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    CWF19L2 CWF19 like cell cycle control factor 2 [ Homo sapiens (human) ]

    Gene ID: 143884, updated on 5-May-2024


    Official Symbol
    CWF19L2provided by HGNC
    Official Full Name
    CWF19 like cell cycle control factor 2provided by HGNC
    Primary source
    See related
    Ensembl:ENSG00000152404 AllianceGenome:HGNC:26508
    Gene type
    protein coding
    RefSeq status
    Homo sapiens
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of post-mRNA release spliceosomal complex. [provided by Alliance of Genome Resources, Apr 2022]
    Ubiquitous expression in ovary (RPKM 6.7), endometrium (RPKM 5.9) and 25 other tissues See more
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    Genomic context

    See CWF19L2 in Genome Data Viewer
    Exon count:
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (107326360..107457825, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (107333512..107464989, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (107197086..107328551, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene argininosuccinate synthetase 1 pseudogene 13 Neighboring gene uncharacterized LOC105369477 Neighboring gene uncharacterized LOC124902745 Neighboring gene NANOG hESC enhancer GRCh37_chr11:107143023-107143770 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:107232171-107233370 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:107267561-107268760 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 pseudogene 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:107328330-107328835 Neighboring gene alkB homolog 8, tRNA methyltransferase Neighboring gene H3K27ac hESC enhancers GRCh37_chr11:107435812-107436330 and GRCh37_chr11:107436331-107436847 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5471 Neighboring gene SUCLG2 pseudogene 3

    Genomic regions, transcripts, and products


    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018


    Products Interactant Other Gene Complex Source Pubs Description

    General gene information


    Clone Names

    • FLJ32343

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    Component Evidence Code Pubs
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    part_of post-mRNA release spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info

    General protein information

    Preferred Names
    CWF19-like protein 2
    CWF19 like 2, cell cycle control

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_152434.3NP_689647.2  CWF19-like protein 2

      See identical proteins and their annotated locations for NP_689647.2

      Status: VALIDATED

      Source sequence(s)
      AK126881, BX648704
      Consensus CDS
      A4FU66, A4FU67, A4FU68, A8KAD6, Q2TBE0, Q6PHW1, Q96MI1
      ENSP00000282251.5, ENST00000282251.10
      Conserved Domains (2) summary
      CwfJ_C_2; Protein similar to CwfJ C-terminus 2
      HIT_like; HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis ...

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly


    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      107326360..107457825 complement
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047426419.1XP_047282375.1  CWF19-like protein 2 isoform X2

    2. XM_011542620.4XP_011540922.1  CWF19-like protein 2 isoform X1


    1. XR_007062452.1 RNA Sequence

    Alternate T2T-CHM13v2.0


    1. NC_060935.1 Alternate T2T-CHM13v2.0

      107333512..107464989 complement
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054367764.1XP_054223739.1  CWF19-like protein 2 isoform X2

    2. XM_054367763.1XP_054223738.1  CWF19-like protein 2 isoform X1


    1. XR_008488344.1 RNA Sequence