phosphatase C, repeat 1
      cd14558
      Location:9631168
      R-PTP-C-2; PTP-like domain of receptor-type tyrosine-protein phosphatase C, repeat 2
      pfam12453
      Location:731
      PTP_N; Protein tyrosine phosphatase N terminal
      pfam12567
      Location:169222
      CD45; Leukocyte receptor CD45
    4. XM_006529261.5XP_006529324.1  receptor-type tyrosine-protein phosphatase C isoform X3

      UniProtKB/TrEMBL
      Q64730
      Conserved Domains (6) summary
      cd00063
      Location:427506
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam05109
      Location:13143
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd14557
      Location:649849
      R-PTPc-C-1; catalytic domain of receptor-type tyrosine-protein phosphatase C, repeat 1
      cd14558
      Location:9591164
      R-PTP-C-2; PTP-like domain of receptor-type tyrosine-protein phosphatase C, repeat 2
      pfam12453
      Location:731
      PTP_N; Protein tyrosine phosphatase N terminal
      pfam12567
      Location:165218
      CD45; Leukocyte receptor CD45