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    S100A16 S100 calcium binding protein A16 [ Homo sapiens (human) ]

    Gene ID: 140576, updated on 3-Jun-2019

    Summary

    Official Symbol
    S100A16provided by HGNC
    Official Full Name
    S100 calcium binding protein A16provided by HGNC
    Primary source
    HGNC:HGNC:20441
    See related
    Ensembl:ENSG00000188643 MIM:617437
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    AAG13; S100F; DT1P1A7
    Expression
    Biased expression in esophagus (RPKM 418.9), skin (RPKM 89.4) and 13 other tissues See more
    Orthologs

    Genomic context

    See S100A16 in Genome Data Viewer
    Location:
    1q21.3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 1 NC_000001.11 (153606883..153613168, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (153579362..153585514, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928034 Neighboring gene S100 calcium binding protein A3 Neighboring gene S100 calcium binding protein A2 Neighboring gene S100 calcium binding protein A14 Neighboring gene S100 calcium binding protein A13 Neighboring gene S100 calcium binding protein A1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC17528

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    RNA binding HDA PubMed 
    calcium ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    response to calcium ion IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular exosome HDA PubMed 
    extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
     

    General protein information

    Preferred Names
    protein S100-A16
    Names
    aging-associated gene 13 protein
    aging-associated protein 13
    protein S100-F

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001317007.1NP_001303936.1  protein S100-A16

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 all encode the same protein.
      Source sequence(s)
      AI673616, BC010541, BQ439720, HY178745
      Consensus CDS
      CCDS1045.1
      UniProtKB/Swiss-Prot
      Q96FQ6
      Related
      ENSP00000357694.1, ENST00000368705.2
      Conserved Domains (1) summary
      cd05022
      Location:699
      S-100A13; S-100A13: S-100A13 domain found in proteins similar to S100A13. S100A13 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, ...
    2. NM_001317008.1NP_001303937.1  protein S100-A16

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same protein.
      Source sequence(s)
      AI673616, BC010541, HY178745
      Consensus CDS
      CCDS1045.1
      UniProtKB/Swiss-Prot
      Q96FQ6
      Related
      ENSP00000357693.1, ENST00000368704.5
      Conserved Domains (1) summary
      cd05022
      Location:699
      S-100A13; S-100A13: S-100A13 domain found in proteins similar to S100A13. S100A13 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, ...
    3. NM_080388.3NP_525127.1  protein S100-A16

      See identical proteins and their annotated locations for NP_525127.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same protein.
      Source sequence(s)
      AI673616, BC010541, BM739127
      Consensus CDS
      CCDS1045.1
      UniProtKB/Swiss-Prot
      Q96FQ6
      Related
      ENSP00000357695.3, ENST00000368706.9
      Conserved Domains (1) summary
      cd05022
      Location:699
      S-100A13; S-100A13: S-100A13 domain found in proteins similar to S100A13. S100A13 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, ...

    RNA

    1. NR_133645.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses an alternate first exon and an alternate splice junction compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
      Source sequence(s)
      AI673616, AW954845, BC010541

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p12 Primary Assembly

      Range
      153606883..153613168 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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