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    BANF2 BANF family member 2 [ Homo sapiens (human) ]

    Gene ID: 140836, updated on 8-Dec-2022

    Summary

    Official Symbol
    BANF2provided by HGNC
    Official Full Name
    BANF family member 2provided by HGNC
    Primary source
    HGNC:HGNC:16172
    See related
    Ensembl:ENSG00000125888 AllianceGenome:HGNC:16172
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    BAF2; BAFL; BAF-L; C20orf179
    Summary
    Enables identical protein binding activity. Predicted to be involved in chromosome condensation and chromosome segregation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis (RPKM 14.5) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See BANF2 in Genome Data Viewer
    Location:
    20p12.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    110 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (17693672..17735871)
    110 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (17744826..17787013)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (17674317..17716516)

    Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene ras homolog family member G pseudogene Neighboring gene destrin, actin depolymerizing factor Neighboring gene ribosome binding protein 1 Neighboring gene Sharpr-MPRA regulatory region 8855 Neighboring gene uncharacterized LOC105372547 Neighboring gene uncharacterized LOC107985440 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr20:17829988-17831187 Neighboring gene uncharacterized LOC105372548

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC62093, MGC72082

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus HDA PubMed 

    General protein information

    Preferred Names
    barrier-to-autointegration factor-like protein
    Names
    barrier to autointegration factor 2
    testis secretory sperm-binding protein Li 212a

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014977.4NP_001014977.2  barrier-to-autointegration factor-like protein isoform 1

      See identical proteins and their annotated locations for NP_001014977.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (1).
      Source sequence(s)
      AA394107, AW022487, BC054871
      Consensus CDS
      CCDS13129.1
      UniProtKB/Swiss-Prot
      Q7Z4M6, Q9H503
      UniProtKB/TrEMBL
      A0A140VK85
      Related
      ENSP00000367036.3, ENST00000377805.7
      Conserved Domains (1) summary
      cl03803
      Location:389
      BAF; Barrier to autointegration factor
    2. NM_001159495.2NP_001152967.1  barrier-to-autointegration factor-like protein isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate 5' exon and an upstream in-frame start codon, compared to variant 1. The resulting isoform (2) has a longer N-terminus compared to isoform 1.
      Source sequence(s)
      AA394107, AL132765, AW022487
      Consensus CDS
      CCDS54449.1
      UniProtKB/Swiss-Prot
      Q9H503
      Related
      ENSP00000439128.1, ENST00000545418.2
      Conserved Domains (1) summary
      cl03803
      Location:1096
      BAF; Barrier to autointegration factor
    3. NM_178477.5NP_848572.3  barrier-to-autointegration factor-like protein isoform 1

      See identical proteins and their annotated locations for NP_848572.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript but encodes the shorter isoform (1). Both variants 1 and 2 encode the same isoform (1).
      Source sequence(s)
      AA394107, AW022487, BC054871, BC062735
      Consensus CDS
      CCDS13129.1
      UniProtKB/Swiss-Prot
      Q7Z4M6, Q9H503
      UniProtKB/TrEMBL
      A0A140VK85
      Related
      ENSP00000246090.5, ENST00000246090.6
      Conserved Domains (1) summary
      cl03803
      Location:389
      BAF; Barrier to autointegration factor

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

      Range
      17693672..17735871
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005260668.4XP_005260725.1  barrier-to-autointegration factor-like protein isoform X2

      See identical proteins and their annotated locations for XP_005260725.1

      UniProtKB/Swiss-Prot
      Q7Z4M6, Q9H503
      UniProtKB/TrEMBL
      A0A140VK85
      Conserved Domains (1) summary
      cl03803
      Location:389
      BAF; Barrier to autointegration factor
    2. XM_011529170.2XP_011527472.1  barrier-to-autointegration factor-like protein isoform X1

      See identical proteins and their annotated locations for XP_011527472.1

      Conserved Domains (1) summary
      cl03803
      Location:894
      BAF; Barrier to autointegration factor
    3. XM_011529171.4XP_011527473.1  barrier-to-autointegration factor-like protein isoform X1

      See identical proteins and their annotated locations for XP_011527473.1

      Conserved Domains (1) summary
      cl03803
      Location:894
      BAF; Barrier to autointegration factor

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060944.1 Alternate T2T-CHM13v2.0

      Range
      17744826..17787013
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)