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    FAM9A family with sequence similarity 9 member A [ Homo sapiens (human) ]

    Gene ID: 171482, updated on 5-Aug-2022

    Summary

    Official Symbol
    FAM9Aprovided by HGNC
    Official Full Name
    family with sequence similarity 9 member Aprovided by HGNC
    Primary source
    HGNC:HGNC:18403
    See related
    Ensembl:ENSG00000183304 MIM:300477; AllianceGenome:HGNC:18403
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TEX39A
    Summary
    This gene is a member of a gene family which arose through duplication on the X chromosome. The encoded protein may be a nuclear protein that is localized to the nucleolus, and has some similarity to a synaptonemal complex protein. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2011]
    Expression
    Restricted expression toward testis (RPKM 1.9) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See FAM9A in Genome Data Viewer
    Location:
    Xp22.31
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (8790795..8801383, complement)
    110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (8357896..8368484, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (8758836..8769424, complement)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene anosmin 1 Neighboring gene dorsal inhibitory axon guidance protein pseudogene 1 Neighboring gene ANAPC15 pseudogene 1 Neighboring gene uncharacterized LOC105373125

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC138227, MGC142009

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in spermatid development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in synaptonemal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    protein FAM9A
    Names
    testis expressed 39A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_016564.2 RefSeqGene

      Range
      5001..15589
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001171186.1NP_001164657.1  protein FAM9A

      See identical proteins and their annotated locations for NP_001164657.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript (1). Both variant 1 and 2 encode the same protein.
      Source sequence(s)
      AC003685, BC143805
      Consensus CDS
      CCDS14131.1
      UniProtKB/Swiss-Prot
      Q2M2D1, Q8IZU1
      Related
      ENSP00000440163.1, ENST00000543214.1
      Conserved Domains (1) summary
      pfam04803
      Location:277332
      Cor1; Cor1/Xlr/Xmr conserved region
    2. NM_174951.3NP_777611.1  protein FAM9A

      See identical proteins and their annotated locations for NP_777611.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC003685, AF494343
      Consensus CDS
      CCDS14131.1
      UniProtKB/Swiss-Prot
      Q2M2D1, Q8IZU1
      Related
      ENSP00000370391.3, ENST00000381003.7
      Conserved Domains (1) summary
      pfam04803
      Location:277332
      Cor1; Cor1/Xlr/Xmr conserved region

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      8790795..8801383 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      8357896..8368484 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)