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    PYDC2 pyrin domain containing 2 [ Homo sapiens (human) ]

    Gene ID: 152138, updated on 15-Jun-2019

    Summary

    Official Symbol
    PYDC2provided by HGNC
    Official Full Name
    pyrin domain containing 2provided by HGNC
    Primary source
    HGNC:HGNC:33512
    See related
    Ensembl:ENSG00000253548 MIM:615701
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    POP2; cPOP2
    Orthologs

    Genomic context

    See PYDC2 in Genome Data Viewer
    Location:
    3q28
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 3 NC_000003.12 (191461163..191461456)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (191178952..191179245)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene OSTN antisense RNA 1 Neighboring gene osteocrin Neighboring gene urotensin 2B Neighboring gene coiled-coil domain containing 50 Neighboring gene uncharacterized LincR-0002 Neighboring gene uncharacterized LOC105374275 Neighboring gene uncharacterized LOC105374276

    Genomic regions, transcripts, and products

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • NOD-like receptor signaling pathway, organism-specific biosystem (from KEGG)
      NOD-like receptor signaling pathway, organism-specific biosystemSpecific families of pattern recognition receptors are responsible for detecting various pathogens and generating innate immune responses. The intracellular NOD-like receptor (NLR) family contains mo...
    • NOD-like receptor signaling pathway, conserved biosystem (from KEGG)
      NOD-like receptor signaling pathway, conserved biosystemSpecific families of pattern recognition receptors are responsible for detecting various pathogens and generating innate immune responses. The intracellular NOD-like receptor (NLR) family contains mo...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    pyrin domain-containing protein 2
    Names
    cellular POP2
    pyrin-only protein 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083308.1NP_001076777.1  pyrin domain-containing protein 2

      See identical proteins and their annotated locations for NP_001076777.1

      Status: VALIDATED

      Source sequence(s)
      AY858112
      UniProtKB/Swiss-Prot
      Q56P42
      Related
      ENSP00000492367.1, ENST00000518817.1
      Conserved Domains (1) summary
      cd08320
      Location:1194
      Pyrin_NALPs; Pyrin death domain found in NALP proteins

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

      Range
      191461163..191461456
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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