Format

Send to:

Choose Destination
    • Showing Current items.

    Pax7 paired box 7 [ Mus musculus (house mouse) ]

    Gene ID: 18509, updated on 10-Oct-2019

    Summary

    Official Symbol
    Pax7provided by MGI
    Official Full Name
    paired box 7provided by MGI
    Primary source
    MGI:MGI:97491
    See related
    Ensembl:ENSMUSG00000028736
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pax-7
    Expression
    Biased expression in whole brain E14.5 (RPKM 2.5), CNS E11.5 (RPKM 2.3) and 4 other tissues See more
    Orthologs

    Genomic context

    See Pax7 in Genome Data Viewer
    Location:
    4 D3; 4 70.83 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    108 current GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (139737059..139833530, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (139293996..139388883, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene taste receptor, type 1, member 2 Neighboring gene predicted gene, 42334 Neighboring gene predicted gene, 46873 Neighboring gene uncharacterized LOC102636380 Neighboring gene RIKEN cDNA 4933427I22 gene Neighboring gene kelch domain containing 7A Neighboring gene microRNA 2139

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    DNA-binding transcription factor activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    animal organ morphogenesis TAS
    Traceable Author Statement
    more info
    PubMed 
    cartilage development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    chromatin remodeling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dorsal/ventral neural tube patterning IDA
    Inferred from Direct Assay
    more info
    PubMed 
    embryonic skeletal system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    muscle organ development IEA
    Inferred from Electronic Annotation
    more info
     
    muscle tissue morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    neuron fate commitment IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of histone methylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of histone methylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of myoblast proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of DNA binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of cell fate commitment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated TAS
    Traceable Author Statement
    more info
    PubMed 
    skeletal muscle satellite cell commitment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    skeletal muscle tissue development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    skeletal muscle tissue regeneration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spinal cord association neuron differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription factor complex TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    paired box protein Pax-7
    Names
    paired box gene 7
    paired box transcription factor PAX7

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011039.2NP_035169.1  paired box protein Pax-7

      See identical proteins and their annotated locations for NP_035169.1

      Status: VALIDATED

      Source sequence(s)
      AL831790, AL844480
      Consensus CDS
      CCDS18850.1
      UniProtKB/Swiss-Prot
      P47239
      Related
      ENSMUSP00000030508.6, ENSMUST00000030508.13
      Conserved Domains (3) summary
      smart00351
      Location:34159
      PAX; Paired Box domain
      pfam12360
      Location:345383
      Pax7; Paired box protein 7
      pfam00046
      Location:218271
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p6 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p6 C57BL/6J

      Range
      139737059..139833530 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006538630.2XP_006538693.1  paired box protein Pax-7 isoform X2

      Conserved Domains (3) summary
      smart00351
      Location:34160
      PAX; Paired Box domain
      pfam00046
      Location:219272
      Homeobox; Homeobox domain
      pfam12360
      Location:346384
      Pax7; Paired box protein 7
    2. XM_006538629.2XP_006538692.1  paired box protein Pax-7 isoform X1

      UniProtKB/TrEMBL
      G3UX36
      Related
      ENSMUSP00000133536.1, ENSMUST00000174681.1
      Conserved Domains (3) summary
      smart00351
      Location:34161
      PAX; Paired Box domain
      pfam12360
      Location:347385
      Pax7; Paired box protein 7
      pfam00046
      Location:220273
      Homeobox; Homeobox domain
    3. XM_006538631.2XP_006538694.1  paired box protein Pax-7 isoform X3

      Conserved Domains (3) summary
      smart00351
      Location:34158
      PAX; Paired Box domain
      pfam00046
      Location:217270
      Homeobox; Homeobox domain
      pfam12360
      Location:344382
      Pax7; Paired box protein 7
    Support Center